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Items: 1 to 20 of 169

1.

Thermophilic phosphoribosyltransferases Thermus thermophilus HB27 in nucleotide synthesis.

Fateev IV, Sinitsina EV, Bikanasova AU, Kostromina MA, Tuzova ES, Esipova LV, Muravyova TI, Kayushin AL, Konstantinova ID, Esipov RS.

Beilstein J Org Chem. 2018 Dec 21;14:3098-3105. doi: 10.3762/bjoc.14.289. eCollection 2018.

2.

Enzymatic synthesis of novel purine nucleosides bearing a chiral benzoxazine fragment.

Eletskaya BZ, Gruzdev DA, Krasnov VP, Levit GL, Kostromina MA, Paramonov AS, Kayushin AL, Muzyka IS, Muravyova TI, Esipov RS, Andronova VL, Galegov GA, Charushin VN, Miroshnikov AI, Konstantinova ID.

Chem Biol Drug Des. 2019 Apr;93(4):605-616. doi: 10.1111/cbdd.13458. Epub 2019 Jan 20.

PMID:
30561886
3.

The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.

Wettstein G, Luccarini JM, Poekes L, Faye P, Kupkowski F, Adarbes V, Defrêne E, Estivalet C, Gawronski X, Jantzen I, Philippot A, Tessier J, Tuyaa-Boustugue P, Oakley F, Mann DA, Leclercq I, Francque S, Konstantinova I, Broqua P, Junien JL.

Hepatol Commun. 2017 Jun 19;1(6):524-537. doi: 10.1002/hep4.1057. eCollection 2017 Aug.

4.

Isosteric ribavirin analogues: Synthesis and antiviral activities.

Zhurilo NI, Chudinov MV, Matveev AV, Smirnova OS, Konstantinova ID, Miroshnikov AI, Prutkov AN, Grebenkina LE, Pulkova NV, Shvets VI.

Bioorg Med Chem Lett. 2018 Jan 1;28(1):11-14. doi: 10.1016/j.bmcl.2017.11.029. Epub 2017 Nov 15.

PMID:
29173944
5.

Pan-PPAR agonist IVA337 is effective in experimental lung fibrosis and pulmonary hypertension.

Avouac J, Konstantinova I, Guignabert C, Pezet S, Sadoine J, Guilbert T, Cauvet A, Tu L, Luccarini JM, Junien JL, Broqua P, Allanore Y.

Ann Rheum Dis. 2017 Nov;76(11):1931-1940. doi: 10.1136/annrheumdis-2016-210821. Epub 2017 Aug 11.

PMID:
28801346
6.

New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1.

Kharitonova MI, Denisova AO, Andronova VL, Kayushin AL, Konstantinova ID, Kotovskaya SK, Galegov GA, Charushin VN, Miroshnikov AI.

Bioorg Med Chem Lett. 2017 Jun 1;27(11):2484-2487. doi: 10.1016/j.bmcl.2017.03.100. Epub 2017 Apr 1.

PMID:
28408228
7.

A Cascade of Thermophilic Enzymes As an Approach to the Synthesis of Modified Nucleotides.

Esipov RS, Abramchik YA, Fateev IV, Konstantinova ID, Kostromina MA, Muravyova TI, Artemova KG, Miroshnikov AI.

Acta Naturae. 2016 Oct-Dec;8(4):82-90.

8.

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension.

Shaw DE, Baig F, Bruce I, Chamoin S, Collingwood SP, Cross S, Dayal S, Drückes P, Furet P, Furminger V, Haggart D, Hussey M, Konstantinova I, Loren JC, Molteni V, Roberts S, Reilly J, Saunders AM, Stringer R, Sviridenko L, Thomas M, Thomson CG, Tomlins C, Wen B, Yeh V, Pearce AC.

J Med Chem. 2016 Sep 8;59(17):7901-14. doi: 10.1021/acs.jmedchem.6b00703. Epub 2016 Aug 19.

PMID:
27502700
9.

An alternative route to the arylvinyltriazole nucleosides.

Chudinov MV, Prutkov AN, Matveev AV, Grebenkina LE, Konstantinova ID, Berezovskaya YV.

Bioorg Med Chem Lett. 2016 Jul 15;26(14):3223-3225. doi: 10.1016/j.bmcl.2016.05.072. Epub 2016 May 26.

PMID:
27262598
10.

Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides.

Fateev IV, Kharitonova MI, Antonov KV, Konstantinova ID, Stepanenko VN, Esipov RS, Seela F, Temburnikar KW, Seley-Radtke KL, Stepchenko VA, Sokolov YA, Miroshnikov AI, Mikhailopulo IA.

Chemistry. 2015 Sep 14;21(38):13401-19. doi: 10.1002/chem.201501334. Epub 2015 Jul 31.

PMID:
26230190
11.

[Optimization of modern conservative therapy of micropenis in hypogonadal men].

Petrovich RIu, Sokoll'shchik MM, Tiuzikov IA, Konstantinova IV, Astakhova MA.

Urologiia. 2014 Nov-Dec;(6):82-7. Russian.

PMID:
25799733
12.

A functional analysis of Wnt inducible signalling pathway protein -1 (WISP-1/CCN4).

Stephens S, Palmer J, Konstantinova I, Pearce A, Jarai G, Day E.

J Cell Commun Signal. 2015 Mar;9(1):63-72. doi: 10.1007/s12079-015-0267-9. Epub 2015 Feb 6.

13.

The chemoenzymatic synthesis of clofarabine and related 2'-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition by E. coli nucleoside phosphorylases.

Fateev IV, Antonov KV, Konstantinova ID, Muravyova TI, Seela F, Esipov RS, Miroshnikov AI, Mikhailopulo IA.

Beilstein J Org Chem. 2014 Jul 22;10:1657-69. doi: 10.3762/bjoc.10.173. eCollection 2014.

14.

The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza A virus resistant to rimantadine (amantadine) in vitro and in vivo.

Deryabin PG, Galegov GA, Konstantinova ID, Muzyka IS, Miroshnikov AI, L'vov DK.

Dokl Biochem Biophys. 2014 Mar;455(1):80-3. doi: 10.1134/S1607672914020100. Epub 2014 May 3. No abstract available.

PMID:
24795106
15.

[The structure of urological disorders in athletes].

Shirshov VN, Doronchuk DN, Oblonkov VIu, Shatirishvili OK, Konstantinova IM, Lebedev IuI, Charushina IM.

Urologiia. 2013 Jul-Aug;(4):24-6. Russian.

PMID:
24159760
16.

[The arsenolysis reaction in the biotechnological method of synthesis of the ribavirin. Inhibition of reproduction of influenza A virus with the combination of ribavirin and ozeltamivir in experiments in vitro and in vivo].

Konstantinova ID, Fateev IV, Galegov GA, Deriabin PG, Botikov AG, Muzyka IS, L'vov DK, Miroshnikov AI.

Bioorg Khim. 2013 Sep-Oct;39(5):594-603. Russian.

PMID:
25702418
17.

[Nucleosides of 1,2,4-triazole: potentialities and restrictions of chemo-enzymatic method for synthesis].

Konstantinova ID, Chudinov MV, Fateev IV, Matveev AV, Zhurilo NI, Shvets VI, Miroshnikov AI.

Bioorg Khim. 2013 Jan-Feb;39(1):61-80. Russian.

PMID:
23844508
18.

Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.

Ciuclan L, Hussey MJ, Burton V, Good R, Duggan N, Beach S, Jones P, Fox R, Clay I, Bonneau O, Konstantinova I, Pearce A, Rowlands DJ, Jarai G, Westwick J, MacLean MR, Thomas M.

Am J Respir Crit Care Med. 2013 Jan 1;187(1):78-89. doi: 10.1164/rccm.201206-1028OC. Epub 2012 Oct 18.

PMID:
23087024
19.

26S proteasome exhibits endoribonuclease activity controlled by extra-cellular stimuli.

Kulichkova VA, Tsimokha AS, Fedorova OA, Moiseeva TN, Bottril A, Lezina L, Gauze LN, Konstantinova IM, Mittenberg AG, Barlev NA.

Cell Cycle. 2010 Feb 15;9(4):840-9. Epub 2010 Mar 2.

PMID:
20139718
20.

Exogenous 26S proteasomes can enter living cells to influence gene expression in the recipient cells.

Kulichkova VA, Vatazhok YY, Tsimokha AS, Kozhukharova IV, Ermolaeva YB, Evteeva IN, Mittenberg AG, Gause LN, Konstantinova IM.

Dokl Biol Sci. 2008 Nov-Dec;423:464-8. No abstract available.

PMID:
19213438

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