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Items: 1 to 20 of 57


Aicardi syndrome: epilepsy surgery as a palliative treatment option for selected patients and pathological findings.

Podkorytova I, Gupta A, Wyllie E, Moosa A, Bingaman W, Prayson R, Knight EM.

Epileptic Disord. 2016 Dec 1;18(4):431-439. doi: 10.1684/epd.2016.0872.


Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes.

Knight EM, Kim SH, Kottwitz JC, Hatami A, Albay R, Suzuki A, Lublin A, Alberini CM, Klein WL, Szabo P, Relkin NR, Ehrlich M, Glabe CG, Gandy S, Steele JW.

Neurol Neuroimmunol Neuroinflamm. 2016 May 10;3(3):e237. doi: 10.1212/NXI.0000000000000237. eCollection 2016 Jun.


Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.

Knight EM, Ruiz HH, Kim SH, Harte JC, Hsieh W, Glabe C, Klein WL, Attie AD, Buettner C, Ehrlich ME, Gandy S.

Acta Neuropathol Commun. 2016 Feb 25;4:16. doi: 10.1186/s40478-016-0282-y.


WAVEFORM WINDOW #32: 14 and 6 Hz Positive Spikes: A Normal Variant that Could be Mistaken as Epileptiform.

Eber C, de Bruyn G, Knight EM.

Neurodiagn J. 2015 Sep;55(3):204-10. No abstract available.


Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ.

Knight EM, Williams HN, Stevens AC, Kim SH, Kottwitz JC, Morant AD, Steele JW, Klein WL, Yanagisawa K, Boyd RE, Lockhart DJ, Sjoberg ER, Ehrlich ME, Wustman BA, Gandy S.

Mol Psychiatry. 2015 Feb;20(1):109-17. doi: 10.1038/mp.2014.135. Epub 2014 Oct 28.


Paroxysmal non-epileptic events in infants and toddlers: A phenomenologic analysis.

Chen L, Knight EM, Tuxhorn I, Shahid A, Lüders HO.

Psychiatry Clin Neurosci. 2015 Jun;69(6):351-9. doi: 10.1111/pcn.12245. Epub 2014 Dec 1.


Immunomodulation and AD--down but not out.

Knight EM, Gandy S.

J Clin Immunol. 2014 Jul;34 Suppl 1:S70-3. doi: 10.1007/s10875-014-0039-y. Epub 2014 Apr 30. Review.


High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology.

Knight EM, Martins IV, Gümüsgöz S, Allan SM, Lawrence CB.

Neurobiol Aging. 2014 Aug;35(8):1821-32. doi: 10.1016/j.neurobiolaging.2014.02.010. Epub 2014 Feb 15.


Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states.

Cho BK, Kim D, Knight EM, Zengler K, Palsson BO.

BMC Biol. 2014 Jan 24;12:4. doi: 10.1186/1741-7007-12-4.


Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model.

Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight EM, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich ME, Robakis NK, Gandy SE, Cai D.

J Biol Chem. 2013 Nov 1;288(44):32050-63. doi: 10.1074/jbc.M113.504365. Epub 2013 Sep 19.


Age-related changes in core body temperature and activity in triple-transgenic Alzheimer's disease (3xTgAD) mice.

Knight EM, Brown TM, Gümüsgöz S, Smith JC, Waters EJ, Allan SM, Lawrence CB.

Dis Model Mech. 2013 Jan;6(1):160-70. doi: 10.1242/dmm.010173. Epub 2012 Aug 3.


Gaucher disease: successful treatment of myoclonic status epilepticus with levetiracetam.

Vaca GF, Lenz T, Knight EM, Tuxhorn I.

Epileptic Disord. 2012 Jun;14(2):155-8. doi: 10.1684/epd.2012.0501.


Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide.

Lawrence CB, Brough D, Knight EM.

Dis Model Mech. 2012 Sep;5(5):649-59. doi: 10.1242/dmm.009068. Epub 2012 Feb 10.


Detailing the optimality of photosynthesis in cyanobacteria through systems biology analysis.

Nogales J, Gudmundsson S, Knight EM, Palsson BO, Thiele I.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2678-83. doi: 10.1073/pnas.1117907109. Epub 2012 Jan 30.


Rapid doubling of Alzheimer's amyloid-β40 and 42 levels in brains of mice exposed to a nickel nanoparticle model of air pollution.

Kim SH, Knight EM, Saunders EL, Cuevas AK, Popovech M, Chen LC, Gandy S.

F1000Res. 2012 Dec 21;1:70. doi: 10.12688/f1000research.1-70.v1. eCollection 2012.


Nurse staffing and inpatient hospital mortality.

Knight EM.

N Engl J Med. 2011 Jun 23;364(25):2468-9; author reply 2469. doi: 10.1056/NEJMc1104381#SA2. No abstract available.


Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene.

Charusanti P, Conrad TM, Knight EM, Venkataraman K, Fong NL, Xie B, Gao Y, Palsson BØ.

PLoS Genet. 2010 Nov 4;6(11):e1001186. doi: 10.1371/journal.pgen.1001186.


RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media.

Conrad TM, Frazier M, Joyce AR, Cho BK, Knight EM, Lewis NE, Landick R, Palsson BØ.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20500-5. doi: 10.1073/pnas.0911253107. Epub 2010 Nov 5.


Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease.

Knight EM, Verkhratsky A, Luckman SM, Allan SM, Lawrence CB.

Neurobiol Aging. 2012 Jan;33(1):187-93. doi: 10.1016/j.neurobiolaging.2010.02.003. Epub 2010 Mar 31.


The transcription unit architecture of the Escherichia coli genome.

Cho BK, Zengler K, Qiu Y, Park YS, Knight EM, Barrett CL, Gao Y, Palsson BØ.

Nat Biotechnol. 2009 Nov;27(11):1043-9. doi: 10.1038/nbt.1582. Epub 2009 Nov 1.

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