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Items: 1 to 20 of 97

  • The following term was not found in PubMed: L-7-Hydroxy-1.
1.

2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation.

Morishita K, Shoji Y, Fukui M, Ito Y, Kitao T, Ozawa SI, Hirono S, Shirahase H.

Chem Pharm Bull (Tokyo). 2018;66(12):1131-1152. doi: 10.1248/cpb.c18-00571.

2.

Quinapril.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

3.

Design and synthesis of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-1,2,3,4-tetrahydroisoquinoline-3-carboxamides as novel Hsp90 inhibitors.

Liang C, Hao H, Wu X, Li Z, Zhu J, Lu C, Shen Y.

Eur J Med Chem. 2016 Oct 4;121:272-282. doi: 10.1016/j.ejmech.2016.05.033. Epub 2016 May 20.

PMID:
27266997
4.

Novel 2,7-Substituted (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein-Tyrosine Phosphatase 1B Inhibition.

Otake K, Azukizawa S, Takeda S, Fukui M, Kawahara A, Kitao T, Shirahase H.

Chem Pharm Bull (Tokyo). 2015;63(12):998-1014. doi: 10.1248/cpb.c15-00508.

5.

Rational Design of a Dephosphorylation-Resistant Reporter Enables Single-Cell Measurement of Tyrosine Kinase Activity.

Turner AH, Lebhar MS, Proctor A, Wang Q, Lawrence DS, Allbritton NL.

ACS Chem Biol. 2016 Feb 19;11(2):355-62. doi: 10.1021/acschembio.5b00667. Epub 2015 Dec 4.

6.

Antiproliferative effect of isolated isoquinoline alkaloid from Mucuna pruriens seeds in hepatic carcinoma cells.

Kumar P, Rawat A, Keshari AK, Singh AK, Maity S, De A, Samanta A, Saha S.

Nat Prod Res. 2016;30(4):460-3. doi: 10.1080/14786419.2015.1020489. Epub 2015 Mar 16.

PMID:
25774560
7.

Diversity-oriented synthesis of medicinally important 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives and higher analogs.

Kotha S, Deodhar D, Khedkar P.

Org Biomol Chem. 2014 Dec 7;12(45):9054-91. doi: 10.1039/c4ob01446d. Review.

PMID:
25299735
8.

Hyalachelins A-C, unusual siderophores isolated from the terrestrial myxobacterium Hyalangium minutum.

Nadmid S, Plaza A, Lauro G, Garcia R, Bifulco G, Müller R.

Org Lett. 2014 Aug 15;16(16):4130-3. doi: 10.1021/ol501826a. Epub 2014 Jul 24.

PMID:
25058569
10.

N-terminal guanidinylation of TIPP (Tyr-Tic-Phe-Phe) peptides results in major changes of the opioid activity profile.

Weltrowska G, Nguyen TM, Chung NN, Wilkes BC, Schiller PW.

Bioorg Med Chem Lett. 2013 Sep 15;23(18):5082-5. doi: 10.1016/j.bmcl.2013.07.036. Epub 2013 Jul 23.

11.

Practical synthesis of (20S)-10-(3-aminopropyloxy)-7-ethylcamptothecin, a water-soluble analogue of camptothecin.

Watanabe T, Tsuboi Y, Nomura S.

Chem Asian J. 2013 Mar;8(3):630-8. doi: 10.1002/asia.201200904. Epub 2012 Dec 23.

PMID:
23281180
12.

Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

Al-Horani RA, Mehta AY, Desai UR.

Eur J Med Chem. 2012 Aug;54:771-83. doi: 10.1016/j.ejmech.2012.06.032. Epub 2012 Jun 23.

13.
14.

pH-Dependent nanostructure based on isoquinoline-cyclodextrin conjugate for thrombosis therapy.

Li L, Zhao M, Li W, Wang Y, Liu C, Zhang Z, Su S, Peng S.

Nanomedicine. 2012 Oct;8(7):1216-22. doi: 10.1016/j.nano.2011.12.008. Epub 2012 Jan 14.

PMID:
22248818
15.

Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition.

Otake K, Azukizawa S, Fukui M, Kunishiro K, Kamemoto H, Kanda M, Miike T, Kasai M, Shirahase H.

Bioorg Med Chem. 2012 Jan 15;20(2):1060-75. doi: 10.1016/j.bmc.2011.11.035. Epub 2011 Dec 1.

PMID:
22197396
16.

Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two components.

Ding J, Lemieux C, Chung NN, Schiller PW.

Chem Biol Drug Des. 2012 Feb;79(2):186-93. doi: 10.1111/j.1747-0285.2011.01268.x. Epub 2012 Jan 4.

17.

A novel series of (S)-2,7-substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: peroxisome proliferator-activated receptor α/γ dual agonists with protein-tyrosine phosphatase 1B inhibitory activity.

Otake K, Azukizawa S, Fukui M, Shibabayashi M, Kamemoto H, Miike T, Kunishiro K, Kasai M, Shirahase H.

Chem Pharm Bull (Tokyo). 2011;59(10):1233-42.

18.

Variation of the intercalating proline in artificial peptides mimicking the DNA binding and bending IHF protein.

Scholz S, Liebler EK, Eickmann B, Fritz HJ, Diederichsen U.

Amino Acids. 2012 Jul;43(1):289-98. doi: 10.1007/s00726-011-1073-1. Epub 2011 Sep 16.

19.

Design, synthesis and biological evaluation of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as aminopeptidase N/CD13 inhibitors.

Zhang X, Zhang J, Zhang L, Feng J, Xu Y, Yuan Y, Fang H, Xu W.

Bioorg Med Chem. 2011 Oct 15;19(20):6015-25. doi: 10.1016/j.bmc.2011.08.041. Epub 2011 Aug 24.

PMID:
21911297
20.

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