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Items: 1 to 20 of 92


Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.

Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, Littau L, Jablonka S, Malhotra S, Topf M, Winter F, Davydova D, Lynch JW, Paige CJ, Alzheimer C, Harvey RJ, Villmann C.

J Neurosci. 2017 Aug 16;37(33):7948-7961. doi: 10.1523/JNEUROSCI.0009-17.2017. Epub 2017 Jul 19.


Developmental regulation of SMN expression: pathophysiological implications and perspectives for therapy development in spinal muscular atrophy.

Jablonka S, Sendtner M.

Gene Ther. 2017 Sep;24(9):506-513. doi: 10.1038/gt.2017.46. Epub 2017 May 30. Review.


C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.

Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, Lojewski X, Sterneckert J, Hermann A, Shaw PJ, Ince PG, Mann M, Meissner F, Sendtner M.

Nat Neurosci. 2016 Dec;19(12):1610-1618. doi: 10.1038/nn.4407. Epub 2016 Oct 10.


Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy.

Simon CM, Rauskolb S, Gunnersen JM, Holtmann B, Drepper C, Dombert B, Braga M, Wiese S, Jablonka S, Pühringer D, Zielasek J, Hoeflich A, Silani V, Wolf E, Kneitz S, Sommer C, Toyka KV, Sendtner M.

Acta Neuropathol. 2015 Sep;130(3):373-87. doi: 10.1007/s00401-015-1446-8. Epub 2015 May 30.


Cochlear nucleus whole mount explants promote the differentiation of neuronal stem cells from the cochlear nucleus in co-culture experiments.

Rak K, Völker J, Jürgens L, Völker C, Frenz S, Scherzad A, Schendzielorz P, Jablonka S, Mlynski R, Radeloff A, Hagen R.

Brain Res. 2015 Aug 7;1616:58-70. doi: 10.1016/j.brainres.2015.04.055. Epub 2015 May 8.


Mosaic pattern of Cre recombinase expression in cochlear outer hair cells of the Brn3.1 Cre mouse.

Frenz S, Rak K, Völker J, Jürgens L, Scherzad A, Schendzielorz P, Radeloff A, Jablonka S, Hansen S, Mlynski R, Hagen R.

Neuroreport. 2015 Apr 15;26(6):309-13. doi: 10.1097/WNR.0000000000000336.


Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons.

Dombert B, Sivadasan R, Simon CM, Jablonka S, Sendtner M.

PLoS One. 2014 Oct 22;9(10):e110846. doi: 10.1371/journal.pone.0110846. eCollection 2014.


Neurotrophic effects of taurine on spiral ganglion neurons in vitro.

Rak K, Völker J, Jürgens L, Scherzad A, Schendzielorz P, Radeloff A, Jablonka S, Mlynski R, Hagen R.

Neuroreport. 2014 Nov 12;25(16):1250-4. doi: 10.1097/WNR.0000000000000254.


Differentiation defects in primary motoneurons from a SMARD1 mouse model that are insensitive to treatment with low dose PEGylated IGF1.

Krieger F, Metzger F, Jablonka S.

Rare Dis. 2014 Jun 10;2:e29415. doi: 10.4161/rdis.29415. eCollection 2014.


Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus.

Rak K, Völker J, Frenz S, Scherzad A, Schendzielorz P, Radeloff A, Jablonka S, Hagen R, Mlynski R.

Neuroreport. 2014 Aug 20;25(12):960-4. doi: 10.1097/WNR.0000000000000220.


Axonal and dendritic localization of mRNAs for glycogen-metabolizing enzymes in cultured rodent neurons.

Pfeiffer-Guglielmi B, Dombert B, Jablonka S, Hausherr V, van Thriel C, Schöbel N, Jansen RP.

BMC Neurosci. 2014 Jun 4;15:70. doi: 10.1186/1471-2202-15-70.


Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1.

Krieger F, Elflein N, Saenger S, Wirthgen E, Rak K, Frantz S, Hoeflich A, Toyka KV, Metzger F, Jablonka S.

Brain. 2014 May;137(Pt 5):1374-93. doi: 10.1093/brain/awu059. Epub 2014 Mar 27.


Mutation of the TBCE gene causes disturbance of microtubules in the auditory nerve and cochlear outer hair cell degeneration accompanied by progressive hearing loss in the pmn/pmn mouse.

Rak K, Frenz S, Radeloff A, Groh J, Jablonka S, Martini R, Hagen R, Mlynski R.

Exp Neurol. 2013 Dec;250:333-40. doi: 10.1016/j.expneurol.2013.10.007. Epub 2013 Oct 10.


Mechanisms for axon maintenance and plasticity in motoneurons: alterations in motoneuron disease.

Jablonka S, Dombert B, Asan E, Sendtner M.

J Anat. 2014 Jan;224(1):3-14. doi: 10.1111/joa.12097. Epub 2013 Sep 6. Review.


Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ.

Krieger F, Elflein N, Ruiz R, Guerra J, Serrano AL, Asan E, Tabares L, Jablonka S.

Neurobiol Dis. 2013 Jun;54:169-82. doi: 10.1016/j.nbd.2012.12.010. Epub 2013 Jan 4.


Cell-autonomous axon growth of young motoneurons is triggered by a voltage-gated sodium channel.

Wetzel A, Jablonka S, Blum R.

Channels (Austin). 2013 Jan 1;7(1):51-6. doi: 10.4161/chan.23153. Epub 2012 Dec 13.


Role of Na(v)1.9 in activity-dependent axon growth in motoneurons.

Subramanian N, Wetzel A, Dombert B, Yadav P, Havlicek S, Jablonka S, Nassar MA, Blum R, Sendtner M.

Hum Mol Genet. 2012 Aug 15;21(16):3655-67. doi: 10.1093/hmg/dds195. Epub 2012 May 28.


Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis.

Ingram CJ, Weale ME, Plaster CA, Morrison KE, Goodall EF, Pall HS, Beck M, Jablonka S, Sendtner M, Fisher EM, Bradman N, Kasperavičiūtė D.

Amyotroph Lateral Scler. 2012 Jun;13(4):341-6. doi: 10.3109/17482968.2012.654394. Epub 2012 Mar 13.


Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease.

Jablonka S, Holtmann B, Sendtner M, Metzger F.

Exp Neurol. 2011 Dec;232(2):261-9. doi: 10.1016/j.expneurol.2011.09.015. Epub 2011 Sep 17.


Lectin-based isolation and culture of mouse embryonic motoneurons.

Conrad R, Jablonka S, Sczepan T, Sendtner M, Wiese S, Klausmeyer A.

J Vis Exp. 2011 Sep 15;(55). pii: 3200. doi: 10.3791/3200.

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