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Items: 1 to 20 of 85

1.

Recently evolved tumor suppressor transcript TP73-AS1 functions as sponge of human-specific miR-941.

Hu H, Liu JM, Hu Z, Jiang X, Yang X, Li J, Zhang Y, Yu H, Khaitovich P.

Mol Biol Evol. 2018 Feb 20. doi: 10.1093/molbev/msy022. [Epub ahead of print]

PMID:
29474580
2.

Predominant patterns of splicing evolution on human, chimpanzee and macaque evolutionary lineages.

Xiong J, Jiang X, Ditsiou A, Gao Y, Sun J, Lowenstein ED, Huang S, Khaitovich P.

Hum Mol Genet. 2018 Apr 15;27(8):1474-1485. doi: 10.1093/hmg/ddy058.

PMID:
29452398
3.

Conservation, evolution, and regulation of splicing during prefrontal cortex development in humans, chimpanzees, and macaques.

Mazin PV, Jiang X, Fu N, Han D, Guo M, Gelfand MS, Khaitovich P.

RNA. 2018 Apr;24(4):585-596. doi: 10.1261/rna.064931.117. Epub 2018 Jan 23.

PMID:
29363555
4.

Constrained vertebrate evolution by pleiotropic genes.

Hu H, Uesaka M, Guo S, Shimai K, Lu TM, Li F, Fujimoto S, Ishikawa M, Liu S, Sasagawa Y, Zhang G, Kuratani S, Yu JK, Kusakabe TG, Khaitovich P, Irie N; EXPANDE Consortium.

Nat Ecol Evol. 2017 Nov;1(11):1722-1730. doi: 10.1038/s41559-017-0318-0. Epub 2017 Sep 25.

PMID:
28963548
5.

Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity.

Dönertaş HM, İzgi H, Kamacıoğlu A, He Z, Khaitovich P, Somel M.

Sci Rep. 2017 Jul 19;7(1):5894. doi: 10.1038/s41598-017-05927-4.

6.

Comprehensive transcriptome analysis of neocortical layers in humans, chimpanzees and macaques.

He Z, Han D, Efimova O, Guijarro P, Yu Q, Oleksiak A, Jiang S, Anokhin K, Velichkovsky B, Grünewald S, Khaitovich P.

Nat Neurosci. 2017 Jun;20(6):886-895. doi: 10.1038/nn.4548. Epub 2017 Apr 17.

PMID:
28414332
7.

Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys.

Li Q, Bozek K, Xu C, Guo Y, Sun J, Pääbo S, Sherwood CC, Hof PR, Ely JJ, Li Y, Willmitzer L, Giavalisco P, Khaitovich P.

Mol Biol Evol. 2017 May 1;34(5):1155-1166. doi: 10.1093/molbev/msx065.

8.

Lipidome determinants of maximal lifespan in mammals.

Bozek K, Khrameeva EE, Reznick J, Omerbašić D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, Shi P, Pääbo S, Schroeder F, Willmitzer L, Giavalisco P, Khaitovich P.

Sci Rep. 2017 Jan 31;7(1):5. doi: 10.1038/s41598-017-00037-7.

9.

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism.

Liu X, Han D, Somel M, Jiang X, Hu H, Guijarro P, Zhang N, Mitchell A, Halene T, Ely JJ, Sherwood CC, Hof PR, Qiu Z, Pääbo S, Akbarian S, Khaitovich P.

PLoS Biol. 2016 Sep 29;14(9):e1002558. doi: 10.1371/journal.pbio.1002558. eCollection 2016 Sep.

10.

Fluoxetine Treatment Rescues Energy Metabolism Pathway Alterations in a Posttraumatic Stress Disorder Mouse Model.

Kao CY, He Z, Henes K, Asara JM, Webhofer C, Filiou MD, Khaitovich P, Wotjak CT, Turck CW.

Mol Neuropsychiatry. 2016 May;2(1):46-59. doi: 10.1159/000445377. Epub 2016 Apr 30.

11.

Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development.

Li Q, Guo S, Jiang X, Bryk J, Naumann R, Enard W, Tomita M, Sugimoto M, Khaitovich P, Pääbo S.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5358-63. doi: 10.1073/pnas.1519261113. Epub 2016 Apr 26.

12.

Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain.

Zhang B, Han D, Korostelev Y, Yan Z, Shao N, Khrameeva E, Velichkovsky BM, Chen YP, Gelfand MS, Khaitovich P.

Genome Biol Evol. 2016 Mar 23;8(3):840-50. doi: 10.1093/gbe/evw038.

13.

Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder.

Kao CY, He Z, Zannas AS, Hahn O, Kühne C, Reichel JM, Binder EB, Wotjak CT, Khaitovich P, Turck CW.

J Psychiatr Res. 2016 May;76:74-83. doi: 10.1016/j.jpsychires.2016.02.003. Epub 2016 Feb 8.

PMID:
26897419
14.

Evaluating intra- and inter-individual variation in the human placental transcriptome.

Hughes DA, Kircher M, He Z, Guo S, Fairbrother GL, Moreno CS, Khaitovich P, Stoneking M.

Genome Biol. 2015 Mar 19;16:54. doi: 10.1186/s13059-015-0627-z.

15.

Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging.

Wei YN, Hu HY, Xie GC, Fu N, Ning ZB, Zeng R, Khaitovich P.

Genome Biol. 2015 Feb 22;16:41. doi: 10.1186/s13059-015-0608-2.

16.

Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues.

Bozek K, Wei Y, Yan Z, Liu X, Xiong J, Sugimoto M, Tomita M, Pääbo S, Sherwood CC, Hof PR, Ely JJ, Li Y, Steinhauser D, Willmitzer L, Giavalisco P, Khaitovich P.

Neuron. 2015 Feb 18;85(4):695-702. doi: 10.1016/j.neuron.2015.01.003. Epub 2015 Feb 5.

17.

De novo identification and quantification of single amino-acid variants in human brain.

Su ZD, Sheng QH, Li QR, Chi H, Jiang X, Yan Z, Fu N, He SM, Khaitovich P, Wu JR, Zeng R.

J Mol Cell Biol. 2014 Oct;6(5):421-33. doi: 10.1093/jmcb/mju031. Epub 2014 Jul 9.

PMID:
25007923
18.

Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes.

Hu HY, He L, Khaitovich P.

BMC Genomics. 2014 Jun 10;15:457. doi: 10.1186/1471-2164-15-457.

19.

Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness.

Bozek K, Wei Y, Yan Z, Liu X, Xiong J, Sugimoto M, Tomita M, Pääbo S, Pieszek R, Sherwood CC, Hof PR, Ely JJ, Steinhauser D, Willmitzer L, Bangsbo J, Hansson O, Call J, Giavalisco P, Khaitovich P.

PLoS Biol. 2014 May 27;12(5):e1001871. doi: 10.1371/journal.pbio.1001871. eCollection 2014 May.

20.

Conserved expression of lincRNA during human and macaque prefrontal cortex development and maturation.

He Z, Bammann H, Han D, Xie G, Khaitovich P.

RNA. 2014 Jul;20(7):1103-11. doi: 10.1261/rna.043075.113. Epub 2014 May 20.

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