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Items: 1 to 20 of 229


Proteoglycans remodeling in cancer: Underlying molecular mechanisms.

Theocharis AD, Karamanos NK.

Matrix Biol. 2017 Nov 8. pii: S0945-053X(17)30313-X. doi: 10.1016/j.matbio.2017.10.008. [Epub ahead of print] Review.


Insights into the key roles of epigenetics in matrix macromolecules-associated wound healing.

Piperigkou Z, Götte M, Theocharis AD, Karamanos NK.

Adv Drug Deliv Rev. 2017 Oct 24. pii: S0169-409X(17)30232-6. doi: 10.1016/j.addr.2017.10.008. [Epub ahead of print]


Extracellular matrix alterations in senescent cells and their significance in tissue homeostasis.

Mavrogonatou E, Pratsinis H, Papadopoulou A, Karamanos NK, Kletsas D.

Matrix Biol. 2017 Oct 21. pii: S0945-053X(17)30296-2. doi: 10.1016/j.matbio.2017.10.004. [Epub ahead of print] Review.


Estrogen receptor beta as epigenetic mediator of miR-10b and miR-145 in mammary cancer.

Piperigkou Z, Franchi M, Götte M, Karamanos NK.

Matrix Biol. 2017 Dec;64:94-111. doi: 10.1016/j.matbio.2017.08.002. Epub 2017 Aug 8.


IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.

Afratis NA, Bouris P, Skandalis SS, Multhaupt HA, Couchman JR, Theocharis AD, Karamanos NK.

Sci Rep. 2017 Jan 12;7:40138. doi: 10.1038/srep40138.


Matrix pathobiology-central roles for proteoglycans and heparanase in health and disease.

Karamanos NK.

FEBS J. 2017 Jan;284(1):7-9. doi: 10.1111/febs.13945.


Syndecans - key regulators of cell signaling and biological functions.

Afratis NA, Nikitovic D, Multhaupt HA, Theocharis AD, Couchman JR, Karamanos NK.

FEBS J. 2017 Jan;284(1):27-41. doi: 10.1111/febs.13940. Epub 2016 Nov 18. Review.


Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer.

Karousou E, Misra S, Ghatak S, Dobra K, Götte M, Vigetti D, Passi A, Karamanos NK, Skandalis SS.

Matrix Biol. 2017 May;59:3-22. doi: 10.1016/j.matbio.2016.10.001. Epub 2016 Oct 13. Review.


Data on the putative role of p53 in breast cancer cell adhesion: Technical information for adhesion assay.

Voudouri K, Nikitovic D, Berdiaki A, Tsiaoussis J, Kletsas D, Karamanos NK, Tzanakakis GN.

Data Brief. 2016 Sep 30;9:568-572. eCollection 2016 Dec.


Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.

Liakou E, Mavrogonatou E, Pratsinis H, Rizou S, Evangelou K, Panagiotou PN, Karamanos NK, Gorgoulis VG, Kletsas D.

Aging (Albany NY). 2016 Aug;8(8):1650-69. doi: 10.18632/aging.100989.


IGF-I/EGF and E2 signaling crosstalk through IGF-IR conduit point affects breast cancer cell adhesion.

Voudouri K, Nikitovic D, Berdiaki A, Kletsas D, Karamanos NK, Tzanakakis GN.

Matrix Biol. 2016 Dec;56:95-113. doi: 10.1016/j.matbio.2016.06.005. Epub 2016 Jun 25.


Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules.

Piperigkou Z, Bouris P, Onisto M, Franchi M, Kletsas D, Theocharis AD, Karamanos NK.

Matrix Biol. 2016 Dec;56:4-23. doi: 10.1016/j.matbio.2016.05.003. Epub 2016 May 11.


Synthesis and antiproliferative activity of two diastereomeric lignan amides serving as dimeric caffeic acid-l-DOPA hybrids.

Magoulas GE, Rigopoulos A, Piperigkou Z, Gialeli C, Karamanos NK, Takis PG, Troganis AN, Chrissanthopoulos A, Maroulis G, Papaioannou D.

Bioorg Chem. 2016 Jun;66:132-44. doi: 10.1016/j.bioorg.2016.04.003. Epub 2016 Apr 23.


Investigation on Toxicity and Teratogenicity in Rats of a Retinoid-Polyamine Conjugate with Potent Anti-Inflammatory Properties.

Petridis T, Giannakopoulou D, Stamatopoulou V, Grafanaki K, Kostopoulos CG, Papadaki H, Malavaki CJ, Karamanos NK, Douroumi S, Papachristou D, Magoulas GE, Papaioannou D, Drainas D.

Birth Defects Res B Dev Reprod Toxicol. 2016 Feb;107(1):32-44. doi: 10.1002/bdrb.21170. Epub 2016 Jan 13.


Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.

Korpetinou A, Papachristou DJ, Lampropoulou A, Bouris P, Labropoulou VT, Noulas A, Karamanos NK, Theocharis AD.

Biomed Res Int. 2015;2015:690721. doi: 10.1155/2015/690721. Epub 2015 Oct 25.


Extracellular matrix structure.

Theocharis AD, Skandalis SS, Gialeli C, Karamanos NK.

Adv Drug Deliv Rev. 2016 Feb 1;97:4-27. doi: 10.1016/j.addr.2015.11.001. Epub 2015 Nov 10. Review.


Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma.

Heidari-Hamedani G, Vivès RR, Seffouh A, Afratis NA, Oosterhof A, van Kuppevelt TH, Karamanos NK, Metintas M, Hjerpe A, Dobra K, Szatmári T.

Cell Signal. 2015 Oct;27(10):2054-67. doi: 10.1016/j.cellsig.2015.07.017. Epub 2015 Jul 23. Erratum in: Cell Signal. 2015 Dec;27(12):2599-601.


Increased β-glucuronidase activity in bronchoalveolar lavage fluid of children with bacterial lung infection: A case-control study.

Panagiotopoulou EC, Fouzas S, Douros K, Triantaphyllidou IE, Malavaki C, Priftis KN, Karamanos NK, Anthracopoulos MB.

Respirology. 2015 Nov;20(8):1248-54. doi: 10.1111/resp.12596. Epub 2015 Jul 14.


Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.

Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, Karamanos NK.

Biochim Biophys Acta. 2015 Apr;1855(2):276-300. doi: 10.1016/j.bbcan.2015.03.006. Epub 2015 Mar 28. Review.


Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Bouris P, Skandalis SS, Piperigkou Z, Afratis N, Karamanou K, Aletras AJ, Moustakas A, Theocharis AD, Karamanos NK.

Matrix Biol. 2015 Apr;43:42-60. doi: 10.1016/j.matbio.2015.02.008. Epub 2015 Feb 27.

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