Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 49


Progranulin Stimulates the In Vitro Maturation of Pro-Cathepsin D at Acidic pH.

Butler VJ, Cortopassi WA, Argouarch AR, Ivry SL, Craik CS, Jacobson MP, Kao AW.

J Mol Biol. 2019 Jan 25. pii: S0022-2836(18)31059-3. doi: 10.1016/j.jmb.2019.01.027. [Epub ahead of print]


Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.

Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, Ashrafi K, Mandelkow EM, Encalada SE, Kao AW.

Hum Mol Genet. 2018 Dec 26. doi: 10.1093/hmg/ddy442. [Epub ahead of print]


Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress.

Yuan SH, Hiramatsu N, Liu Q, Sun XV, Lenh D, Chan P, Chiang K, Koo EH, Kao AW, Litvan I, Lin JH.

Hum Mol Genet. 2018 Nov 15;27(22):3951-3963. doi: 10.1093/hmg/ddy297.


The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response.

Hsu TY, Butler VJ, Kao AW.

Methods Mol Biol. 2018;1806:193-206. doi: 10.1007/978-1-4939-8559-3_14.


Clinicopathological correlations in behavioural variant frontotemporal dementia.

Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Nana AL, Vargas JNS, Hwang JL, Ossenkoppele R, Brown AB, Huang EJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW.

Brain. 2017 Dec 1;140(12):3329-3345. doi: 10.1093/brain/awx254.


Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia.

Olney NT, Alquezar C, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, De May M, Seeley WW, Coppola G, Miller BL, Kao AW.

Acta Neuropathol. 2017 Nov;134(5):813-816. doi: 10.1007/s00401-017-1764-0. Epub 2017 Aug 21. No abstract available.


Progranulin, lysosomal regulation and neurodegenerative disease.

Kao AW, McKay A, Singh PP, Brunet A, Huang EJ.

Nat Rev Neurosci. 2017 Jun;18(6):325-333. doi: 10.1038/nrn.2017.36. Epub 2017 Apr 24. Review.


MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes.

Bettcher BM, Fitch R, Wynn MJ, Lalli MA, Elofson J, Jastrzab L, Mitic L, Miller ZA, Rabinovici GD, Miller BL, Kao AW, Kosik KS, Kramer JH.

Alzheimers Dement (Amst). 2016 Jun 22;3:91-7. doi: 10.1016/j.dadm.2016.05.004. eCollection 2016.


Inhibitory Effects of AVEMAR on Proliferation and Metastasis of Oral Cancer Cells.

Yang MD, Chang WS, Tsai CW, Wang MF, Chan YC, Chan KC, Lu MC, Kao AW, Hsu CM, Bau DT.

Nutr Cancer. 2016;68(3):473-80. doi: 10.1080/01635581.2016.1153668. Epub 2016 Mar 23.


Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease.

Lalli MA, Bettcher BM, Arcila ML, Garcia G, Guzman C, Madrigal L, Ramirez L, Acosta-Uribe J, Baena A, Wojta KJ, Coppola G, Fitch R, de Both MD, Huentelman MJ, Reiman EM, Brunkow ME, Glusman G, Roach JC, Kao AW, Lopera F, Kosik KS.

Mol Psychiatry. 2015 Nov;20(11):1294-300. doi: 10.1038/mp.2015.131. Epub 2015 Sep 1.


The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.

Salazar DA, Butler VJ, Argouarch AR, Hsu TY, Mason A, Nakamura A, McCurdy H, Cox D, Ng R, Pan G, Seeley WW, Miller BL, Kao AW.

J Neurosci. 2015 Jun 24;35(25):9315-28. doi: 10.1523/JNEUROSCI.4808-14.2015.


SLCO3A1, A novel crohn's disease-associated gene, regulates nf-κB activity and associates with intestinal perforation.

Wei SC, Tan YY, Weng MT, Lai LC, Hsiao JH, Chuang EY, Shun CT, Wu DC, Kao AW, Chuang CS, Ni YH, Shieh MJ, Tung CC, Chen Y, Wang CY, Xavier RJ, Podolsky DK, Wong JM.

PLoS One. 2014 Jun 19;9(6):e100515. doi: 10.1371/journal.pone.0100515. eCollection 2014.


Increasing incidence and lifetime risk of inflammatory bowel disease in Taiwan: a nationwide study in a low-endemic area 1998-2010.

Chuang CH, Lin SH, Chen CY, Sheu BS, Kao AW, Wang JD.

Inflamm Bowel Dis. 2013 Dec;19(13):2815-9. doi: 10.1097/01.MIB.0000435436.99612.27.


A shift to organismal stress resistance in programmed cell death mutants.

Judy ME, Nakamura A, Huang A, Grant H, McCurdy H, Weiberth KF, Gao F, Coppola G, Kenyon C, Kao AW.

PLoS Genet. 2013;9(9):e1003714. doi: 10.1371/journal.pgen.1003714. Epub 2013 Sep 19.


Genome sequence of a novel human pathogen, Aeromonas aquariorum.

Wu CJ, Wang HC, Chen CS, Shu HY, Kao AW, Chen PL, Ko WC.

J Bacteriol. 2012 Aug;194(15):4114-5. doi: 10.1128/JB.00621-12.


Comparison of presentation and impact on quality of life of gastroesophageal reflux disease between young and old adults in a Chinese population.

Lee SW, Chang CM, Chang CS, Kao AW, Chou MC.

World J Gastroenterol. 2011 Nov 7;17(41):4614-8. doi: 10.3748/wjg.v17.i41.4614.


A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.

Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV Jr, Kenyon C.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4441-6. doi: 10.1073/pnas.1100650108. Epub 2011 Feb 28.


Cognitive and neuropsychiatric profile of the synucleinopathies: Parkinson disease, dementia with Lewy bodies, and multiple system atrophy.

Kao AW, Racine CA, Quitania LC, Kramer JH, Christine CW, Miller BL.

Alzheimer Dis Assoc Disord. 2009 Oct-Dec;23(4):365-70. doi: 10.1097/WAD.0b013e3181b5065d.


Airway infection predisposes to peristomal infection after percutaneous endoscopic gastrostomy with high concordance between sputum and wound isolates.

Chuang CH, Hung KH, Chen JR, Chen CY, Kao AW, Chang WL, Wu JJ, Sheu BS.

J Gastrointest Surg. 2010 Jan;14(1):45-51. doi: 10.1007/s11605-009-1058-5. Epub 2009 Oct 9.


Gender difference of circulating ghrelin and leptin concentrations in chronic Helicobacter pylori infection.

Chuang CH, Sheu BS, Yang HB, Lee SC, Kao AW, Cheng HC, Chang WL, Yao WJ.

Helicobacter. 2009 Feb;14(1):54-60. doi: 10.1111/j.1523-5378.2009.00653.x.


Supplemental Content

Support Center