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Items: 1 to 20 of 62

1.

Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism.

Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Korth MJ, Zink EM, Kim YM, Schepmoes AA, Nicora CD, Purvine SO, Weitz KK, Peng X, Green RR, Tilton SC, Webb-Robertson BJ, Waters KM, Metz TO, Smith RD, Kawaoka Y, Suresh M, Josset L, Katze MG.

Cell Host Microbe. 2016 Feb 10;19(2):254-66. doi: 10.1016/j.chom.2016.01.002.

2.

Delayed inflammatory and cell death responses are associated with reduced pathogenicity in Lujo virus-infected cynomolgus macaques.

Rasmussen AL, Tchitchek N, Safronetz D, Carter VS, Williams CM, Haddock E, Korth MJ, Feldmann H, Katze MG.

J Virol. 2015 Mar;89(5):2543-52. doi: 10.1128/JVI.02246-14. Epub 2014 Dec 17.

3.

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG.

Science. 2014 Nov 21;346(6212):987-91. doi: 10.1126/science.1259595. Epub 2014 Oct 30.

4.

Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy.

Peng X, Sova P, Green RR, Thomas MJ, Korth MJ, Proll S, Xu J, Cheng Y, Yi K, Chen L, Peng Z, Wang J, Palermo RE, Katze MG.

J Virol. 2014 Aug;88(16):8768-82. doi: 10.1128/JVI.00768-14. Epub 2014 May 21.

5.

Old world monkeys and new age science: the evolution of nonhuman primate systems virology.

Palermo RE, Tisoncik-Go J, Korth MJ, Katze MG.

ILAR J. 2013;54(2):166-80. doi: 10.1093/ilar/ilt039. Review.

6.

Drug repurposing: a better approach for infectious disease drug discovery?

Law GL, Tisoncik-Go J, Korth MJ, Katze MG.

Curr Opin Immunol. 2013 Oct;25(5):588-92. doi: 10.1016/j.coi.2013.08.004. Epub 2013 Sep 5. Review.

7.

Systems virology: host-directed approaches to viral pathogenesis and drug targeting.

Law GL, Korth MJ, Benecke AG, Katze MG.

Nat Rev Microbiol. 2013 Jul;11(7):455-66. doi: 10.1038/nrmicro3036. Epub 2013 Jun 3. Review.

8.

Systems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic viruses.

Korth MJ, Tchitchek N, Benecke AG, Katze MG.

Semin Immunol. 2013 Oct 31;25(3):228-39. doi: 10.1016/j.smim.2012.11.001. Epub 2012 Dec 5. Review.

9.

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.

Rasmussen AL, Wang IM, Shuhart MC, Proll SC, He Y, Cristescu R, Roberts C, Carter VS, Williams CM, Diamond DL, Bryan JT, Ulrich R, Korth MJ, Thomassen LV, Katze MG.

Virology. 2012 Aug 15;430(1):43-52. doi: 10.1016/j.virol.2012.04.011. Epub 2012 May 16.

10.

Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.

Navare AT, Sova P, Purdy DE, Weiss JM, Wolf-Yadlin A, Korth MJ, Chang ST, Proll SC, Jahan TA, Krasnoselsky AL, Palermo RE, Katze MG.

Virology. 2012 Jul 20;429(1):37-46. doi: 10.1016/j.virol.2012.03.026. Epub 2012 Apr 26.

11.

Into the eye of the cytokine storm.

Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG.

Microbiol Mol Biol Rev. 2012 Mar;76(1):16-32. doi: 10.1128/MMBR.05015-11. Review.

12.

Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients.

Rasmussen AL, Tchitchek N, Susnow NJ, Krasnoselsky AL, Diamond DL, Yeh MM, Proll SC, Korth MJ, Walters KA, Lederer S, Larson AM, Carithers RL, Benecke A, Katze MG.

Hepatology. 2012 Jul;56(1):17-27. doi: 10.1002/hep.25612. Epub 2012 Jun 5.

13.

Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Carter VS, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2012 Mar;86(5):2437-46. doi: 10.1128/JVI.06156-11. Epub 2011 Dec 21.

14.

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection.

Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, Katze MG.

MBio. 2011 Nov 15;2(6). pii: e00198-11. doi: 10.1128/mBio.00198-11. Print 2011.

15.

Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis.

Rasmussen AL, Diamond DL, McDermott JE, Gao X, Metz TO, Matzke MM, Carter VS, Belisle SE, Korth MJ, Waters KM, Smith RD, Katze MG.

J Virol. 2011 Nov;85(22):11646-54. doi: 10.1128/JVI.05605-11. Epub 2011 Sep 14.

16.

Functional genomics reveals the induction of inflammatory response and metalloproteinase gene expression during lethal Ebola virus infection.

Cilloniz C, Ebihara H, Ni C, Neumann G, Korth MJ, Kelly SM, Kawaoka Y, Feldmann H, Katze MG.

J Virol. 2011 Sep;85(17):9060-8. doi: 10.1128/JVI.00659-11. Epub 2011 Jul 6.

17.

The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.

Tisoncik JR, Billharz R, Burmakina S, Belisle SE, Proll SC, Korth MJ, García-Sastre A, Katze MG.

J Gen Virol. 2011 Sep;92(Pt 9):2093-104. doi: 10.1099/vir.0.032060-0. Epub 2011 May 18. Erratum in: J Gen Virol. 2011 Oct;92(Pt 10):2466. Garcíia-Sastre, Adolfo [corrected to García-Sastre, Adolfo].

18.

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

Aderem A, Adkins JN, Ansong C, Galagan J, Kaiser S, Korth MJ, Law GL, McDermott JG, Proll SC, Rosenberger C, Schoolnik G, Katze MG.

MBio. 2011 Mar 1;2(1):e00325-10. doi: 10.1128/mBio.00325-10.

19.

Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.

Safronetz D, Rockx B, Feldmann F, Belisle SE, Palermo RE, Brining D, Gardner D, Proll SC, Marzi A, Tsuda Y, Lacasse RA, Kercher L, York A, Korth MJ, Long D, Rosenke R, Shupert WL, Aranda CA, Mattoon JS, Kobasa D, Kobinger G, Li Y, Taubenberger JK, Richt JA, Parnell M, Ebihara H, Kawaoka Y, Katze MG, Feldmann H.

J Virol. 2011 Feb;85(3):1214-23. doi: 10.1128/JVI.01848-10. Epub 2010 Nov 17.

20.

Genomic analysis reveals pre- and postchallenge differences in a rhesus macaque AIDS vaccine trial: insights into mechanisms of vaccine efficacy.

Palermo RE, Patterson LJ, Aicher LD, Korth MJ, Robert-Guroff M, Katze MG.

J Virol. 2011 Jan;85(2):1099-116. doi: 10.1128/JVI.01522-10. Epub 2010 Nov 10.

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