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Items: 1 to 20 of 128

1.

The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome.

Newkirk DA, Chen YY, Chien R, Zeng W, Biesinger J, Flowers E, Kawauchi S, Santos R, Calof AL, Lander AD, Xie X, Yokomori K.

Clin Epigenetics. 2017 Aug 25;9:89. doi: 10.1186/s13148-017-0391-x. eCollection 2017.

2.

Expanding signaling-molecule wavefront model of cell polarization in the Drosophila wing primordium.

Wortman JC, Nahmad M, Zhang PC, Lander AD, Yu CC.

PLoS Comput Biol. 2017 Jul 3;13(7):e1005610. doi: 10.1371/journal.pcbi.1005610. eCollection 2017 Jul.

3.

Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro.

Hsia K, Yang MJ, Chen WM, Yao CL, Lin CH, Loong CC, Huang YL, Lin YT, Lander AD, Lee H, Lu JH.

Acta Biomater. 2017 Mar 15;51:341-350. doi: 10.1016/j.actbio.2017.01.050. Epub 2017 Jan 18.

PMID:
28110073
4.

Characterization of the upper pouch tracheo-oesophageal fistula in oesophageal atresia.

Summerour V, Stevens PS, Lander AD, Singh M, Soccorso G, Arul GS.

J Pediatr Surg. 2017 Feb;52(2):231-234. doi: 10.1016/j.jpedsurg.2016.11.009. Epub 2016 Nov 13.

PMID:
27939205
5.

Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.

Santos R, Kawauchi S, Jacobs RE, Lopez-Burks ME, Choi H, Wikenheiser J, Hallgrimsson B, Jamniczky HA, Fraser SE, Lander AD, Calof AL.

PLoS Biol. 2016 Sep 8;14(9):e2000197. doi: 10.1371/journal.pbio.2000197. eCollection 2016 Sep.

6.

Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis.

Wilkins JF, McHale PT, Gervin J, Lander AD.

PLoS Genet. 2016 Apr 28;12(4):e1006003. doi: 10.1371/journal.pgen.1006003. eCollection 2016 Apr.

7.

Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome.

Lopez-Burks ME, Santos R, Kawauchi S, Calof AL, Lander AD.

Am J Med Genet C Semin Med Genet. 2016 Jun;172(2):146-54. doi: 10.1002/ajmg.c.31491. Epub 2016 Apr 27.

8.

Using mouse and zebrafish models to understand the etiology of developmental defects in Cornelia de Lange Syndrome.

Kawauchi S, Santos R, Muto A, Lopez-Burks ME, Schilling TF, Lander AD, Calof AL.

Am J Med Genet C Semin Med Genet. 2016 Jun;172(2):138-45. doi: 10.1002/ajmg.c.31484. Epub 2016 Apr 27. Review.

9.

Feedback, Lineages and Self-Organizing Morphogenesis.

Kunche S, Yan H, Calof AL, Lowengrub JS, Lander AD.

PLoS Comput Biol. 2016 Mar 18;12(3):e1004814. doi: 10.1371/journal.pcbi.1004814. eCollection 2016 Mar.

10.

Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.

Kline AD, Calof AL, Lander AD, Gerton JL, Krantz ID, Dorsett D, Deardorff MA, Blagowidow N, Yokomori K, Shirahige K, Santos R, Woodman J, Megee PC, O'Connor JT, Egense A, Noon S, Belote M, Goodban MT, Hansen BD, Timmons JG, Musio A, Ishman SL, Bryan Y, Wu Y, Bettini LR, Mehta D, Zakari M, Mills JA, Srivastava S, Haaland RE.

Am J Med Genet A. 2015 Jun;167(6):1179-92. doi: 10.1002/ajmg.a.37056. Epub 2015 Apr 21.

PMID:
25899772
11.

Organ-level quorum sensing directs regeneration in hair stem cell populations.

Chen CC, Wang L, Plikus MV, Jiang TX, Murray PJ, Ramos R, Guerrero-Juarez CF, Hughes MW, Lee OK, Shi S, Widelitz RB, Lander AD, Chuong CM.

Cell. 2015 Apr 9;161(2):277-90. doi: 10.1016/j.cell.2015.02.016.

12.

Cell lineage branching as a strategy for proliferative control.

Buzi G, Lander AD, Khammash M.

BMC Biol. 2015 Feb 19;13:13. doi: 10.1186/s12915-015-0122-8.

13.

Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms.

Lo WC, Zhou S, Wan FY, Lander AD, Nie Q.

J R Soc Interface. 2015 Jan 6;12(102):20141041.

14.

Nipbl and mediator cooperatively regulate gene expression to control limb development.

Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF.

PLoS Genet. 2014 Sep 25;10(9):e1004671. doi: 10.1371/journal.pgen.1004671. eCollection 2014 Sep.

15.

Making sense in biology: an appreciation of Julian Lewis.

Lander AD.

BMC Biol. 2014 Aug 2;12:57. doi: 10.1186/s12915-014-0057-5. No abstract available.

16.

The protective role of symmetric stem cell division on the accumulation of heritable damage.

McHale PT, Lander AD.

PLoS Comput Biol. 2014 Aug 14;10(8):e1003802. doi: 10.1371/journal.pcbi.1003802. eCollection 2014 Aug.

17.

Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control.

Konstorum A, Sprowl SA, Waterman ML, Lander AD, Lowengrub JS.

J Coupled Syst Multiscale Dyn. 2013 Dec 1;1(4):459-467.

18.

A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain.

Srinivasan S, Hu JS, Currle DS, Fung ES, Hayes WB, Lander AD, Monuki ES.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003463. doi: 10.1371/journal.pcbi.1003463. eCollection 2014 Feb.

19.

Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I.

Visnes T, Giordano F, Kuznetsova A, Suja JA, Lander AD, Calof AL, Ström L.

Chromosoma. 2014 Jun;123(3):239-52. doi: 10.1007/s00412-013-0444-7. Epub 2013 Nov 28.

20.

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

Remeseiro S, Cuadrado A, Kawauchi S, Calof AL, Lander AD, Losada A.

Biochim Biophys Acta. 2013 Dec;1832(12):2097-102. doi: 10.1016/j.bbadis.2013.07.020. Epub 2013 Aug 3.

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