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Items: 1 to 20 of 55

1.

Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2016 Nov 16;17(12):1479. doi: 10.1038/ni1216-1479c. No abstract available.

PMID:
27849203
2.

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581.

PMID:
27721430
3.

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.

Yángüez E, García-Culebras A, Frau A, Llompart C, Knobeloch KP, Gutierrez-Erlandsson S, García-Sastre A, Esteban M, Nieto A, Guerra S.

PLoS Pathog. 2016 Oct 13;12(10):e1005969. doi: 10.1371/journal.ppat.1005969.

4.

Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator.

Cerikan B, Shaheen R, Colo GP, Gläßer C, Hata S, Knobeloch KP, Alkuraya FS, Fässler R, Schiebel E.

Dev Cell. 2016 Oct 10;39(1):28-43. doi: 10.1016/j.devcel.2016.08.020.

PMID:
27693507
5.

Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.

Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Günther C, Müller W, Knobeloch KP, Prinz M, Roers A, Behrendt R.

J Immunol. 2016 Sep 15;197(6):2157-66. doi: 10.4049/jimmunol.1600722.

PMID:
27511730
6.

A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development.

Klein-Hessling S, Rudolf R, Muhammad K, Knobeloch KP, Maqbool MA, Cauchy P, Andrau JC, Avots A, Talora C, Ellenrieder V, Screpanti I, Serfling E, Patra AK.

Nat Commun. 2016 Jun 17;7:11841. doi: 10.1038/ncomms11841.

7.

USP8--Another DUB in the T cell club.

Dufner A, Knobeloch KP.

Cell Cycle. 2015;14(24):3775-6. doi: 10.1080/15384101.2015.1105698. No abstract available.

8.

NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice.

Busch R, Murti K, Liu J, Patra AK, Muhammad K, Knobeloch KP, Lichtinger M, Bonifer C, Wörtge S, Waisman A, Reifenberg K, Ellenrieder V, Serfling E, Avots A.

Eur J Immunol. 2016 Mar;46(3):634-46. doi: 10.1002/eji.201545925.

PMID:
26631626
9.

The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice.

Deák VA, Skroblin P, Dittmayer C, Knobeloch KP, Bachmann S, Klussmann E.

J Biol Chem. 2016 Jan 8;291(2):681-90. doi: 10.1074/jbc.M115.701177.

10.

ISG15 counteracts Listeria monocytogenes infection.

Radoshevich L, Impens F, Ribet D, Quereda JJ, Nam Tham T, Nahori MA, Bierne H, Dussurget O, Pizarro-Cerdá J, Knobeloch KP, Cossart P.

Elife. 2015 Aug 11;4. doi: 10.7554/eLife.06848.

11.

The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.

Dufner A, Kisser A, Niendorf S, Basters A, Reissig S, Schönle A, Aichem A, Kurz T, Schlosser A, Yablonski D, Groettrup M, Buch T, Waisman A, Schamel WW, Prinz M, Knobeloch KP.

Nat Immunol. 2015 Sep;16(9):950-60. doi: 10.1038/ni.3230.

PMID:
26214742
12.

The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.

Albert GI, Schell C, Kirschner KM, Schäfer S, Naumann R, Müller A, Kretz O, Kuropka B, Girbig M, Hübner N, Krause E, Scholz H, Huber TB, Knobeloch KP, Freund C.

J Mol Cell Biol. 2015 Oct;7(5):402-14. doi: 10.1093/jmcb/mjv039.

PMID:
26082520
13.

USP18 lack in microglia causes destructive interferonopathy of the mouse brain.

Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, Basters A, Staszewski O, Brendecke SM, Spiess A, Tay TL, Kreutz C, Timmer J, Mancini GM, Blank T, Fritz G, Biber K, Lang R, Malo D, Merkler D, Heikenwälder M, Knobeloch KP, Prinz M.

EMBO J. 2015 Jun 12;34(12):1612-29. doi: 10.15252/embj.201490791.

14.

ISG15 uncut: Dissecting enzymatic and non-enzymatic functions of USP18 in vivo.

Ketscher L, Knobeloch KP.

Cytokine. 2015 Dec;76(2):569-71. doi: 10.1016/j.cyto.2015.03.006.

PMID:
25805508
15.

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance.

Ketscher L, Hannß R, Morales DJ, Basters A, Guerra S, Goldmann T, Hausmann A, Prinz M, Naumann R, Pekosz A, Utermöhlen O, Lenschow DJ, Knobeloch KP.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1577-82. doi: 10.1073/pnas.1412881112.

16.

Ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) in host defense against heart failure in a mouse model of virus-induced cardiomyopathy.

Rahnefeld A, Klingel K, Schuermann A, Diny NL, Althof N, Lindner A, Bleienheuft P, Savvatis K, Respondek D, Opitz E, Ketscher L, Sauter M, Seifert U, Tschöpe C, Poller W, Knobeloch KP, Voigt A.

Circulation. 2014 Oct 28;130(18):1589-600. doi: 10.1161/CIRCULATIONAHA.114.009847.

17.

Genetic targeting of microglia.

Wieghofer P, Knobeloch KP, Prinz M.

Glia. 2015 Jan;63(1):1-22. doi: 10.1002/glia.22727. Review.

PMID:
25132502
18.

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.

Basters A, Geurink PP, El Oualid F, Ketscher L, Casutt MS, Krause E, Ovaa H, Knobeloch KP, Fritz G.

FEBS J. 2014 Apr;281(7):1918-28. doi: 10.1111/febs.12754.

19.

STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.

Begitt A, Droescher M, Meyer T, Schmid CD, Baker M, Antunes F, Knobeloch KP, Owen MR, Naumann R, Decker T, Vinkemeier U.

Nat Immunol. 2014 Feb;15(2):168-76. doi: 10.1038/ni.2794. Erratum in: Nat Immunol. 2014 Nov;15(11):1090.

PMID:
24413774
20.

HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia.

Troilo A, Alexander I, Muehl S, Jaramillo D, Knobeloch KP, Krek W.

EMBO Rep. 2014 Jan;15(1):77-85. doi: 10.1002/embr.201337688.

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