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Items: 1 to 20 of 61

1.

A vitamin-C-derived DNA modification catalysed by an algal TET homologue.

Xue JH, Chen GD, Hao F, Chen H, Fang Z, Chen FF, Pang B, Yang QL, Wei X, Fan QQ, Xin C, Zhao J, Deng X, Wang BA, Zhang XJ, Chu Y, Tang H, Yin H, Ma W, Chen L, Ding J, Weinhold E, Kohli RM, Liu W, Zhu ZJ, Huang K, Tang H, Xu GL.

Nature. 2019 May;569(7757):581-585. doi: 10.1038/s41586-019-1160-0. Epub 2019 May 1.

PMID:
31043749
2.

Improving the Fluorescent Probe Acridonylalanine Through a Combination of Theory and Experiment.

Sungwienwong I, Ferrie JJ, Jun JV, Liu C, Barrett TM, Hostetler ZM, Ieda N, Hendricks A, Muthusamy AK, Kohli RM, Chenoweth DM, Petersson GA, Petersson EJ.

J Phys Org Chem. 2018 Aug;31(8). pii: e3813. doi: 10.1002/poc.3813. Epub 2018 Feb 22.

3.

Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response.

Selwood T, Larsen BJ, Mo CY, Culyba MJ, Hostetler ZM, Kohli RM, Reitz AB, Baugh SDP.

Front Microbiol. 2018 Dec 18;9:2961. doi: 10.3389/fmicb.2018.02961. eCollection 2018.

4.

Exploiting Substrate Promiscuity To Develop Activity-Based Probes for Ten-Eleven Translocation Family Enzymes.

Ghanty U, DeNizio JE, Liu MY, Kohli RM.

J Am Chem Soc. 2018 Dec 19;140(50):17329-17332. doi: 10.1021/jacs.8b04722. Epub 2018 Dec 11.

PMID:
30518204
5.

The SOS Response Mediates Sustained Colonization of the Mammalian Gut.

Samuels AN, Roggiani M, Zhu J, Goulian M, Kohli RM.

Infect Immun. 2019 Jan 24;87(2). pii: e00711-18. doi: 10.1128/IAI.00711-18. Print 2019 Feb.

6.

How reliable and valid are the self-reports of sexual behavior among HIV discordant couples in Pune, INDIA.

Kohli RM, Mehendale S, Brahme R, Bollinger B, Chidrawar S, Ghate M, Joglekar N, Sahay S.

Psychol Health Med. 2018 Jan - Dec;23(sup1):1333-1340. doi: 10.1080/13548506.2018.1499943.

PMID:
30486669
7.

Selectivity and Promiscuity in TET-Mediated Oxidation of 5-Methylcytosine in DNA and RNA.

DeNizio JE, Liu MY, Leddin EM, Cisneros GA, Kohli RM.

Biochemistry. 2019 Feb 5;58(5):411-421. doi: 10.1021/acs.biochem.8b00912. Epub 2018 Nov 14.

PMID:
30387995
8.

OGT binds a conserved C-terminal domain of TET1 to regulate TET1 activity and function in development.

Hrit J, Goodrich L, Li C, Wang BA, Nie J, Cui X, Martin EA, Simental E, Fernandez J, Liu MY, Nery JR, Castanon R, Kohli RM, Tretyakova N, He C, Ecker JR, Goll M, Panning B.

Elife. 2018 Oct 16;7. pii: e34870. doi: 10.7554/eLife.34870.

9.

Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.

Schutsky EK, DeNizio JE, Hu P, Liu MY, Nabel CS, Fabyanic EB, Hwang Y, Bushman FD, Wu H, Kohli RM.

Nat Biotechnol. 2018 Oct 8. doi: 10.1038/nbt.4204. [Epub ahead of print]

10.

Systematic Evaluation of Soluble Protein Expression Using a Fluorescent Unnatural Amino Acid Reveals No Reliable Predictors of Tolerability.

Hostetler ZM, Ferrie JJ, Bornstein MR, Sungwienwong I, Petersson EJ, Kohli RM.

ACS Chem Biol. 2018 Oct 19;13(10):2855-2861. doi: 10.1021/acschembio.8b00696. Epub 2018 Sep 20.

PMID:
30216041
11.

Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network.

Culyba MJ, Kubiak JM, Mo CY, Goulian M, Kohli RM.

PLoS Genet. 2018 Jun 1;14(6):e1007405. doi: 10.1371/journal.pgen.1007405. eCollection 2018 Jun.

12.

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.

Fraietta JA, Nobles CL, Sammons MA, Lundh S, Carty SA, Reich TJ, Cogdill AP, Morrissette JJD, DeNizio JE, Reddy S, Hwang Y, Gohil M, Kulikovskaya I, Nazimuddin F, Gupta M, Chen F, Everett JK, Alexander KA, Lin-Shiao E, Gee MH, Liu X, Young RM, Ambrose D, Wang Y, Xu J, Jordan MS, Marcucci KT, Levine BL, Garcia KC, Zhao Y, Kalos M, Porter DL, Kohli RM, Lacey SF, Berger SL, Bushman FD, June CH, Melenhorst JJ.

Nature. 2018 Jun;558(7709):307-312. doi: 10.1038/s41586-018-0178-z. Epub 2018 May 30.

13.

Harnessing natural DNA modifying activities for editing of the genome and epigenome.

DeNizio JE, Schutsky EK, Berrios KN, Liu MY, Kohli RM.

Curr Opin Chem Biol. 2018 Aug;45:10-17. doi: 10.1016/j.cbpa.2018.01.016. Epub 2018 Feb 13. Review.

14.

Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.

Mo CY, Culyba MJ, Selwood T, Kubiak JM, Hostetler ZM, Jurewicz AJ, Keller PM, Pope AJ, Quinn A, Schneck J, Widdowson KL, Kohli RM.

ACS Infect Dis. 2018 Mar 9;4(3):349-359. doi: 10.1021/acsinfecdis.7b00122. Epub 2018 Jan 8.

15.

Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.

Wang F, Zahid OK, Swain BE, Parsonage D, Hollis T, Harvey S, Perrino FW, Kohli RM, Taylor EW, Hall AR.

Nano Lett. 2017 Nov 8;17(11):7110-7116. doi: 10.1021/acs.nanolett.7b03911. Epub 2017 Oct 5.

16.

A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage.

Kubiak JM, Culyba MJ, Liu MY, Mo CY, Goulian M, Kohli RM.

ACS Synth Biol. 2017 Nov 17;6(11):2067-2076. doi: 10.1021/acssynbio.7b00108. Epub 2017 Sep 1.

17.

APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA.

Schutsky EK, Nabel CS, Davis AKF, DeNizio JE, Kohli RM.

Nucleic Acids Res. 2017 Jul 27;45(13):7655-7665. doi: 10.1093/nar/gkx345.

18.

Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection.

Sungwienwong I, Hostetler ZM, Blizzard RJ, Porter JJ, Driggers CM, Mbengi LZ, Villegas JA, Speight LC, Saven JG, Perona JJ, Kohli RM, Mehl RA, Petersson EJ.

Org Biomol Chem. 2017 May 3;15(17):3603-3610. doi: 10.1039/c7ob00582b.

19.

DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia.

Nabel CS, DeNizio JE, Carroll M, Kohli RM.

Biochemistry. 2017 Apr 25;56(16):2166-2169. doi: 10.1021/acs.biochem.7b00208. Epub 2017 Apr 12.

20.

Mechanisms for targeted, purposeful mutation revealed in an APOBEC-DNA complex.

Schutsky EK, Hostetler ZM, Kohli RM.

Nat Struct Mol Biol. 2017 Feb 6;24(2):97-98. doi: 10.1038/nsmb.3373. No abstract available.

PMID:
28169999

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