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Items: 1 to 20 of 36


Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells.

Huh SJ, Clement K, Jee D, Merlini A, Choudhury S, Maruyama R, Yoo R, Chytil A, Boyle P, Ran FA, Moses HL, Barcellos-Hoff MH, Jackson-Grusby L, Meissner A, Polyak K.

Stem Cell Reports. 2015 Feb 10;4(2):297-311. doi: 10.1016/j.stemcr.2014.12.009. Epub 2015 Jan 22.


RUSH and CRUSH: a rapid and conditional RNA interference method in mice.

Brown JR, Zetsche B, Jackson-Grusby L.

Genesis. 2014 Jan;52(1):39-48. doi: 10.1002/dvg.22718. Epub 2013 Oct 26.


A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.

Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA; AACR Cancer Epigenome Task Force.

Cancer Res. 2012 Dec 15;72(24):6319-24. doi: 10.1158/0008-5472.CAN-12-3658. Epub 2012 Nov 27. No abstract available.


STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation.

Puram SV, Yeung CM, Jahani-Asl A, Lin C, de la Iglesia N, Konopka G, Jackson-Grusby L, Bonni A.

J Neurosci. 2012 Jun 6;32(23):7806-18. doi: 10.1523/JNEUROSCI.3243-11.2012.


The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma.

DesRochers TM, Shamis Y, Alt-Holland A, Kudo Y, Takata T, Wang G, Jackson-Grusby L, Garlick JA.

Epigenetics. 2012 Jan 1;7(1):34-46. doi: 10.4161/epi.7.1.18546. Epub 2012 Jan 1.


Moving AHEAD with an international human epigenome project.

American Association for Cancer Research Human Epigenome Task Force; European Union, Network of Excellence, Scientific Advisory Board.

Nature. 2008 Aug 7;454(7205):711-5. doi: 10.1038/454711a. No abstract available.


Suppression of intestinal neoplasia by deletion of Dnmt3b.

Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R.

Mol Cell Biol. 2006 Apr;26(8):2976-83.


Global loss of imprinting leads to widespread tumorigenesis in adult mice.

Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM 3rd, Jaenisch R.

Cancer Cell. 2005 Oct;8(4):275-85. Erratum in: Cancer Cell. 2005 Nov;8(5):433. Cancer Cell. 2006 Jan;9(1):69.


Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5. Epub 2005 Sep 8.


DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A.

Ma Y, Jacobs SB, Jackson-Grusby L, Mastrangelo MA, Torres-Betancourt JA, Jaenisch R, Rasmussen TP.

J Cell Sci. 2005 Apr 15;118(Pt 8):1607-16. Epub 2005 Mar 22.


Induction of tumors in mice by genomic hypomethylation.

Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R.

Science. 2003 Apr 18;300(5618):489-92.


Modeling cancer in mice.

Jackson-Grusby L.

Oncogene. 2002 Aug 12;21(35):5504-14. Review.


Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation.

Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R.

Nat Biotechnol. 2002 May;20(5):455-9.


Flp recombinase regulated lacZ expression at the ROSA26 locus.

Possemato R, Eggan K, Moeller BJ, Jaenisch R, Jackson-Grusby L.

Genesis. 2002 Feb;32(2):184-6. No abstract available.


Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation.

Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM 3rd, Yanagimachi R, Jaenisch R.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6209-14. Epub 2001 May 1.


Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation.

Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E, Jaenisch R.

Nat Genet. 2001 Jan;27(1):31-9.


Generation of mice from wild-type and targeted ES cells by nuclear cloning.

Rideout WM 3rd, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R.

Nat Genet. 2000 Feb;24(2):109-10. No abstract available.


Marking IL-4-producing cells by knock-in of the IL-4 gene.

Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ.

Int Immunol. 1999 Feb;11(2):243-7.


Decreased neonatal dietary fat absorption and T cell cytotoxicity in pancreatic lipase-related protein 2-deficient mice.

Lowe ME, Kaplan MH, Jackson-Grusby L, D'Agostino D, Grusby MJ.

J Biol Chem. 1998 Nov 20;273(47):31215-21.

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