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Items: 1 to 20 of 92

1.

Translational research and the U.S. federal elections.

Kimmelman J, Kesselheim AS.

Sci Transl Med. 2016 Oct 19;8(361):361ed13. No abstract available.

PMID:
27798261
2.

Is Participation in Cancer Phase I Trials Really Therapeutic?

Kimmelman J.

J Clin Oncol. 2017 Jan 10;35(2):135-138. doi: 10.1200/JCO.2016.67.9902. No abstract available.

PMID:
27646944
3.

Accelerated Drug Approval and Health Inequality.

London AJ, Kimmelman J.

JAMA Intern Med. 2016 Jul 1;176(7):883-4. doi: 10.1001/jamainternmed.2016.2534. No abstract available.

PMID:
27295005
4.

Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy.

Mattina J, MacKinnon N, Henderson VC, Fergusson D, Kimmelman J.

Cancer Res. 2016 Aug 15;76(16):4627-36. doi: 10.1158/0008-5472.CAN-15-3455.

PMID:
27261504
5.

Do We Know Whether Researchers and Reviewers are Estimating Risk and Benefit Accurately?

Hey SP, Kimmelman J.

Bioethics. 2016 Oct;30(8):609-17. doi: 10.1111/bioe.12260.

PMID:
27197044
6.

Policy: Global standards for stem-cell research.

Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ.

Nature. 2016 May 19;533(7603):311-3. doi: 10.1038/533311a. No abstract available.

PMID:
27193661
7.

Setting Global Standards for Stem Cell Research and Clinical Translation: TheĀ 2016 ISSCR Guidelines.

Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J.

Stem Cell Reports. 2016 Jun 14;6(6):787-97. doi: 10.1016/j.stemcr.2016.05.001.

8.

Ethical considerations of e-cigarette use for tobacco harm reduction.

Franck C, Filion KB, Kimmelman J, Grad R, Eisenberg MJ.

Respir Res. 2016 May 17;17(1):53. doi: 10.1186/s12931-016-0370-3. Review.

9.

New ISSCR guidelines: clinical translation of stem cell research.

Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ.

Lancet. 2016 May 14;387(10032):1979-81. No abstract available.

PMID:
27179752
10.

SCIENTIFIC COMMUNITY. Confronting stem cell hype.

Caulfield T, Sipp D, Murry CE, Daley GQ, Kimmelman J.

Science. 2016 May 13;352(6287):776-7. doi: 10.1126/science.aaf4620. No abstract available.

PMID:
27174977
11.

How do researchers decide early clinical trials?

Grankvist H, Kimmelman J.

Med Health Care Philos. 2016 Jun;19(2):191-8. doi: 10.1007/s11019-016-9685-6.

PMID:
26833467
12.

Where Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and Stroke.

Holman C, Piper SK, Grittner U, Diamantaras AA, Kimmelman J, Siegerink B, Dirnagl U.

PLoS Biol. 2016 Jan 4;14(1):e1002331. doi: 10.1371/journal.pbio.1002331.

13.

Why clinical translation cannot succeed without failure.

London AJ, Kimmelman J.

Elife. 2015 Nov 24;4:e12844. doi: 10.7554/eLife.12844.

14.

Benefit, Risk, and Outcomes in Drug Development: A Systematic Review of Sunitinib.

Carlisle B, Demko N, Freeman G, Hakala A, MacKinnon N, Ramsay T, Hey S, London AJ, Kimmelman J.

J Natl Cancer Inst. 2015 Nov 7;108(1). pii: djv292. doi: 10.1093/jnci/djv292. Review.

15.

Assessing risk/benefit for trials using preclinical evidence: a proposal.

Kimmelman J, Henderson V.

J Med Ethics. 2016 Jan;42(1):50-3. doi: 10.1136/medethics-2015-102882.

16.

A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib.

Henderson VC, Demko N, Hakala A, MacKinnon N, Federico CA, Fergusson D, Kimmelman J.

Elife. 2015 Oct 13;4:e08351. doi: 10.7554/eLife.08351.

17.

Increasing placebo responses over time in U.S. clinical trials of neuropathic pain.

Tuttle AH, Tohyama S, Ramsay T, Kimmelman J, Schweinhardt P, Bennett GJ, Mogil JS.

Pain. 2015 Dec;156(12):2616-26. doi: 10.1097/j.pain.0000000000000333. Review.

PMID:
26307858
18.

Patient-Funded Trials: Opportunity or Liability?

Wenner DM, Kimmelman J, London AJ.

Cell Stem Cell. 2015 Aug 6;17(2):135-7. doi: 10.1016/j.stem.2015.07.016.

19.

The secret realm of phase I trials in healthy volunteers.

Kimmelman J.

BMJ. 2015 Jun 26;350:h3444. doi: 10.1136/bmj.h3444. No abstract available.

PMID:
26116281
20.

Ethics of Cancer Gene Transfer Clinical Research.

Kimmelman J.

Methods Mol Biol. 2015;1317:263-85. doi: 10.1007/978-1-4939-2727-2_15.

PMID:
26072412
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