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Items: 1 to 20 of 80

1.

MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion.

Ast V, Kordaß T, Oswald M, Kolte A, Eisel D, Osen W, Eichmüller SB, Berndt A, König R.

Oncotarget. 2018 Oct 30;9(85):35559-35580. doi: 10.18632/oncotarget.26263. eCollection 2018 Oct 30.

2.

Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2:ERG fusion type prostate cancers.

Minner S, Lutz J, Hube-Magg C, Kluth M, Simon R, Höflmayer D, Burandt E, Tsourlakis MC, Sauter G, Büscheck F, Wilczak W, Steurer S, Schlomm T, Huland H, Graefen M, Haese A, Heinzer H, Jacobsen F, Hinsch A, Poos A, Oswald M, Rippe K, König R, Schroeder C.

Prostate. 2018 Nov 14. doi: 10.1002/pros.23736. [Epub ahead of print]

PMID:
30430607
3.

Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia.

Kresinsky A, Bauer R, Schnöder TM, Berg T, Meyer D, Ast V, König R, Serve H, Heidel FH, Böhmer FD, Müller JP.

Haematologica. 2018 Nov;103(11):e505-e509. doi: 10.3324/haematol.2017.185306. Epub 2018 Jun 7. No abstract available.

4.

Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells.

Ansari SS, Sharma AK, Zepp M, Ivanova E, Bergmann F, König R, Berger MR.

Oncotarget. 2017 Dec 20;9(5):5797-5810. doi: 10.18632/oncotarget.23537. eCollection 2018 Jan 19.

5.

Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells.

Ansari SS, Sharma AK, Soni H, Ali DM, Tews B, König R, Eibl H, Berger MR.

Cell Death Dis. 2018 Feb 20;9(3):296. doi: 10.1038/s41419-018-0342-2.

6.

Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.

Nat Commun. 2018 Jan 30;9(1):327. doi: 10.1038/s41467-017-02395-2.

7.

Combination of Classifiers Identifies Fungal-Specific Activation of Lysosome Genes in Human Monocytes.

Leonor Fernandes Saraiva JP, Zubiria-Barrera C, Klassert TE, Lautenbach MJ, Blaess M, Claus RA, Slevogt H, König R.

Front Microbiol. 2017 Nov 29;8:2366. doi: 10.3389/fmicb.2017.02366. eCollection 2017.

8.

Streptococcus pneumoniae From Patients With Hemolytic Uremic Syndrome Binds Human Plasminogen via the Surface Protein PspC and Uses Plasmin to Damage Human Endothelial Cells.

Meinel C, Spartà G, Dahse HM, Hörhold F, König R, Westermann M, Coldewey SM, Cseresnyés Z, Figge MT, Hammerschmidt S, Skerka C, Zipfel PF.

J Infect Dis. 2018 Jan 17;217(3):358-370. doi: 10.1093/infdis/jix305.

PMID:
28968817
9.

Fungal biomarker discovery by integration of classifiers.

Saraiva JP, Oswald M, Biering A, Röll D, Assmann C, Klassert T, Blaess M, Czakai K, Claus R, Löffler J, Slevogt H, König R.

BMC Genomics. 2017 Aug 10;18(1):601. doi: 10.1186/s12864-017-4006-x.

10.

Role of the ESCRT Complexes in Telomere Biology.

Dieckmann AK, Babin V, Harari Y, Eils R, König R, Luke B, Kupiec M.

MBio. 2016 Nov 8;7(6). pii: e01793-16. doi: 10.1128/mBio.01793-16.

11.

The Use of Tools, Modelling Methods, Data Types, and Endpoints in Systems Medicine: A Survey on Projects of the German e:Med-Programme.

Gietzelt M, Höfer T, Knaup-Gregori P, König R, Löpprich M, Poos A, Ganzinger M.

Stud Health Technol Inform. 2016;228:670-4.

PMID:
27577469
12.

Copy Number Alterations in Enzyme-Coding and Cancer-Causing Genes Reprogram Tumor Metabolism.

Sharma AK, Eils R, König R.

Cancer Res. 2016 Jul 15;76(14):4058-67. doi: 10.1158/0008-5472.CAN-15-2350. Epub 2016 May 23.

13.

SOX5 is involved in balanced MITF regulation in human melanoma cells.

Kordaß T, Weber CE, Oswald M, Ast V, Bernhardt M, Novak D, Utikal J, Eichmüller SB, König R.

BMC Med Genomics. 2016 Feb 29;9:10. doi: 10.1186/s12920-016-0170-0.

14.

Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast.

Poos AM, Maicher A, Dieckmann AK, Oswald M, Eils R, Kupiec M, Luke B, König R.

Nucleic Acids Res. 2016 Jun 2;44(10):e93. doi: 10.1093/nar/gkw111. Epub 2016 Feb 22.

15.

Femoral facial syndrome associated with a de novo complex chromosome 2q37 rearrangement.

Spielmann M, Marx S, Barbi G, Flöttmann R, Kehrer-Sawatzki H, König R, Horn D, Mundlos S, Nader S, Borck G.

Am J Med Genet A. 2016 May;170A(5):1202-7. doi: 10.1002/ajmg.a.37560. Epub 2016 Jan 29.

PMID:
26822876
16.

Causes of upregulation of glycolysis in lymphocytes upon stimulation. A comparison with other cell types.

Stark H, Fichtner M, König R, Lorkowski S, Schuster S.

Biochimie. 2015 Nov;118:185-94. doi: 10.1016/j.biochi.2015.09.017. Epub 2015 Sep 14. Review.

PMID:
26382968
17.

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction.

Weaver KN, Watt KE, Hufnagel RB, Navajas Acedo J, Linscott LL, Sund KL, Bender PL, König R, Lourenco CM, Hehr U, Hopkin RJ, Lohmann DR, Trainor PA, Wieczorek D, Saal HM.

Am J Hum Genet. 2015 May 7;96(5):765-74. doi: 10.1016/j.ajhg.2015.03.011. Epub 2015 Apr 23.

18.

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer.

Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, Breunig C, Münstermann E, König R, Keklikoglou I, Wiemann S.

Mol Oncol. 2015 Jun;9(6):1106-19. doi: 10.1016/j.molonc.2015.01.008. Epub 2015 Feb 10.

19.

A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes.

Khandelwal N, Breinig M, Speck T, Michels T, Kreutzer C, Sorrentino A, Sharma AK, Umansky L, Conrad H, Poschke I, Offringa R, König R, Bernhard H, Machlenkin A, Boutros M, Beckhove P.

EMBO Mol Med. 2015 Apr;7(4):450-63. doi: 10.15252/emmm.201404414.

20.

Large-scale tracking and classification for automatic analysis of cell migration and proliferation, and experimental optimization of high-throughput screens of neuroblastoma cells.

Harder N, Batra R, Diessl N, Gogolin S, Eils R, Westermann F, König R, Rohr K.

Cytometry A. 2015 Jun;87(6):524-40. doi: 10.1002/cyto.a.22632. Epub 2015 Jan 28.

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