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Items: 1 to 20 of 317

1.

The metabolism and drug-drug interaction potential of the selective prostacyclin receptor agonist selexipag.

Gnerre C, Segrestaa J, Seeland S, Äänismaa P, Pfeifer T, Delahaye S, de Kanter R, Ichikawa T, Yamada T, Treiber A.

Xenobiotica. 2017 Aug 30:1-16. doi: 10.1080/00498254.2017.1357088. [Epub ahead of print]

PMID:
28737453
2.

The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468.

Treiber A, de Kanter R, Roch C, Gatfield J, Boss C, von Raumer M, Schindelholz B, Muehlan C, van Gerven J, Jenck F.

J Pharmacol Exp Ther. 2017 Sep;362(3):489-503. doi: 10.1124/jpet.117.241596. Epub 2017 Jun 29.

PMID:
28663311
3.

Letter to the Editor, Physiologically based pharmacokinetic predictions of intestinal BCRP-mediated effect of telmisartan on the pharmacokinetics of rosuvastatin in humans.

de Kanter R, Kohl C.

Biopharm Drug Dispos. 2017 Oct;38(7):443-444. doi: 10.1002/bdd.2079. Epub 2017 Jun 28. No abstract available.

PMID:
28656708
4.

Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.

Kannankeril PJ, Moore JP, Cerrone M, Priori SG, Kertesz NJ, Ro PS, Batra AS, Kaufman ES, Fairbrother DL, Saarel EV, Etheridge SP, Kanter RJ, Carboni MP, Dzurik MV, Fountain D, Chen H, Ely EW, Roden DM, Knollmann BC.

JAMA Cardiol. 2017 Jul 1;2(7):759-766. doi: 10.1001/jamacardio.2017.1320.

PMID:
28492868
5.

Arrhythmias Following the Mustard and Senning Operations for Dextro-Transposition of the Great Arteries: Clinical Aspects and Catheter Ablation.

Baysa SJ, Olen M, Kanter RJ.

Card Electrophysiol Clin. 2017 Jun;9(2):255-271. doi: 10.1016/j.ccep.2017.02.008. Epub 2017 Mar 22. Review.

PMID:
28457240
6.

Correction to Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.

Siegrist R, Pozzi D, Jacob G, Torrisi C, Colas K, Braibant B, Mawet J, Pfeifer T, de Kanter R, Roch C, Kessler M, Moon R, Corminboeuf O, Bezençon O.

J Med Chem. 2017 Mar 9;60(5):2163. doi: 10.1021/acs.jmedchem.7b00219. Epub 2017 Feb 24. No abstract available.

PMID:
28234473
7.

The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: findings from an international multicentre registry.

Roston TM, Yuchi Z, Kannankeril PJ, Hathaway J, Vinocur JM, Etheridge SP, Potts JE, Maginot KR, Salerno JC, Cohen MI, Hamilton RM, Pflaumer A, Mohammed S, Kimlicka L, Kanter RJ, LaPage MJ, Collins KK, Gebauer RA, Temple JD, Batra AS, Erickson C, Miszczak-Knecht M, Kubuš P, Bar-Cohen Y, Kantoch M, Thomas VC, Hessling G, Anderson C, Young ML, Choi SHJ, Cabrera Ortega M, Lau YR, Johnsrude CL, Fournier A, Van Petegem F, Sanatani S.

Europace. 2017 Jan 31. doi: 10.1093/europace/euw389. [Epub ahead of print]

PMID:
28158428
8.

Screening the apparently healthy athlete for risk: a paradigm in transition.

Kurtz JD, Kanter RJ, Olen M, Rossi AF.

Cardiol Young. 2017 Jan;27(S1):S89-S93. doi: 10.1017/S1047951116002298. Review.

PMID:
28084964
9.

Sudden cardiac arrest in patients following surgery for CHD.

Kanter RJ.

Cardiol Young. 2017 Jan;27(S1):S68-S74. doi: 10.1017/S1047951116002262. Review.

PMID:
28084952
10.

Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.

Siegrist R, Pozzi D, Jacob G, Torrisi C, Colas K, Braibant B, Mawet J, Pfeifer T, de Kanter R, Roch C, Kessler M, Corminboeuf O, Bezençon O.

J Med Chem. 2016 Dec 8;59(23):10661-10675. Epub 2016 Nov 23.

PMID:
27933950
11.

A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome.

Limpitikul WB, Dick IE, Tester DJ, Boczek NJ, Limphong P, Yang W, Choi MH, Babich J, DiSilvestre D, Kanter RJ, Tomaselli GF, Ackerman MJ, Yue DT.

Circ Res. 2017 Jan 6;120(1):39-48. doi: 10.1161/CIRCRESAHA.116.309283. Epub 2016 Oct 20.

PMID:
27765793
12.

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

Le Bihan A, de Kanter R, Angulo-Barturen I, Binkert C, Boss C, Brun R, Brunner R, Buchmann S, Burrows J, Dechering KJ, Delves M, Ewerling S, Ferrer S, Fischli C, Gamo-Benito FJ, Gnädig NF, Heidmann B, Jiménez-Díaz MB, Leroy D, Martínez MS, Meyer S, Moehrle JJ, Ng CL, Noviyanti R, Ruecker A, Sanz LM, Sauerwein RW, Scheurer C, Schleiferboeck S, Sinden R, Snyder C, Straimer J, Wirjanata G, Marfurt J, Price RN, Weller T, Fischli W, Fidock DA, Clozel M, Wittlin S.

PLoS Med. 2016 Oct 4;13(10):e1002138. doi: 10.1371/journal.pmed.1002138. eCollection 2016 Oct.

13.

Frequent Activation Delay-Induced Mechanical Dyssynchrony and Dysfunction in the Systemic Right Ventricle.

Forsha D, Risum N, Smith PB, Kanter RJ, Samad Z, Barker P, Kisslo J.

J Am Soc Echocardiogr. 2016 Nov;29(11):1074-1083. doi: 10.1016/j.echo.2016.08.002. Epub 2016 Sep 10.

PMID:
27624591
14.

Defibrillation Testing Strategies of Pediatric and Adult Congenital Electrophysiologists during ICD Implantation.

Baysa SJ, Olen M, Kanter RJ, Fishberger SB.

Pacing Clin Electrophysiol. 2016 Aug;39(8):843-7. doi: 10.1111/pace.12896. Epub 2016 Jun 27.

PMID:
27226114
15.

Tackling NCD in LMIC: Achievements and Lessons Learned From the NHLBI-UnitedHealth Global Health Centers of Excellence Program.

Engelgau MM, Sampson UK, Rabadan-Diehl C, Smith R, Miranda J, Bloomfield GS, Belis D, Narayan KM; National Health, Lung, and Blood Institute–UnitedHealth Global Health Centers of Excellence Collaborators.

Glob Heart. 2016 Mar;11(1):5-15. doi: 10.1016/j.gheart.2015.12.016. Review.

16.

Pediatric Triage in a Severe Pandemic: Maximizing Survival by Establishing Triage Thresholds.

Gall C, Wetzel R, Kolker A, Kanter RK, Toltzis P.

Crit Care Med. 2016 Sep;44(9):1762-8. doi: 10.1097/CCM.0000000000001759.

PMID:
27071069
17.

Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups.

Lescop C, Müller C, Mathys B, Birker M, de Kanter R, Kohl C, Hess P, Nayler O, Rey M, Sieber P, Steiner B, Weller T, Bolli MH.

Eur J Med Chem. 2016 Jun 30;116:222-238. doi: 10.1016/j.ejmech.2016.03.048. Epub 2016 Mar 23.

PMID:
27061986
18.

Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWG.

Brian W, Tremaine LM, Arefayene M, de Kanter R, Evers R, Guo Y, Kalabus J, Lin W, Loi CM, Xiao G.

Pharmacogenomics. 2016 Apr;17(6):615-31. doi: 10.2217/pgs.16.9. Epub 2016 Apr 5. Review.

PMID:
27045656
19.

Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.

Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B.

Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12.

PMID:
27027817
20.

[Dissertations 25 years after date 45. Prevalence and etiology of craniomandibular dysfunction in the Netherlands].

de Kanter RJ.

Ned Tijdschr Tandheelkd. 2016 Mar;123(3):138-44. doi: 10.5177/ntvt.2016.03.15218. Review. Dutch.

PMID:
26973986

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