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Items: 1 to 20 of 129

1.

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.

Lindqvist CM, Lundmark A, Nordlund J, Freyhult E, Ekman D, Carlsson Almlöf J, Raine A, Övernäs E, Abrahamsson J, Frost BM, Grandér D, Heyman M, Palle J, Forestier E, Lönnerholm G, Berglund EC, Syvänen AC.

Oncotarget. 2016 Sep 27;7(39):64071-64088. doi: 10.18632/oncotarget.11773.

2.

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.

Wahlberg P, Lundmark A, Nordlund J, Busche S, Raine A, Tandre K, Rönnblom L, Sinnett D, Forestier E, Pastinen T, Lönnerholm G, Syvänen AC.

Epigenomics. 2016 Oct;8(10):1367-1387. Epub 2016 Aug 23.

3.

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array.

Marzouka NA, Nordlund J, Bäcklin CL, Lönnerholm G, Syvänen AC, Carlsson Almlöf J.

Bioinformatics. 2016 Apr 1;32(7):1080-2. doi: 10.1093/bioinformatics/btv652. Epub 2015 Nov 9.

4.

PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia.

Marincevic-Zuniga Y, Zachariadis V, Cavelier L, Castor A, Barbany G, Forestier E, Fogelstrand L, Heyman M, Abrahamsson J, Lönnerholm G, Nordgren A, Syvänen AC, Nordlund J.

Haematologica. 2016 Jan;101(1):e20-3. doi: 10.3324/haematol.2015.132332. Epub 2015 Oct 22. No abstract available.

5.

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.

Nordlund J, Bäcklin CL, Zachariadis V, Cavelier L, Dahlberg J, Öfverholm I, Barbany G, Nordgren A, Övernäs E, Abrahamsson J, Flaegstad T, Heyman MM, Jónsson ÓG, Kanerva J, Larsson R, Palle J, Schmiegelow K, Gustafsson MG, Lönnerholm G, Forestier E, Syvänen AC.

Clin Epigenetics. 2015 Feb 17;7:11. doi: 10.1186/s13148-014-0039-z. eCollection 2015.

6.

The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.

Lindqvist CM, Nordlund J, Ekman D, Johansson A, Moghadam BT, Raine A, Övernäs E, Dahlberg J, Wahlberg P, Henriksson N, Abrahamsson J, Frost BM, Grandér D, Heyman M, Larsson R, Palle J, Söderhäll S, Forestier E, Lönnerholm G, Syvänen AC, Berglund EC.

Hum Mutat. 2015 Jan;36(1):118-28. doi: 10.1002/humu.22719.

7.

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment.

Berglund EC, Lindqvist CM, Hayat S, Övernäs E, Henriksson N, Nordlund J, Wahlberg P, Forestier E, Lönnerholm G, Syvänen AC.

BMC Genomics. 2013 Dec 5;14:856. doi: 10.1186/1471-2164-14-856.

8.

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.

Nordlund J, Bäcklin CL, Wahlberg P, Busche S, Berglund EC, Eloranta ML, Flaegstad T, Forestier E, Frost BM, Harila-Saari A, Heyman M, Jónsson OG, Larsson R, Palle J, Rönnblom L, Schmiegelow K, Sinnett D, Söderhäll S, Pastinen T, Gustafsson MG, Lönnerholm G, Syvänen AC.

Genome Biol. 2013 Sep 24;14(9):r105. doi: 10.1186/gb-2013-14-9-r105.

9.

DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission.

Nordlund J, Milani L, Lundmark A, Lönnerholm G, Syvänen AC.

PLoS One. 2012;7(4):e34513. doi: 10.1371/journal.pone.0034513. Epub 2012 Apr 6.

10.

Digital gene expression profiling of primary acute lymphoblastic leukemia cells.

Nordlund J, Kiialainen A, Karlberg O, Berglund EC, Göransson-Kultima H, Sønderkær M, Nielsen KL, Gustafsson MG, Behrendtz M, Forestier E, Perkkiö M, Söderhäll S, Lönnerholm G, Syvänen AC.

Leukemia. 2012 Jun;26(6):1218-27. doi: 10.1038/leu.2011.358. Epub 2011 Dec 16.

11.

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia.

Staffas A, Kanduri M, Hovland R, Rosenquist R, Ommen HB, Abrahamsson J, Forestier E, Jahnukainen K, Jónsson ÓG, Zeller B, Palle J, Lönnerholm G, Hasle H, Palmqvist L, Ehrencrona H; Nordic Society of Pediatric Hematology and Oncology (NOPHO).

Blood. 2011 Nov 24;118(22):5905-13. doi: 10.1182/blood-2011-05-353185. Epub 2011 Oct 3.

12.

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

Thörn I, Forestier E, Botling J, Thuresson B, Wasslavik C, Björklund E, Li A, Lindström-Eriksson E, Malec M, Grönlund E, Torikka K, Heldrup J, Abrahamsson J, Behrendtz M, Söderhäll S, Jacobsson S, Olofsson T, Porwit A, Lönnerholm G, Rosenquist R, Sundström C.

Br J Haematol. 2011 Mar;152(6):743-53. doi: 10.1111/j.1365-2141.2010.08456.x. Epub 2011 Jan 20.

PMID:
21250970
13.

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial.

Zachariadis V, Gauffin F, Kuchinskaya E, Heyman M, Schoumans J, Blennow E, Gustafsson B, Barbany G, Golovleva I, Ehrencrona H, Cavelier L, Palmqvist L, Lönnerholm G, Nordenskjöld M, Johansson B, Forestier E, Nordgren A; Nordic Society of Pediatric Hematology, Oncology (NOPHO); Swedish Cytogenetic Leukemia Study Group (SCLSG).

Leukemia. 2011 Apr;25(4):622-8. doi: 10.1038/leu.2010.318. Epub 2011 Jan 18.

PMID:
21242996
14.

In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia.

Lönnerholm G, Thörn I, Sundström C, Frost BM, Flaegstad T, Heyman M, Jonsson OG, Harila-Saari A, Madsen HO, Porwit A, Schmiegelow K, Söderhäll S, Wesenberg F, Vettenranta K, Larsson R, Forestier E.

Leuk Res. 2011 Apr;35(4):472-8. doi: 10.1016/j.leukres.2010.09.001. Epub 2010 Oct 18.

PMID:
20961616
15.

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.

Milani L, Lundmark A, Kiialainen A, Nordlund J, Flaegstad T, Forestier E, Heyman M, Jonmundsson G, Kanerva J, Schmiegelow K, Söderhäll S, Gustafsson MG, Lönnerholm G, Syvänen AC.

Blood. 2010 Feb 11;115(6):1214-25. doi: 10.1182/blood-2009-04-214668. Epub 2009 Nov 25.

16.

Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia.

Palle J, Frost BM, Petersson C, Hasle H, Hellebostad M, Kanerva J, Schmiegelow K, Lönnerholm G; Nordic Society for Paediatric Haematology and Oncology.

Anticancer Drugs. 2009 Jan;20(1):7-14. doi: 10.1097/CAD.0b013e32831bc086. Erratum in: Anticancer Drugs. 2010 Jan;21(1):130. Josefine, Palle [corrected to Palle, Josefine]; Britt-Marie, Frost [corrected to Frost, Britt-Marie]; Curt, Petersson [corrected to Petersson, Curt]; Henrik, Hasle [corrected to Hasle, Henrik]; Marit, Hellebostad [corrected to Hellebostad, Marit]; Jukka, Kanerva [corrected to Kanerva, Jukka]; Kjeld, Schmiegelow [corrected to Schmiegelow, Kjeld]; Gudmar, Lönnerholm [corrected to Lönnerholm, Gudmar].

PMID:
19342996
17.

Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia.

Thörn I, Botling J, Hermansson M, Lönnerholm G, Sundström C, Rosenquist R, Barbany G.

Leuk Res. 2009 Aug;33(8):1047-54. doi: 10.1016/j.leukres.2008.11.031. Epub 2009 Jan 20.

PMID:
19157547
18.

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia.

Lönnerholm G, Valsecchi MG, De Lorenzo P, Schrappe M, Hovi L, Campbell M, Mann G, Janka-Schaub G, Li CK, Stary J, Hann I, Pieters R; Interfant-99 study group.

Pediatr Blood Cancer. 2009 May;52(5):596-601. doi: 10.1002/pbc.21925.

PMID:
19132729
19.

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation.

Milani L, Lundmark A, Nordlund J, Kiialainen A, Flaegstad T, Jonmundsson G, Kanerva J, Schmiegelow K, Gunderson KL, Lönnerholm G, Syvänen AC.

Genome Res. 2009 Jan;19(1):1-11. doi: 10.1101/gr.083931.108. Epub 2008 Nov 7.

20.

In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia.

Lönnerholm G, Thörn I, Sundström C, Frost BM, Abrahamsson J, Behrendtz M, Heldrup J, Jacobsson S, Li A, Olofsson T, Porwit A, Söderhäll S, Larsson R, Forestier E.

Leuk Res. 2009 Jan;33(1):46-53. doi: 10.1016/j.leukres.2008.06.012. Epub 2008 Jul 17.

PMID:
18639340

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