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Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified Clostridium botulinum Strain.

Pellett S, Tepp WH, Bradshaw M, Kalb SR, Dykes JK, Lin G, Nawrocki EM, Pier CL, Barr JR, Maslanka SE, Johnson EA.

mSphere. 2016 Feb 24;1(1). pii: e00100-15. doi: 10.1128/mSphere.00100-15.


Improved Sensitivity for the Qualitative and Quantitative Analysis of Active Ricin by MALDI-TOF Mass Spectrometry.

Wang D, Baudys J, Barr JR, Kalb SR.

Anal Chem. 2016 Jul 5;88(13):6867-72. doi: 10.1021/acs.analchem.6b01486.


Recommended Mass Spectrometry-Based Strategies to Identify Ricin-Containing Samples.

Kalb SR, Schieltz DM, Becher F, Astot C, Fredriksson SÅ, Barr JR.

Toxins (Basel). 2015 Nov 25;7(12):4881-94. doi: 10.3390/toxins7124854.


Detection of the HA-33 protein in botulinum neurotoxin type G complex by mass spectrometry.

Kalb SR, Baudys J, Barr JR.

BMC Microbiol. 2015 Oct 23;15:227. doi: 10.1186/s12866-015-0567-5.


Mass Spectrometric Detection of Bacterial Protein Toxins and Their Enzymatic Activity.

Kalb SR, Boyer AE, Barr JR.

Toxins (Basel). 2015 Aug 31;7(9):3497-511. doi: 10.3390/toxins7093497. Review.


A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin.

Maslanka SE, Lúquez C, Dykes JK, Tepp WH, Pier CL, Pellett S, Raphael BH, Kalb SR, Barr JR, Rao A, Johnson EA.

J Infect Dis. 2016 Feb 1;213(3):379-85. doi: 10.1093/infdis/jiv327.


Recommended mass spectrometry-based strategies to identify botulinum neurotoxin-containing samples.

Kalb SR, Baudys J, Wang D, Barr JR.

Toxins (Basel). 2015 May 19;7(5):1765-78. doi: 10.3390/toxins7051765.


Enhanced detection of type C botulinum neurotoxin by the Endopep-MS assay through optimization of peptide substrates.

Wang D, Krilich J, Baudys J, Barr JR, Kalb SR.

Bioorg Med Chem. 2015 Jul 1;23(13):3667-73. doi: 10.1016/j.bmc.2015.04.012.


Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F/A).

Kalb SR, Baudys J, Raphael BH, Dykes JK, Lúquez C, Maslanka SE, Barr JR.

Anal Chem. 2015 Apr 7;87(7):3911-7. doi: 10.1021/ac504716v.


Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.

Kull S, Schulz KM, Weisemann J, Kirchner S, Schreiber T, Bollenbach A, Dabrowski PW, Nitsche A, Kalb SR, Dorner MB, Barr JR, Rummel A, Dorner BG.

PLoS One. 2015 Feb 6;10(2):e0116381. doi: 10.1371/journal.pone.0116381.


Detection of Botulinum Toxins A, B, E, and F in Foods by Endopep-MS.

Kalb SR, Krilich JC, Dykes JK, Lúquez C, Maslanka SE, Barr JR.

J Agric Food Chem. 2015 Jan 22.


A two-stage multiplex method for quantitative analysis of botulinum neurotoxins type A, B, E, and F by MALDI-TOF mass spectrometry.

Wang D, Baudys J, Krilich J, Smith TJ, Barr JR, Kalb SR.

Anal Chem. 2014 Nov 4;86(21):10847-54. doi: 10.1021/ac502948v.


Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay.

Wang D, Krilich J, Baudys J, Barr JR, Kalb SR.

Anal Biochem. 2015 Jan 1;468:15-21. doi: 10.1016/j.ab.2014.08.026.


Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum.

Björnstad K, Tevell Åberg A, Kalb SR, Wang D, Barr JR, Bondesson U, Hedeland M.

Anal Bioanal Chem. 2014 Nov;406(28):7149-61. doi: 10.1007/s00216-014-8170-4.


Clostridium botulinum strains producing BoNT/F4 or BoNT/F5.

Raphael BH, Bradshaw M, Kalb SR, Joseph LA, Lúquez C, Barr JR, Johnson EA, Maslanka SE.

Appl Environ Microbiol. 2014 May;80(10):3250-7. doi: 10.1128/AEM.00284-14.


Three enzymatically active neurotoxins of Clostridium botulinum strain Af84: BoNT/A2, /F4, and /F5.

Kalb SR, Baudys J, Smith TJ, Smith LA, Barr JR.

Anal Chem. 2014 Apr 1;86(7):3254-62. doi: 10.1021/ac5001509.


Comparison of the catalytic properties of the botulinum neurotoxin subtypes A1 and A5.

Wang D, Krilich J, Pellett S, Baudys J, Tepp WH, Barr JR, Johnson EA, Kalb SR.

Biochim Biophys Acta. 2013 Dec;1834(12):2722-8. doi: 10.1016/j.bbapap.2013.09.007.


Recovery and detection of botulinum neurotoxins from a nonporous surface.

Lautenschlager M, Maslanka SE, Paul PA, Kalb SR, Barr JR, Raphael BH.

J Microbiol Methods. 2013 Mar;92(3):278-80. doi: 10.1016/j.mimet.2012.12.019.


Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype.

Raphael BH, Lautenschlager M, Kalb SR, de Jong LI, Frace M, Lúquez C, Barr JR, Fernández RA, Maslanka SE.

BMC Microbiol. 2012 Oct 31;12:245. doi: 10.1186/1471-2180-12-245.

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