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Items: 1 to 20 of 200

1.

Towards the structure of the TIR-domain signalosome.

Nimma S, Ve T, Williams SJ, Kobe B.

Curr Opin Struct Biol. 2017 Jan 13;43:122-130. doi: 10.1016/j.sbi.2016.12.014. [Epub ahead of print] Review.

PMID:
28092811
2.

GMP Synthase is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.

Chitty JL, Tatzenko TL, Williams SJ, Koh YQ, Corfield EC, Butler MS, Robertson AA, Cooper MA, Kappler U, Kobe B, Fraser JA.

J Biol Chem. 2017 Jan 6. pii: jbc.M116.767533. doi: 10.1074/jbc.M116.767533. [Epub ahead of print]

3.

Structure and Function of the TIR Domain from the Grape NLR Protein RPV1.

Williams SJ, Yin L, Foley G, Casey LW, Outram MA, Ericsson DJ, Lu J, Boden M, Dry IB, Kobe B.

Front Plant Sci. 2016 Dec 8;7:1850. doi: 10.3389/fpls.2016.01850.

4.

The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins.

Casey LW, Lavrencic P, Bentham AR, Cesari S, Ericsson DJ, Croll T, Turk D, Anderson PA, Mark AE, Dodds PN, Mobli M, Kobe B, Williams SJ.

Proc Natl Acad Sci U S A. 2016 Oct 17. pii: 201609922. [Epub ahead of print]

PMID:
27791121
5.

Wheat PR-1 proteins are targeted by necrotrophic pathogen effector proteins.

Breen S, Williams SJ, Winterberg B, Kobe B, Solomon PS.

Plant J. 2016 Oct;88(1):13-25. doi: 10.1111/tpj.13228.

PMID:
27258471
6.

Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans.

Blundell RD, Williams SJ, Arras SD, Chitty JL, Blake KL, Ericsson DJ, Tibrewal N, Rohr J, Koh YQ, Kappler U, Robertson AA, Butler MS, Cooper MA, Kobe B, Fraser JA.

ACS Infect Dis. 2016 Sep 9;2(9):651-663.

PMID:
27759389
7.

Animal NLRs provide structural insights into plant NLR function.

Bentham A, Burdett H, Anderson PA, Williams SJ, Kobe B.

Ann Bot. 2016 Aug 25. pii: mcw171. [Epub ahead of print] Review.

PMID:
27562749
8.

Prediction of kinase-specific phosphorylation sites through an integrative model of protein context and sequence.

Patrick R, Horin C, Kobe B, Cao KA, Bodén M.

Biochim Biophys Acta. 2016 Nov;1864(11):1599-608. doi: 10.1016/j.bbapap.2016.08.001.

PMID:
27507704
9.

Multiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell Death.

Schreiber KJ, Bentham A, Williams SJ, Kobe B, Staskawicz BJ.

PLoS Pathog. 2016 Jul 18;12(7):e1005769. doi: 10.1371/journal.ppat.1005769.

10.

Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.

Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B.

Nucleic Acids Res. 2016 Aug 19;44(14):6981-93. doi: 10.1093/nar/gkw543.

11.

Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner.

Jung JY, Gleave Parson M, Kraft JD, Lyda L, Kobe B, Davis C, Robinson J, Peña MM, Robinson CM.

Immunology. 2016 Sep;149(1):35-47. doi: 10.1111/imm.12625.

PMID:
27238498
12.

Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-α.

Chang CW, Couñago RM, Williams SJ, Bodén M, Kobe B.

Traffic. 2016 Jun;17(6):704. doi: 10.1111/tra.12395. No abstract available.

13.

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target.

Ullah MO, Sweet MJ, Mansell A, Kellie S, Kobe B.

J Leukoc Biol. 2016 Jul;100(1):27-45. doi: 10.1189/jlb.2RI1115-531R. Review.

PMID:
27162325
14.

Protein crystal screening and characterization for serial femtosecond nanocrystallography.

Darmanin C, Strachan J, Adda CG, Ve T, Kobe B, Abbey B.

Sci Rep. 2016 May 3;6:25345. doi: 10.1038/srep25345.

15.

Production of small cysteine-rich effector proteins in Escherichia coli for structural and functional studies.

Zhang X, Nguyen N, Breen S, Outram MA, Dodds PN, Kobe B, Solomon PS, Williams SJ.

Mol Plant Pathol. 2017 Jan;18(1):141-151. doi: 10.1111/mpp.12385.

PMID:
26915457
16.

Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution - a potential target for anti-tuberculosis drug discovery.

Lv Y, Kandale A, Wun SJ, McGeary RP, Williams SJ, Kobe B, Sieber V, Schembri MA, Schenk G, Guddat LW.

FEBS J. 2016 Apr;283(7):1184-96. doi: 10.1111/febs.13672.

PMID:
26876563
17.

Temperature-Dependent Gentamicin Resistance of Francisella tularensis is Mediated by Uptake Modulation.

Loughman K, Hall J, Knowlton S, Sindeldecker D, Gilson T, Schmitt DM, Birch JW, Gajtka T, Kobe BN, Florjanczyk A, Ingram J, Bakshi CS, Horzempa J.

Front Microbiol. 2016 Jan 28;7:37. doi: 10.3389/fmicb.2016.00037.

18.

Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.

Barros AC, Takeda AA, Dreyer TR, Velazquez-Campoy A, Kobe B, Fontes MR.

J Mol Biol. 2016 May 22;428(10 Pt A):2120-31. doi: 10.1016/j.jmb.2016.01.019.

PMID:
26812207
19.

Comparative Analysis of the Flax Immune Receptors L6 and L7 Suggests an Equilibrium-Based Switch Activation Model.

Bernoux M, Burdett H, Williams SJ, Zhang X, Chen C, Newell K, Lawrence GJ, Kobe B, Ellis JG, Anderson PA, Dodds PN.

Plant Cell. 2016 Jan;28(1):146-59. doi: 10.1105/tpc.15.00303.

20.

Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA.

Luo Z, Morey JR, McDevitt CA, Kobe B.

Acta Crystallogr F Struct Biol Commun. 2015 Dec;71(Pt 12):1459-64. doi: 10.1107/S2053230X15021330.

PMID:
26625286
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