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Items: 1 to 20 of 237


Fine Needle Aspiration of Thyroid Nodules Using the Bethesda System for Reporting Thyroid Cytopathology: An Institutional Experience in a Rural Setting.

Guo A, Kaminoh Y, Forward T, Schwartz FL, Jenkinson S.

Int J Endocrinol. 2017;2017:9601735. doi: 10.1155/2017/9601735.


Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins.

Jenkinson SP, Grandgirard D, Heidemann M, Tscherter A, Avondet MA, Leib SL.

Front Pharmacol. 2017 Feb 23;8:73. doi: 10.3389/fphar.2017.00073.


Synthesis and Biological Evaluation of Amidinourea and Triazine Congeners as Inhibitors of MDA-MB-231 Human Breast Cancer Cell Proliferation.

Bass R, Jenkinson S, Wright J, Smulders-Srinivasan T, Marshall JC, Castagnolo D.

ChemMedChem. 2017 Feb 20;12(4):288-291. doi: 10.1002/cmdc.201600580.


Identification of novel peptide motifs in the serpin maspin that affect vascular smooth muscle cell function.

Jenkinson SE, Brown LJ, Ombor J, Milburn JA, Smulders-Srinivasan T, Veuger S, Edwards DR, Bass R.

Biochim Biophys Acta. 2017 Feb;1864(2):336-344. doi: 10.1016/j.bbamcr.2016.11.019.


L-type calcium channel antagonism - Translation from in vitro to in vivo.

Fermini B, Ramirez DS, Sun S, Bassyouni A, Hemkens M, Wisialowski T, Jenkinson S.

J Pharmacol Toxicol Methods. 2017 Mar - Apr;84:86-92. doi: 10.1016/j.vascn.2016.11.002.


Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter.

Kelly CL, Liu Z, Yoshihara A, Jenkinson SF, Wormald MR, Otero J, Estévez A, Kato A, Marqvorsen MH, Fleet GW, Estévez RJ, Izumori K, Heap JT.

ACS Synth Biol. 2016 Oct 21;5(10):1136-1145.


Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids.

Glawar AF, Martínez RF, Ayers BJ, Hollas MA, Ngo N, Nakagawa S, Kato A, Butters TD, Fleet GW, Jenkinson SF.

Org Biomol Chem. 2016 Nov 8;14(44):10371-10385.


Triacetonide of Glucoheptonic Acid in the Scalable Syntheses of d-Gulose, 6-Deoxy-d-gulose, l-Glucose, 6-Deoxy-l-glucose, and Related Sugars.

Liu Z, Yoshihara A, Jenkinson SF, Wormald MR, Estévez RJ, Fleet GW, Izumori K.

Org Lett. 2016 Aug 19;18(16):4112-5. doi: 10.1021/acs.orglett.6b02041.


6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology.

Liu Z, Yoshihara A, Kelly C, Heap JT, Marqvorsen MH, Jenkinson SF, Wormald MR, Otero JM, Estévez A, Kato A, Fleet GW, Estévez RJ, Izumori K.

Chemistry. 2016 Aug 22;22(35):12557-65. doi: 10.1002/chem.201602482.


Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.

Davoren JE, Lee CW, Garnsey M, Brodney MA, Cordes J, Dlugolenski K, Edgerton JR, Harris AR, Helal CJ, Jenkinson S, Kauffman GW, Kenakin TP, Lazzaro JT, Lotarski SM, Mao Y, Nason DM, Northcott C, Nottebaum L, O'Neil SV, Pettersen B, Popiolek M, Reinhart V, Salomon-Ferrer R, Steyn SJ, Webb D, Zhang L, Grimwood S.

J Med Chem. 2016 Jul 14;59(13):6313-28. doi: 10.1021/acs.jmedchem.6b00544.


Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test.

Weisemann J, Krez N, Fiebig U, Worbs S, Skiba M, Endermann T, Dorner MB, Bergström T, Muñoz A, Zegers I, Müller C, Jenkinson SP, Avondet MA, Delbrassinne L, Denayer S, Zeleny R, Schimmel H, Åstot C, Dorner BG, Rummel A.

Toxins (Basel). 2015 Nov 26;7(12):5035-54. doi: 10.3390/toxins7124861.


Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial.

Jenkinson S, Kirkwood AA, Goulden N, Vora A, Linch DC, Gale RE.

Leukemia. 2016 Jan;30(1):39-47. doi: 10.1038/leu.2015.206.


Phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of phenolic acids on vascular smooth muscle cells in vitro.

Keane KM, Bell PG, Lodge JK, Constantinou CL, Jenkinson SE, Bass R, Howatson G.

Eur J Nutr. 2016 Jun;55(4):1695-705. doi: 10.1007/s00394-015-0988-9.


Simpson's Paradox and the Impact of Different DNMT3A Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia.

Gale RE, Lamb K, Allen C, El-Sharkawi D, Stowe C, Jenkinson S, Tinsley S, Dickson G, Burnett AK, Hills RK, Linch DC.

J Clin Oncol. 2015 Jun 20;33(18):2072-83. doi: 10.1200/JCO.2014.59.2022.


3-Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar.

Liu Z, Jenkinson SF, Vermaas T, Adachi I, Wormald MR, Hata Y, Kurashima Y, Kaji A, Yu CY, Kato A, Fleet GW.

J Org Chem. 2015 May 1;80(9):4244-58. doi: 10.1021/acs.joc.5b00463.


Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists.

Rouquet G, Moore DE, Spain M, Allwood DM, Battilocchio C, Blakemore DC, Fish PV, Jenkinson S, Jessiman AS, Ley SV, McMurray G, Storer RI.

ACS Med Chem Lett. 2015 Jan 20;6(3):329-33. doi: 10.1021/ml500507v.


Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic.

Goffinski A, Stanley MA, Shepherd N, Duvall N, Jenkinson SB, Davis C, Bull MJ, Roper RJ.

Am J Med Genet A. 2015 Feb;167A(2):324-30. doi: 10.1002/ajmg.a.36903.


'It's something you have to put up with'--service users' experiences of in utero transfer: a qualitative study.

Porcellato L, Masson G, O'Mahony F, Jenkinson S, Vanner T, Cheshire K, Perkins E.

BJOG. 2015 Dec;122(13):1825-32. doi: 10.1111/1471-0528.13235.


Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes.

Hayes EM, Tsaousi A, Di Gregoli K, Jenkinson SR, Bond AR, Johnson JL, Bevan L, Thomas AC, Newby AC.

Front Immunol. 2014 Oct 28;5:537. doi: 10.3389/fimmu.2014.00537.


Cyclin C is a haploinsufficient tumour suppressor.

Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, Liu L, Wang H, King B, Shaik S, Gutierrez A, Ordureau A, Otto T, Kreslavsky T, Baitsch L, Bury L, Meyer CA, Ke N, Mulry KA, Kluk MJ, Roy M, Kim S, Zhang X, Geng Y, Zagozdzon A, Jenkinson S, Gale RE, Linch DC, Zhao JJ, Mullighan CG, Harper JW, Aster JC, Aifantis I, von Boehmer H, Gygi SP, Wei W, Look AT, Sicinski P.

Nat Cell Biol. 2014 Nov;16(11):1080-91. doi: 10.1038/ncb3046.

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