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Items: 1 to 20 of 88

1.

Efficacy of phosphodiesterase-4 inhibitors in juvenile Batten disease (CLN3).

Aldrich A, Bosch ME, Fallet R, Odvody J, Burkovetskaya M, Rama Rao KV, Cooper JD, Drack AV, Kielian T.

Ann Neurol. 2016 Nov 2. doi: 10.1002/ana.24815. [Epub ahead of print]

PMID:
27804148
2.

Cyclic di-AMP Released from Staphylococcus aureus Biofilm Induces a Macrophage Type I Interferon Response.

Gries CM, Bruger EL, Moormeier DE, Scherr TD, Waters CM, Kielian T.

Infect Immun. 2016 Nov 18;84(12):3564-3574.

PMID:
27736778
3.

Self-Complementary AAV9 Gene Delivery Partially Corrects Pathology Associated with Juvenile Neuronal Ceroid Lipofuscinosis (CLN3).

Bosch ME, Aldrich A, Fallet R, Odvody J, Burkovetskaya M, Schuberth K, Fitzgerald JA, Foust KD, Kielian T.

J Neurosci. 2016 Sep 14;36(37):9669-82. doi: 10.1523/JNEUROSCI.1635-16.2016.

PMID:
27629717
4.

Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia.

Sun K, Yajjala VK, Bauer C, Talmon GA, Fischer KJ, Kielian T, Metzger DW.

J Exp Med. 2016 Aug 22;213(9):1851-64. doi: 10.1084/jem.20150514.

PMID:
27526712
5.

Infectious Dose Dictates the Host Response during Staphylococcus aureus Orthopedic-Implant Biofilm Infection.

Vidlak D, Kielian T.

Infect Immun. 2016 Jun 23;84(7):1957-65. doi: 10.1128/IAI.00117-16.

PMID:
27091926
6.

Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis.

Geraets RD, Koh Sy, Hastings ML, Kielian T, Pearce DA, Weimer JM.

Orphanet J Rare Dis. 2016 Apr 16;11:40. doi: 10.1186/s13023-016-0414-2. Review.

7.

Resistance to Acute Macrophage Killing Promotes Airway Fitness of Prevalent Community-Acquired Staphylococcus aureus Strains.

Yajjala VK, Thomas VC, Bauer C, Scherr TD, Fischer KJ, Fey PD, Bayles KW, Kielian T, Sun K.

J Immunol. 2016 May 15;196(10):4196-203. doi: 10.4049/jimmunol.1600081.

PMID:
27053759
8.

Multifaceted roles of neuroinflammation: the need to consider both sides of the coin.

Kielian T.

J Neurochem. 2016 Jan;136 Suppl 1:5-9. doi: 10.1111/jnc.13530. Review. No abstract available.

PMID:
26806370
9.

Neuroinflammatory paradigms in lysosomal storage diseases.

Bosch ME, Kielian T.

Front Neurosci. 2015 Oct 30;9:417. doi: 10.3389/fnins.2015.00417. Review.

10.

Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammation.

Rama Rao KV, Kielian T.

Clin Exp Neuroimmunol. 2015 Aug;6(3):245-263.

11.

MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment.

Poole JA, Wyatt TA, Romberger DJ, Staab E, Simet S, Reynolds SJ, Sisson JH, Kielian T.

Respir Res. 2015 Sep 16;16:111. doi: 10.1186/s12931-015-0272-9.

12.

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin.

Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T.

MBio. 2015 Aug 25;6(4). pii: e01021-15. doi: 10.1128/mBio.01021-15.

13.
14.

IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection.

Heim CE, Vidlak D, Scherr TD, Hartman CW, Garvin KL, Kielian T.

J Immunol. 2015 Apr 15;194(8):3861-72. doi: 10.4049/jimmunol.1402689.

15.

Rot is a key regulator of Staphylococcus aureus biofilm formation.

Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR.

Mol Microbiol. 2015 Apr;96(2):388-404. doi: 10.1111/mmi.12943.

16.

Hemichannels in neurodegenerative diseases: is there a link to pathology?

Bosch M, Kielian T.

Front Cell Neurosci. 2014 Aug 20;8:242. doi: 10.3389/fncel.2014.00242.

17.

Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds.

Wang G, Hanke ML, Mishra B, Lushnikova T, Heim CE, Chittezham Thomas V, Bayles KW, Kielian T.

ACS Chem Biol. 2014 Sep 19;9(9):1997-2002. doi: 10.1021/cb500475y.

18.

Neuroinflammation: good, bad, or indifferent?

Kielian T.

J Neurochem. 2014 Jul;130(1):1-3. doi: 10.1111/jnc.12755. No abstract available.

19.

Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).

Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T.

PLoS One. 2014 Apr 15;9(4):e95023. doi: 10.1371/journal.pone.0095023.

20.

Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection.

Heim CE, Vidlak D, Scherr TD, Kozel JA, Holzapfel M, Muirhead DE, Kielian T.

J Immunol. 2014 Apr 15;192(8):3778-92. doi: 10.4049/jimmunol.1303408.

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