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Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass.

Schulze CJ, Castro MM, Kandasamy AD, Cena J, Bryden C, Wang SH, Koshal A, Tsuyuki RT, Finegan BA, Schulz R.

Crit Care Med. 2013 Nov;41(11):2512-20. doi: 10.1097/CCM.0b013e318292373c.


Strategies for multivessel revascularization in patients with diabetes.

Farkouh ME, Domanski M, Sleeper LA, Siami FS, Dangas G, Mack M, Yang M, Cohen DJ, Rosenberg Y, Solomon SD, Desai AS, Gersh BJ, Magnuson EA, Lansky A, Boineau R, Weinberger J, Ramanathan K, Sousa JE, Rankin J, Bhargava B, Buse J, Hueb W, Smith CR, Muratov V, Bansilal S, King S 3rd, Bertrand M, Fuster V; FREEDOM Trial Investigators.

N Engl J Med. 2012 Dec 20;367(25):2375-84. doi: 10.1056/NEJMoa1211585. Epub 2012 Nov 4.


Outcomes of after-hours versus regular working hours primary percutaneous coronary intervention for acute myocardial infarction.

Graham MM, Ghali WA, Southern DA, Traboulsi M, Knudtson ML; APPROACH Investigators.

BMJ Qual Saf. 2011 Jan;20(1):60-7. doi: 10.1136/bmjqs.2010.041137.


Selective antegrade cerebral perfusion during aortic arch surgery confers survival and neuroprotective advantages.

Shihata M, Mittal R, Senthilselvan A, Ross D, Koshal A, Mullen J, MacArthur R.

J Thorac Cardiovasc Surg. 2011 Apr;141(4):948-52. doi: 10.1016/j.jtcvs.2010.06.047. Epub 2010 Aug 2.


Effect of beta-blocker use on outcomes after discharge in patients who underwent cardiac surgery.

Chan AY, McAlister FA, Norris CM, Johnstone D, Bakal JA, Ross DB; Alberta Provincial Program for Outcome Assessment in Coronary Heart Disease (APPROACH) Investigators.

J Thorac Cardiovasc Surg. 2010 Jul;140(1):182-7, 187.e1. doi: 10.1016/j.jtcvs.2010.03.015. Epub 2010 Apr 28.


Phosphorylcholine-coated circuits improve preservation of platelet count and reduce expression of proinflammatory cytokines in CABG: a prospective randomized trial.

Schulze CJ, Han L, Ghorpade N, Etches WS, Stang L, Koshal A, Wang SH.

J Card Surg. 2009 Jul-Aug;24(4):363-8. doi: 10.1111/j.1540-8191.2009.00895.x.


Long-term outcomes of patients receiving drug-eluting stents.

Philpott AC, Southern DA, Clement FM, Galbraith PD, Traboulsi M, Knudtson ML, Ghali WA; APPROACH Investigators.

CMAJ. 2009 Jan 20;180(2):167-74. doi: 10.1503/cmaj.080050. Epub 2008 Dec 18.


A comparison of aprotinin and lysine analogues in high-risk cardiac surgery.

Fergusson DA, Hébert PC, Mazer CD, Fremes S, MacAdams C, Murkin JM, Teoh K, Duke PC, Arellano R, Blajchman MA, Bussières JS, Côté D, Karski J, Martineau R, Robblee JA, Rodger M, Wells G, Clinch J, Pretorius R; BART Investigators.

N Engl J Med. 2008 May 29;358(22):2319-31. doi: 10.1056/NEJMoa0802395. Epub 2008 May 14. Erratum in: N Engl J Med. 2010 Sep 23;363(13):1290.


Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.

Manji RA, Zhu LF, Nijjar NK, Rayner DC, Korbutt GS, Churchill TA, Rajotte RV, Koshal A, Ross DB.

Circulation. 2006 Jul 25;114(4):318-27. Epub 2006 Jul 10.


Pretransplant diabetes, not donor age, predicts long-term outcomes in cardiac transplantation.

Meyer SR, Modry DL, Norris CM, Pearson GJ, Bentley MJ, Koshal A, Mullen JC, Rebeyka IM, Ross DB, Wang S.

J Card Surg. 2006 Mar-Apr;21(2):117-24.


Is mitral valve surgery safe in octogenarians?

Nagendran J, Norris C, Maitland A, Koshal A, Ross DB.

Eur J Cardiothorac Surg. 2005 Jul;28(1):83-7. Epub 2005 Apr 20.


Saphenous vein harvest with SaphLITE system versus conventional technique: a prospective, randomized study.

Wang S, Tang H, Wilkinson V, Lukat T, Gelfand ET, Koshal A, Modry DL, Mullen JC, Hao C, Finegan BA.

Ann Thorac Surg. 2005 Jun;79(6):2018-23.


Combined administration of nitric oxide gas and iloprost during cardiopulmonary bypass reduces platelet dysfunction: a pilot clinical study.

Chung A, Wildhirt SM, Wang S, Koshal A, Radomski MW.

J Thorac Cardiovasc Surg. 2005 Apr;129(4):782-90.


Declining need for permanent pacemaker insertion with the bicaval technique of orthotopic heart transplantation.

Meyer SR, Modry DL, Bainey K, Koshal A, Mullen JC, Rebeyka IM, Ross DB, Bowker S, Wang S.

Can J Cardiol. 2005 Feb;21(2):159-63.


A comparative analysis of outcome after heart transplantation in patients aged 60 years and older: the University of Alberta experience.

Nagendran J, Wildhirt SM, Modry D, Mullen J, Koshal A, Wang SH.

J Card Surg. 2004 Nov-Dec;19(6):559-62.


Long-term outcome of isolated coronary artery bypass surgery in patients with severe left ventricular dysfunction.

Appoo J, Norris C, Merali S, Graham MM, Koshal A, Knudtson ML, Ghali WA.

Circulation. 2004 Sep 14;110(11 Suppl 1):II13-7.


Increased apoptosis in porcine cardiac xenografts perfused with human ABO plasma containing the anti-B antibody.

Manji JS, Rajotte RV, Koshal A, Manji RA.

Xenotransplantation. 2004 Jul;11(4):378-9. No abstract available.


Human anti-A and anti-B antibodies interact with alphaGal antibody affecting xenograft survival.

Manji JS, Rajotte RV, Koshal A, Manji RA.

Xenotransplantation. 2004 Jul;11(4):376-7. No abstract available.


Under-utilization of mechanical circulatory support in Canada: why and what can be done?

Mussivand T, Carrier M, Chiu RC, Davies RA, Delgado DH, Deng MC, Haddad H, Hendry PJ, Keon WJ, Koshal A, Masters RG, Mesana T, Rao V.

Artif Organs. 2004 Mar;28(3):278-86.


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