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Items: 1 to 20 of 65

1.

Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties.

Hirst J, Pathak HB, Hyter S, Pessetto ZY, Ly T, Graw S, Koestler DC, Krieg AJ, Roby KF, Godwin AK.

Cancer Res. 2018 Jun 11. pii: canres.3993.2017. doi: 10.1158/0008-5472.CAN-17-3993. [Epub ahead of print]

PMID:
29891506
2.

An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray.

Salas LA, Koestler DC, Butler RA, Hansen HM, Wiencke JK, Kelsey KT, Christensen BC.

Genome Biol. 2018 May 29;19(1):64. doi: 10.1186/s13059-018-1448-7.

3.

Association of Neutrophil-to-Lymphocyte Ratio With Mortality and Cardiovascular Disease in the Jackson Heart Study and Modification by the Duffy Antigen Variant.

Kim S, Eliot M, Koestler DC, Wu WC, Kelsey KT.

JAMA Cardiol. 2018 May 2. doi: 10.1001/jamacardio.2018.1042. [Epub ahead of print]

PMID:
29801037
4.

Developing a genetic signature to predict drug response in ovarian cancer.

Hyter S, Hirst J, Pathak H, Pessetto ZY, Koestler DC, Raghavan R, Pei D, Godwin AK.

Oncotarget. 2017 Dec 26;9(19):14828-14848. doi: 10.18632/oncotarget.23663. eCollection 2018 Mar 13.

5.

Mediation analysis of alcohol consumption, DNA methylation, and epithelial ovarian cancer.

Wu D, Yang H, Winham SJ, Natanzon Y, Koestler DC, Luo T, Fridley BL, Goode EL, Zhang Y, Cui Y.

J Hum Genet. 2018 Mar;63(3):339-348. doi: 10.1038/s10038-017-0385-8. Epub 2018 Jan 10.

PMID:
29321518
6.

Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver-Dependent Manner.

Brinker AE, Vivian CJ, Koestler DC, Tsue TT, Jensen RA, Welch DR.

Cancer Res. 2017 Dec 15;77(24):6941-6949. doi: 10.1158/0008-5472.CAN-17-2194. Epub 2017 Oct 25.

PMID:
29070615
7.

Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism.

Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C.

J Biol Chem. 2017 Sep 8;292(36):14940-14962. doi: 10.1074/jbc.M117.797944. Epub 2017 Jul 24.

PMID:
28739801
8.

Mitochondrial Genomic Backgrounds Affect Nuclear DNA Methylation and Gene Expression.

Vivian CJ, Brinker AE, Graw S, Koestler DC, Legendre C, Gooden GC, Salhia B, Welch DR.

Cancer Res. 2017 Nov 15;77(22):6202-6214. doi: 10.1158/0008-5472.CAN-17-1473. Epub 2017 Jun 29.

PMID:
28663334
9.

Maternal serum PFOA concentration and DNA methylation in cord blood: A pilot study.

Kingsley SL, Kelsey KT, Butler R, Chen A, Eliot MN, Romano ME, Houseman A, Koestler DC, Lanphear BP, Yolton K, Braun JM.

Environ Res. 2017 Oct;158:174-178. doi: 10.1016/j.envres.2017.06.013. Epub 2017 Jun 20.

PMID:
28645023
10.

The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression.

Winterbottom EF, Koestler DC, Fei DL, Wika E, Capobianco AJ, Marsit CJ, Karagas MR, Robbins DJ.

Environ Health. 2017 Jun 14;16(1):59. doi: 10.1186/s12940-017-0267-8.

11.

Integrative epigenetic and genetic pan-cancer somatic alteration portraits.

Salas LA, Johnson KC, Koestler DC, O'Sullivan DE, Christensen BC.

Epigenetics. 2017 Jul 3;12(7):561-574. doi: 10.1080/15592294.2017.1319043. Epub 2017 Apr 20.

12.

Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses.

Zheng SC, Beck S, Jaffe AE, Koestler DC, Hansen KD, Houseman AE, Irizarry RA, Teschendorff AE.

Nat Methods. 2017 Feb 28;14(3):216-217. doi: 10.1038/nmeth.4187. No abstract available.

PMID:
28245219
13.

Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.

Wiencke JK, Koestler DC, Salas LA, Wiemels JL, Roy RP, Hansen HM, Rice T, McCoy LS, Bracci PM, Molinaro AM, Kelsey KT, Wrensch MR, Christensen BC.

Clin Epigenetics. 2017 Feb 2;9:10. doi: 10.1186/s13148-017-0316-8. eCollection 2017.

14.

DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio: An Epigenetic Tool to Explore Cancer Inflammation and Outcomes.

Koestler DC, Usset J, Christensen BC, Marsit CJ, Karagas MR, Kelsey KT, Wiencke JK.

Cancer Epidemiol Biomarkers Prev. 2017 Mar;26(3):328-338. doi: 10.1158/1055-9965.EPI-16-0461. Epub 2016 Dec 13.

15.

Enlarged leukocyte referent libraries can explain additional variance in blood-based epigenome-wide association studies.

Kim S, Eliot M, Koestler DC, Houseman EA, Wetmur JG, Wiencke JK, Kelsey KT.

Epigenomics. 2016 Sep;8(9):1185-92. doi: 10.2217/epi-2016-0037. Epub 2016 Aug 16.

16.

Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.

O'Sullivan DE, Johnson KC, Skinner L, Koestler DC, Christensen BC.

Epigenetics. 2016 May 3;11(5):344-53. doi: 10.1080/15592294.2016.1168673. Epub 2016 Apr 12.

17.

Prenatal Programming of Infant Neurobehaviour in a Healthy Population.

Appleton AA, Murphy MA, Koestler DC, Lesseur C, Paquette AG, Padbury JF, Lester BM, Marsit CJ.

Paediatr Perinat Epidemiol. 2016 Jul;30(4):367-75. doi: 10.1111/ppe.12294. Epub 2016 Mar 23.

18.

Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL).

Koestler DC, Jones MJ, Usset J, Christensen BC, Butler RA, Kobor MS, Wiencke JK, Kelsey KT.

BMC Bioinformatics. 2016 Mar 8;17:120. doi: 10.1186/s12859-016-0943-7.

19.

CpG island methylation profile in non-invasive oral rinse samples is predictive of oral and pharyngeal carcinoma.

Langevin SM, Eliot M, Butler RA, Cheong A, Zhang X, McClean MD, Koestler DC, Kelsey KT.

Clin Epigenetics. 2015 Dec 3;7:125. doi: 10.1186/s13148-015-0160-7. eCollection 2015.

20.

GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.

Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ.

EBioMedicine. 2015 May 1;2(6):536-43. doi: 10.1016/j.ebiom.2015.04.019. eCollection 2015 Jun.

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