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Items: 1 to 20 of 87

1.

Genome sequencing in a case of Niemann-Pick type C.

Dougherty M, Lazar J, Klein JC, Diaz K, Gobillot T, Grunblatt E, Hasle N, Lawrence D, Maurano M, Nelson M, Olson G, Srivatsan S, Shendure J, Keene CD, Bird T, Horwitz MS, Marshall DA.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001222.

2.

Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample.

Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth WT Jr, Woltjer RL, Kukull WA.

Alzheimers Dement. 2016 Nov 18. pii: S1552-5260(16)33057-6. doi: 10.1016/j.jalz.2016.09.015. [Epub ahead of print]

PMID:
27870939
3.

Primary Gliosarcoma of the Optic Nerve: A Unique Adult Optic Pathway Glioma.

Cimino PJ, Sychev YV, Gonzalez-Cuyar LF, Mudumbai RC, Keene CD.

Ophthal Plast Reconstr Surg. 2016 Oct 11. [Epub ahead of print]

PMID:
27792048
4.

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J.

Neuron. 2016 Oct 5;92(1):252-264. doi: 10.1016/j.neuron.2016.09.016. No abstract available.

PMID:
27710785
5.

Glucose levels during life and neuropathologic findings at autopsy among people never treated for diabetes.

Crane PK, Walker RL, Sonnen J, Gibbons LE, Melrose R, Hassenstab J, Keene CD, Postupna N, Montine TJ, Larson EB.

Neurobiol Aging. 2016 Aug 1;48:72-82. doi: 10.1016/j.neurobiolaging.2016.07.021. [Epub ahead of print]

PMID:
27644076
6.

Orbital Peripheral Nerve Sheath Tumors.

Sweeney AR, Gupta D, Keene CD, Cimino PJ, Chambers CB, Chang SH, Hanna E.

Surv Ophthalmol. 2016 Aug 25. pii: S0039-6257(16)30025-X. doi: 10.1016/j.survophthal.2016.08.002. [Epub ahead of print] Review.

PMID:
27570221
7.

Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease.

Beckelman BC, Day S, Zhou X, Donohue M, Gouras GK, Klann E, Keene CD, Ma T.

J Alzheimers Dis. 2016 Sep 6;54(2):669-78. doi: 10.3233/JAD-160036.

PMID:
27567813
8.

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.

Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Currey HN, Taylor LM, Wheeler JM, Oblak AL, Ghetti B, Montine TJ, Keene CD, Raskind MA, Bird TD, Kraemer BC.

Acta Neuropathol. 2016 Oct;132(4):545-61. doi: 10.1007/s00401-016-1600-y.

PMID:
27473149
9.

Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.

Crane PK, Gibbons LE, Dams-O'Connor K, Trittschuh E, Leverenz JB, Keene CD, Sonnen J, Montine TJ, Bennett DA, Leurgans S, Schneider JA, Larson EB.

JAMA Neurol. 2016 Sep 1;73(9):1062-9. doi: 10.1001/jamaneurol.2016.1948.

PMID:
27400367
10.

Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines.

Keene CD, Darvas M, Kraemer B, Liggitt D, Sigurdson C, Ladiges W.

Pathobiol Aging Age Relat Dis. 2016 Jun 16;6:32397. doi: 10.3402/pba.v6.32397.

11.

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J.

Neuron. 2016 May 18;90(4):724-39. doi: 10.1016/j.neuron.2016.05.003.

PMID:
27196974
12.

Mutational status of IDH1 in uveal melanoma.

Cimino PJ, Kung Y, Warrick JI, Chang SH, Keene CD.

Exp Mol Pathol. 2016 Jun;100(3):476-81. doi: 10.1016/j.yexmp.2016.05.002.

PMID:
27155448
13.

Unbiased Stereological Analysis of Reactive Astrogliosis to Estimate Age-Associated Cerebral White Matter Injury.

McNeal DW, Brandner DD, Gong X, Postupna NO, Montine TJ, Keene CD, Back SA.

J Neuropathol Exp Neurol. 2016 Jun;75(6):539-54. doi: 10.1093/jnen/nlw032.

PMID:
27142644
14.

Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4.

Melief EJ, Gibbs JT, Li X, Morgan RG, Keene CD, Montine TJ, Palmiter RD, Darvas M.

Neuroscience. 2016 Jun 2;324:399-406. doi: 10.1016/j.neuroscience.2016.03.037.

PMID:
27001174
15.

Unusually long duration and delayed penetrance in a family with FTD and mutation in MAPT (V337M).

Domoto-Reilly K, Davis MY, Keene CD, Bird TD.

Am J Med Genet B Neuropsychiatr Genet. 2016 Mar 16. doi: 10.1002/ajmg.b.32443. [Epub ahead of print]

PMID:
26990251
16.

Precision Medicine: Clarity for the Complexity of Dementia.

Cholerton B, Larson EB, Quinn JF, Zabetian CP, Mata IF, Keene CD, Flanagan M, Crane PK, Grabowski TJ, Montine KS, Montine TJ.

Am J Pathol. 2016 Mar;186(3):500-6. doi: 10.1016/j.ajpath.2015.12.001. Review.

PMID:
26724389
17.

The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy.

McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA; TBI/CTE group..

Acta Neuropathol. 2016 Jan;131(1):75-86. doi: 10.1007/s00401-015-1515-z.

18.

Importance of home study visit capacity in dementia studies.

Crane PK, Gibbons LE, McCurry SM, McCormick W, Bowen JD, Sonnen J, Keene CD, Grabowski T, Montine TJ, Larson EB.

Alzheimers Dement. 2016 Apr;12(4):419-26. doi: 10.1016/j.jalz.2015.10.007.

PMID:
26602628
19.

Impaired Eukaryotic Elongation Factor 1A Expression in Alzheimer's Disease.

Beckelman BC, Zhou X, Keene CD, Ma T.

Neurodegener Dis. 2016;16(1-2):39-43. doi: 10.1159/000438925.

PMID:
26551858
20.

The APOE Gene is Differentially Methylated in Alzheimer's Disease.

Foraker J, Millard SP, Leong L, Thomson Z, Chen S, Keene CD, Bekris LM, Yu CE.

J Alzheimers Dis. 2015;48(3):745-55. doi: 10.3233/JAD-143060.

PMID:
26402071
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