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Items: 1 to 20 of 37

1.

Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression.

Ghosh A, Abdelwahab SH, Reeber SL, Reidel B, Marklew AJ, Garrison AJ, Lee S, Dang H, Herring AH, Glish GL, Kesimer M, Tarran R.

Sci Rep. 2017 Apr 27;7:46239. doi: 10.1038/srep46239.

2.

Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways.

Abdullah LH, Evans JR, Wang TT, Ford AA, Makhov AM, Nguyen K, Coakley RD, Griffith JD, Davis CW, Ballard ST, Kesimer M.

JCI Insight. 2017 Mar 23;2(6):e89752. doi: 10.1172/jci.insight.89752.

3.

Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization.

Dickey BF, Fahy JV, Kesimer M, Boucher RC, Evans CM, Thornton D.

Ann Am Thorac Soc. 2016 Nov;13(11):2103-2104. No abstract available.

PMID:
27831803
4.

Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.

Cho JL, Ling MF, Adams DC, Faustino L, Islam SA, Afshar R, Griffith JW, Harris RS, Ng A, Radicioni G, Ford AA, Han AK, Xavier R, Kwok WW, Boucher R, Moon JJ, Hamilos DL, Kesimer M, Suter MJ, Medoff BD, Luster AD.

Sci Transl Med. 2016 Oct 5;8(359):359ra132.

5.

Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function.

Woodruff PG, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Lazarus SC, Martinez FJ, Paine R 3rd, Rennard S, Tashkin DP, Han MK; SPIROMICS Research Group.

N Engl J Med. 2016 May 12;374(19):1811-21. doi: 10.1056/NEJMoa1505971.

6.

The innate immune properties of airway mucosal surfaces are regulated by dynamic interactions between mucins and interacting proteins: the mucin interactome.

Radicioni G, Cao R, Carpenter J, Ford AA, Wang TT, Li Y, Kesimer M.

Mucosal Immunol. 2016 Nov;9(6):1442-1454. doi: 10.1038/mi.2016.27. Epub 2016 Apr 13.

7.

Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs.

Kesimer M, Cullen J, Cao R, Radicioni G, Mathews KG, Seiler G, Gookin JL.

PLoS One. 2015 Sep 28;10(9):e0138988. doi: 10.1371/journal.pone.0138988. eCollection 2015.

8.

The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis.

Anderson WH, Coakley RD, Button B, Henderson AG, Zeman KL, Alexis NE, Peden DB, Lazarowski ER, Davis CW, Bailey S, Fuller F, Almond M, Qaqish B, Bordonali E, Rubinstein M, Bennett WD, Kesimer M, Boucher RC.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):182-90. doi: 10.1164/rccm.201412-2230OC.

9.

Physical characterization and profiling of airway epithelial derived exosomes using light scattering.

Kesimer M, Gupta R.

Methods. 2015 Oct 1;87:59-63. doi: 10.1016/j.ymeth.2015.03.013. Epub 2015 Mar 27.

10.

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure.

Henderson AG, Ehre C, Button B, Abdullah LH, Cai LH, Leigh MW, DeMaria GC, Matsui H, Donaldson SH, Davis CW, Sheehan JK, Boucher RC, Kesimer M.

J Clin Invest. 2014 Jul;124(7):3047-60. doi: 10.1172/JCI73469. Epub 2014 Jun 2.

11.

Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures.

Hobbs CA, Blanchard MG, Alijevic O, Tan CD, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Henderson AG, Redinbo MR, Stutts MJ, Tarran R.

Am J Physiol Lung Cell Mol Physiol. 2013 Dec;305(12):L990-L1001. doi: 10.1152/ajplung.00103.2013. Epub 2013 Oct 11. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1;306(7):L708.

12.

Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS).

Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff PG, Rennard S; SPIROMICS Research Group.

Thorax. 2014 May;69(5):491-4. doi: 10.1136/thoraxjnl-2013-203897. Epub 2013 Sep 12.

13.

The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status.

Guo X, Kesimer M, Tolun G, Zheng X, Xu Q, Lu J, Sheehan JK, Griffith JD, Li X.

Sci Rep. 2012;2:640. doi: 10.1038/srep00640. Epub 2012 Sep 7.

14.

Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways.

Kesimer M, Ehre C, Burns KA, Davis CW, Sheehan JK, Pickles RJ.

Mucosal Immunol. 2013 Mar;6(2):379-92. doi: 10.1038/mi.2012.81. Epub 2012 Aug 29.

15.

A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia.

Button B, Cai LH, Ehre C, Kesimer M, Hill DB, Sheehan JK, Boucher RC, Rubinstein M.

Science. 2012 Aug 24;337(6097):937-41. doi: 10.1126/science.1223012.

16.

Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways.

Hobbs CA, Blanchard MG, Kellenberger S, Bencharit S, Cao R, Kesimer M, Walton WG, Redinbo MR, Stutts MJ, Tarran R.

FASEB J. 2012 Oct;26(10):4348-59. doi: 10.1096/fj.12-207431. Epub 2012 Jul 13. Retraction in: FASEB J. 2013 May;27(5):2081.

17.

Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients.

Gercel-Taylor C, Atay S, Tullis RH, Kesimer M, Taylor DD.

Anal Biochem. 2012 Sep 1;428(1):44-53. doi: 10.1016/j.ab.2012.06.004. Epub 2012 Jun 9.

PMID:
22691960
18.

Mapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study.

Cao R, Wang TT, DeMaria G, Sheehan JK, Kesimer M.

J Proteome Res. 2012 Aug 3;11(8):4013-23. doi: 10.1021/pr300058z. Epub 2012 Jun 28.

19.

Studying mucin secretion from human bronchial epithelial cell primary cultures.

Abdullah LH, Wolber C, Kesimer M, Sheehan JK, Davis CW.

Methods Mol Biol. 2012;842:259-77. doi: 10.1007/978-1-61779-513-8_16.

20.

Mass spectrometric analysis of mucin core proteins.

Kesimer M, Sheehan JK.

Methods Mol Biol. 2012;842:67-79. doi: 10.1007/978-1-61779-513-8_4.

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