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Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.

Botkjaer KA, Kwok HF, Terp MG, Karatt-Vellatt A, Santamaria S, McCafferty J, Andreasen PA, Itoh Y, Ditzel HJ, Murphy G.

Oncotarget. 2016 Mar 29;7(13):16773-92. doi: 10.18632/oncotarget.7780.


A roadmap to generate renewable protein binders to the human proteome.

Colwill K; Renewable Protein Binder Working Group, Gräslund S.

Nat Methods. 2011 May 15;8(7):551-8. doi: 10.1038/nmeth.1607.


Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.

Pershad K, Pavlovic JD, Gräslund S, Nilsson P, Colwill K, Karatt-Vellatt A, Schofield DJ, Dyson MR, Pawson T, Kay BK, McCafferty J.

Protein Eng Des Sel. 2010 Apr;23(4):279-88. doi: 10.1093/protein/gzq003. Epub 2010 Feb 17.

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