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Items: 1 to 20 of 83


Silymarin in non-alcoholic steatohepatitis - a new kid on the block ?

Hupa KL, Jaeckel E, Manns MP.

Clin Gastroenterol Hepatol. 2017 Aug 10. pii: S1542-3565(17)30934-5. doi: 10.1016/j.cgh.2017.08.005. [Epub ahead of print] No abstract available.


Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance.

Nikolouli E, Hardtke-Wolenski M, Hapke M, Beckstette M, Geffers R, Floess S, Jaeckel E, Huehn J.

Front Immunol. 2017 Jun 28;8:748. doi: 10.3389/fimmu.2017.00748. eCollection 2017.


Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy.

Diestelhorst J, Junge N, Schlue J, Falk CS, Manns MP, Baumann U, Jaeckel E, Taubert R.

PLoS One. 2017 Jul 11;12(7):e0181107. doi: 10.1371/journal.pone.0181107. eCollection 2017.


Insulin degludec/liraglutide (IDegLira) was effective across a range of dysglycaemia and body mass index categories in the DUAL V randomized trial.

Lingvay I, Harris S, Jaeckel E, Chandarana K, Ranthe MF, Jódar E.

Diabetes Obes Metab. 2017 Jun 23. doi: 10.1111/dom.13043. [Epub ahead of print]


Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis.

Taubert R, Hardtke-Wolenski M, Noyan F, Lalanne C, Jonigk D, Schlue J, Krech T, Lichtinghagen R, Falk CS, Schlaphoff V, Bantel H, Muratori L, Manns MP, Jaeckel E.

PLoS One. 2017 Jun 8;12(6):e0179074. doi: 10.1371/journal.pone.0179074. eCollection 2017.


Sonderforschungsbereich SFB 738: Optimierung konventioneller und innovativer Transplantate.

Manns MP, Huber P, Jaeckel E.

Z Gastroenterol. 2017 Apr;55(4):401-404. doi: 10.1055/s-0043-101946. Epub 2017 Apr 20. German. No abstract available.


Rates of hypoglycaemia are lower in patients treated with insulin degludec/liraglutide (IDegLira) than with IDeg or insulin glargine, regardless of the hypoglycaemia definition used.

Norwood P, Chen R, Jaeckel E, Lingvay I, Jarlov H, Lehmann L, Heller S.

Diabetes Obes Metab. 2017 Apr 17. doi: 10.1111/dom.12972. [Epub ahead of print]


Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.

Garg G, Nikolouli E, Hardtke-Wolenski M, Toker A, Ohkura N, Beckstette M, Miyao T, Geffers R, Floess S, Gerdes N, Lutgens E, Osterloh A, Hori S, Sakaguchi S, Jaeckel E, Huehn J.

Oncotarget. 2017 May 30;8(22):35542-35557. doi: 10.18632/oncotarget.16221.


Home-based drainage of refractory ascites by a permanent-tunneled peritoneal catheter can safely replace large-volume paracentesis.

Solbach P, Höner Zu Siederdissen C, Taubert R, Ziegert S, Port K, Schneider A, Hueper K, Manns MP, Wedemeyer H, Jaeckel E.

Eur J Gastroenterol Hepatol. 2017 May;29(5):539-546. doi: 10.1097/MEG.0000000000000837.


Mechanisms creating transient and sustained photoresponses in mammalian retinal ganglion cells.

Zhao X, Reifler AN, Schroeder MM, Jaeckel ER, Chervenak AP, Wong KY.

J Gen Physiol. 2017 Mar 6;149(3):335-353. doi: 10.1085/jgp.201611720. Epub 2017 Feb 2.


Home-based drainage of refractory ascites by a permanent-tunneled peritoneal catheter can safely replace large-volume paracentesis.

Solbach P, Höner Zu Siederdissen C, Taubert R, Ziegert S, Port K, Schneider A, Hueper K, Manns MP, Wedemeyer H, Jaeckel E.

Eur J Gastroenterol Hepatol. 2017 Jan 21. doi: 10.1097/MEG.0000000000000837. [Epub ahead of print]


Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor.

Noyan F, Zimmermann K, Hardtke-Wolenski M, Knoefel A, Schulde E, Geffers R, Hust M, Huehn J, Galla M, Morgan M, Jokuszies A, Manns MP, Jaeckel E.

Am J Transplant. 2017 Apr;17(4):917-930. doi: 10.1111/ajt.14175. Epub 2017 Feb 6.


The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development.

Hardtke-Wolenski M, Dywicki J, Fischer K, Hapke M, Sievers M, Schlue J, Anderson MS, Taubert R, Noyan F, Manns MP, Jaeckel E.

J Autoimmun. 2017 Mar;78:39-45. doi: 10.1016/j.jaut.2016.12.001. Epub 2016 Dec 11.


Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?

Vondran FW, Schumacher C, Johanning K, Hartleben B, Knitsch W, Wiesner O, Jaeckel E, Manns MP, Klempnauer J, Bektas H, Lehner F.

Case Rep Transplant. 2016;2016:7074636. doi: 10.1155/2016/7074636. Epub 2016 May 4.


Preferential accumulation of T helper cells but not cytotoxic T cells characterizes benign subclinical rejection of human liver allografts.

Baumann AK, Schlue J, Noyan F, Hardtke-Wolenski M, Lehner F, Barg-Hock H, Klempnauer J, Manns MP, Taubert R, Jaeckel E.

Liver Transpl. 2016 Jul;22(7):943-55. doi: 10.1002/lt.24427.


Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated.

Taubert R, Danger R, Londoño MC, Christakoudi S, Martinez-Picola M, Rimola A, Manns MP, Sánchez-Fueyo A, Jaeckel E.

Am J Transplant. 2016 Apr;16(4):1285-93. doi: 10.1111/ajt.13617. Epub 2016 Feb 18.


All spiking, sustained ON displaced amacrine cells receive gap-junction input from melanopsin ganglion cells.

Reifler AN, Chervenak AP, Dolikian ME, Benenati BA, Li BY, Wachter RD, Lynch AM, Demertzis ZD, Meyers BS, Abufarha FS, Jaeckel ER, Flannery MP, Wong KY.

Curr Biol. 2015 Nov 2;25(21):2763-73. doi: 10.1016/j.cub.2015.09.018. Epub 2015 Oct 1. Erratum in: Curr Biol. 2015 Nov 2;25(21):2878.


Liver transplantation for critically Ill patients with secondary sclerosing cholangitis: Outcome and complications.

Voigtländer T, Jaeckel E, Lehner F, Manns MP, Lankisch TO.

Liver Transpl. 2015 Oct;21(10):1295-9. doi: 10.1002/lt.24192.


[Daytime flexible application of Insulin degludec in patients with type 1 diabetes or type 2 diabetes].

Lüdemann J, Milek K, Wilhelm B, Segner A, Jaeckel E.

MMW Fortschr Med. 2014 Oct 9;156 Suppl 3:89-97. German.


Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future.

Reichart B, Niemann H, Chavakis T, Denner J, Jaeckel E, Ludwig B, Marckmann G, Schnieke A, Schwinzer R, Seissler J, Tönjes RR, Klymiuk N, Wolf E, Bornstein SR.

Horm Metab Res. 2015 Jan;47(1):31-5. doi: 10.1055/s-0034-1395518. Epub 2014 Dec 15. Review.


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