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The bromodomain protein BRD4 regulates splicing during heat shock.

Hussong M, Kaehler C, Kerick M, Grimm C, Franz A, Timmermann B, Welzel F, Isensee J, Hucho T, Krobitsch S, Schweiger MR.

Nucleic Acids Res. 2016 Aug 17. pii: gkw729.


PRMT1-mediated arginine methylation controls ATXN2L localization.

Kaehler C, Guenther A, Uhlich A, Krobitsch S.

Exp Cell Res. 2015 May 15;334(1):114-25. doi: 10.1016/j.yexcr.2015.02.022.


5-Fluorouracil affects assembly of stress granules based on RNA incorporation.

Kaehler C, Isensee J, Hucho T, Lehrach H, Krobitsch S.

Nucleic Acids Res. 2014 Jun;42(10):6436-47. doi: 10.1093/nar/gku264.


High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications.

Röhr C, Kerick M, Fischer A, Kühn A, Kashofer K, Timmermann B, Daskalaki A, Meinel T, Drichel D, Börno ST, Nowka A, Krobitsch S, McHardy AC, Kratsch C, Becker T, Wunderlich A, Barmeyer C, Viertler C, Zatloukal K, Wierling C, Lehrach H, Schweiger MR.

PLoS One. 2013;8(7):e67461. doi: 10.1371/journal.pone.0067461.


Fkh1 and Fkh2 associate with Sir2 to control CLB2 transcription under normal and oxidative stress conditions.

Linke C, Klipp E, Lehrach H, Barberis M, Krobitsch S.

Front Physiol. 2013 Jul 12;4:173. doi: 10.3389/fphys.2013.00173.


Ataxin-2-like is a regulator of stress granules and processing bodies.

Kaehler C, Isensee J, Nonhoff U, Terrey M, Hucho T, Lehrach H, Krobitsch S.

PLoS One. 2012;7(11):e50134. doi: 10.1371/journal.pone.0050134.


FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression.

Welzel F, Kaehler C, Isau M, Hallen L, Lehrach H, Krobitsch S.

PLoS One. 2012;7(5):e37985. doi: 10.1371/journal.pone.0037985.


Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information.

Meinel T, Schweiger MR, Ludewig AH, Chenna R, Krobitsch S, Herwig R.

BMC Genomics. 2011 Oct 4;12:483. doi: 10.1186/1471-2164-12-483.


Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins.

Barberis M, Linke C, Adrover MÀ, González-Novo A, Lehrach H, Krobitsch S, Posas F, Klipp E.

Biotechnol Adv. 2012 Jan-Feb;30(1):108-30. doi: 10.1016/j.biotechadv.2011.09.004.


Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity.

Kerick M, Isau M, Timmermann B, Sültmann H, Herwig R, Krobitsch S, Schaefer G, Verdorfer I, Bartsch G, Klocker H, Lehrach H, Schweiger MR.

BMC Med Genomics. 2011 Sep 29;4:68. doi: 10.1186/1755-8794-4-68.


Effects of EpCAM overexpression on human breast cancer cell lines.

Gostner JM, Fong D, Wrulich OA, Lehne F, Zitt M, Hermann M, Krobitsch S, Martowicz A, Gastl G, Spizzo G.

BMC Cancer. 2011 Jan 31;11:45. doi: 10.1186/1471-2407-11-45.


The effect of micrococcal nuclease digestion on nucleosome positioning data.

Chung HR, Dunkel I, Heise F, Linke C, Krobitsch S, Ehrenhofer-Murray AE, Sperling SR, Vingron M.

PLoS One. 2010 Dec 29;5(12):e15754. doi: 10.1371/journal.pone.0015754.


Huntington's disease: From molecular basis to therapeutic advances.

Krobitsch S, Kazantsev AG.

Int J Biochem Cell Biol. 2011 Jan;43(1):20-4. doi: 10.1016/j.biocel.2010.10.014. Review.


The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.

Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S.

Hum Mol Genet. 2011 Jan 1;20(1):104-14. doi: 10.1093/hmg/ddq436.


Minimum information about a protein affinity reagent (MIAPAR).

Bourbeillon J, Orchard S, Benhar I, Borrebaeck C, de Daruvar A, Dübel S, Frank R, Gibson F, Gloriam D, Haslam N, Hiltker T, Humphrey-Smith I, Hust M, Juncker D, Koegl M, Konthur Z, Korn B, Krobitsch S, Muyldermans S, Nygren PA, Palcy S, Polic B, Rodriguez H, Sawyer A, Schlapshy M, Snyder M, Stoevesandt O, Taussig MJ, Templin M, Uhlen M, van der Maarel S, Wingren C, Hermjakob H, Sherman D.

Nat Biotechnol. 2010 Jul;28(7):650-3. doi: 10.1038/nbt0710-650. No abstract available.


Transcriptome analysis by strand-specific sequencing of complementary DNA.

Parkhomchuk D, Borodina T, Amstislavskiy V, Banaru M, Hallen L, Krobitsch S, Lehrach H, Soldatov A.

Nucleic Acids Res. 2009 Oct;37(18):e123. doi: 10.1093/nar/gkp596.


A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.

Ralser M, Wamelink MM, Struys EA, Joppich C, Krobitsch S, Jakobs C, Lehrach H.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17807-11. doi: 10.1073/pnas.0803090105.


Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans.

Ralser M, Nebel A, Kleindorp R, Krobitsch S, Lehrach H, Schreiber S, Reinhardt R, Timmermann B.

BMC Genet. 2008 May 29;9:38. doi: 10.1186/1471-2156-9-38.


Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

Ralser M, Wamelink MM, Kowald A, Gerisch B, Heeren G, Struys EA, Klipp E, Jakobs C, Breitenbach M, Lehrach H, Krobitsch S.

J Biol. 2007 Dec 21;6(4):10.


Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.

Nonhoff U, Ralser M, Welzel F, Piccini I, Balzereit D, Yaspo ML, Lehrach H, Krobitsch S.

Mol Biol Cell. 2007 Apr;18(4):1385-96.

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