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Items: 1 to 20 of 83

1.

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.

Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):853-863. doi: 10.1093/gerona/glx177.

PMID:
29905772
2.

Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.

Deepa SS, Pharaoh G, Kinter M, Diaz V, Fok WC, Riddle K, Pulliam D, Hill S, Fischer KE, Soto V, Georgescu C, Wren JD, Viscomi C, Richardson A, Van Remmen H.

Aging Cell. 2018 Apr 25:e12769. doi: 10.1111/acel.12769. [Epub ahead of print]

3.

Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.

Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H.

Redox Biol. 2018 Jul;17:47-58. doi: 10.1016/j.redox.2018.04.004. Epub 2018 Apr 6. No abstract available.

4.

Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice.

Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter C, Kinter M, Szweda LI.

J Biol Chem. 2018 May 4;293(18):6915-6924. doi: 10.1074/jbc.RA117.000268. Epub 2018 Mar 14.

PMID:
29540486
5.

Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance.

Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS.

EMBO Rep. 2018 Mar;19(3). pii: e45009. doi: 10.15252/embr.201745009. Epub 2018 Feb 2.

PMID:
29420235
6.

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes.

Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE.

Mol Metab. 2018 Mar;9:141-155. doi: 10.1016/j.molmet.2018.01.013. Epub 2018 Feb 2.

7.

Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity.

Bockus LB, Matsuzaki S, Vadvalkar SS, Young ZT, Giorgione JR, Newhardt MF, Kinter M, Humphries KM.

J Am Heart Assoc. 2017 Dec 4;6(12). pii: e007159. doi: 10.1161/JAHA.117.007159.

8.

PPARα is essential for retinal lipid metabolism and neuronal survival.

Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, Smith LEH, Ma JX.

BMC Biol. 2017 Nov 28;15(1):113. doi: 10.1186/s12915-017-0451-x.

9.

Photoreceptor glucose metabolism determines normal retinal vascular growth.

Fu Z, Löfqvist CA, Liegl R, Wang Z, Sun Y, Gong Y, Liu CH, Meng SS, Burnim SB, Arellano I, Chouinard MT, Duran R, Poblete A, Cho SS, Akula JD, Kinter M, Ley D, Pupp IH, Talukdar S, Hellström A, Smith LE.

EMBO Mol Med. 2018 Jan;10(1):76-90. doi: 10.15252/emmm.201707966.

10.

Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy.

Masser DR, Otalora L, Clark NW, Kinter MT, Elliott MH, Freeman WM.

J Neurochem. 2017 Dec;143(5):595-608. doi: 10.1111/jnc.14216. Epub 2017 Oct 20.

PMID:
28902411
11.

Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage.

Issa R, Boeving M, Kinter M, Griffin TM.

J Orthop Res. 2018 Feb;36(2):760-769. doi: 10.1002/jor.23728. Epub 2017 Oct 17.

PMID:
28892196
12.

A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice.

Bhaskaran S, Unnikrishnan A, Ranjit R, Qaisar R, Pharaoh G, Matyi S, Kinter M, Deepa SS.

Free Radic Biol Med. 2017 Jul;108:704-714. doi: 10.1016/j.freeradbiomed.2017.04.028. Epub 2017 Apr 26.

PMID:
28455142
13.

Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: ROLE OF MITOCHONDRIAL PYRUVATE CARRIER 2 (MPC2) ACETYLATION.

Vadvalkar SS, Matsuzaki S, Eyster CA, Giorgione JR, Bockus LB, Kinter CS, Kinter M, Humphries KM.

J Biol Chem. 2017 Mar 17;292(11):4423-4433. doi: 10.1074/jbc.M116.753509. Epub 2017 Feb 1.

14.

Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability.

Crewe C, Schafer C, Lee I, Kinter M, Szweda LI.

J Biol Chem. 2017 Jan 6;292(1):305-312. doi: 10.1074/jbc.M116.754127. Epub 2016 Nov 17.

15.

Catalase-dependent H2O2 consumption by cardiac mitochondria and redox-mediated loss in insulin signaling.

Rindler PM, Cacciola A, Kinter M, Szweda LI.

Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1091-H1096. doi: 10.1152/ajpheart.00066.2016. Epub 2016 Sep 9.

16.

Hypoxia induces heart regeneration in adult mice.

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA.

Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31.

PMID:
27798600
17.

Correction: Interaction of G-Protein βγ Complex with Chromatin Modulates GPCR-Dependent Gene Regulation.

Bhatnagar A, Unal H, Jagannathan R, Kaveti S, Duan ZH, Yong S, Vasanji A, Kinter M, Desnoyer R, Karnik SS.

PLoS One. 2016 May 4;11(5):e0155198. doi: 10.1371/journal.pone.0155198. eCollection 2016.

18.

Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis.

Fu Y, Kinter M, Hudson J, Humphries KM, Lane RS, White JR, Hakim M, Pan Y, Verdin E, Griffin TM.

Arthritis Rheumatol. 2016 Aug;68(8):1887-98. doi: 10.1002/art.39618.

19.

Nutrient sensing and utilization: Getting to the heart of metabolic flexibility.

Griffin TM, Humphries KM, Kinter M, Lim HY, Szweda LI.

Biochimie. 2016 May;124:74-83. doi: 10.1016/j.biochi.2015.10.013. Epub 2015 Oct 22. Review.

20.

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging.

Walsh ME, Bhattacharya A, Sataranatarajan K, Qaisar R, Sloane L, Rahman MM, Kinter M, Van Remmen H.

Aging Cell. 2015 Dec;14(6):957-70. doi: 10.1111/acel.12387. Epub 2015 Aug 20.

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