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Items: 1 to 20 of 86

1.

Recent developments of bioanalytical methods in determination of neurotransmitters in vivo.

Matys J, Gieroba B, Jóźwiak K.

J Pharm Biomed Anal. 2020 Feb 20;180:113079. doi: 10.1016/j.jpba.2019.113079. Epub 2019 Dec 24. Review.

PMID:
31896524
2.

Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapy.

Malek R, Maj M, Wnorowski A, Jóźwiak K, Martin H, Iriepa I, Moraleda I, Chabchoub F, Marco-Contelles J, Ismaili L.

Bioorg Chem. 2019 Oct;91:103205. doi: 10.1016/j.bioorg.2019.103205. Epub 2019 Aug 16.

PMID:
31446330
3.

3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice.

Targowska-Duda KM, Budzynska B, Michalak A, Jozwiak K, Biala G, Arias HR.

J Psychopharmacol. 2019 May;33(5):558-567. doi: 10.1177/0269881118821100. Epub 2019 Jan 15.

PMID:
30644335
4.

Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-( n-octylamino)pyrimidin-2(1 H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.

Trifonov L, Nudelman V, Zhenin M, Matsree E, Afri M, Schmerling B, Cohen G, Jozwiak K, Weitman M, Korshin E, Senderowitz H, Shainberg A, Hochhauser E, Gruzman A.

J Med Chem. 2018 Dec 27;61(24):11309-11326. doi: 10.1021/acs.jmedchem.8b01471. Epub 2018 Dec 11.

PMID:
30507195
5.

The presence and distribution of G protein-coupled receptor 35 (GPR35) in the human cornea - Evidences from in silico gene expression analysis and immunodetection.

Matysik-Woźniak A, Wnorowski A, Turski WA, Jóźwiak K, Jünemann A, Rejdak R.

Exp Eye Res. 2019 Feb;179:188-192. doi: 10.1016/j.exer.2018.11.011. Epub 2018 Nov 13.

PMID:
30445046
6.

Angiotensin II type 1 receptor blockers decrease kynurenic acid production in rat kidney in vitro.

Zakrocka I, Targowska-Duda KM, Wnorowski A, Kocki T, Jóźwiak K, Turski WA.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Feb;392(2):209-217. doi: 10.1007/s00210-018-1572-7. Epub 2018 Oct 29.

PMID:
30370429
7.

Influence of Cyclooxygenase-2 Inhibitors on Kynurenic Acid Production in Rat Brain in Vitro.

Zakrocka I, Targowska-Duda KM, Wnorowski A, Kocki T, Jóźwiak K, Turski WA.

Neurotox Res. 2019 Jan;35(1):244-254. doi: 10.1007/s12640-018-9952-9. Epub 2018 Sep 3.

8.

Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.

Chioua M, Buzzi E, Moraleda I, Iriepa I, Maj M, Wnorowski A, Giovannini C, Tramarin A, Portali F, Ismaili L, López-Alvarado P, Bolognesi ML, Jóźwiak K, Menéndez JC, Marco-Contelles J, Bartolini M.

Eur J Med Chem. 2018 Jul 15;155:839-846. doi: 10.1016/j.ejmech.2018.06.044. Epub 2018 Jun 19.

PMID:
29958119
9.

Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study.

Targowska-Duda KM, Kaczor AA, Jozwiak K, Arias HR.

J Biomol Struct Dyn. 2019 Feb;37(2):411-439. doi: 10.1080/07391102.2018.1427634. Epub 2018 Feb 16.

PMID:
29363414
10.

Molecular mechanism of action and safety of 5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione - a novel anticonvulsant drug candidate.

Kaproń B, Łuszczki J, Paneth A, Wujec M, Siwek A, Karcz T, Mordyl B, Głuch-Lutwin M, Gryboś A, Nowak G, Pająk K, Jóźwiak K, Tomczykowski A, Plech T.

Int J Med Sci. 2017 Jul 18;14(8):741-749. doi: 10.7150/ijms.20001. eCollection 2017.

11.

New approach in evaluation of ceramic-polymer composite bioactivity and biocompatibility.

Borkowski L, Sroka-Bartnicka A, Polkowska I, Pawlowska M, Palka K, Zieba E, Slosarczyk A, Jozwiak K, Ginalska G.

Anal Bioanal Chem. 2017 Sep;409(24):5747-5755. doi: 10.1007/s00216-017-0518-0. Epub 2017 Jul 26.

12.

GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.

Bernier M, Catazaro J, Singh NS, Wnorowski A, Boguszewska-Czubara A, Jozwiak K, Powers R, Wainer IW.

Int J Cancer. 2017 Nov 15;141(10):2131-2142. doi: 10.1002/ijc.30904. Epub 2017 Aug 7.

13.

Angiotensin II Type 1 Receptor Blockers Inhibit KAT II Activity in the Brain-Its Possible Clinical Applications.

Zakrocka I, Targowska-Duda KM, Wnorowski A, Kocki T, Jóźwiak K, Turski WA.

Neurotox Res. 2017 Nov;32(4):639-648. doi: 10.1007/s12640-017-9781-2. Epub 2017 Jul 21.

14.

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.

Matysik-Woźniak A, Jünemann A, Turski WA, Wnorowski A, Jóźwiak K, Paduch R, Okuno E, Moneta-Wielgoś J, Chorągiewicz T, Maciejewski R, Rejdak R.

Mol Vis. 2017 Jun 26;23:364-371. eCollection 2017.

15.

Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells.

Wnorowski A, Such J, Paul RK, Wersto RP, Indig FE, Jozwiak K, Bernier M, Wainer IW.

Cell Signal. 2017 Aug;36:176-188. doi: 10.1016/j.cellsig.2017.05.006. Epub 2017 May 8.

16.

Kynurenic Acid and Neuroprotective Activity of the Ketogenic Diet in the Eye.

Zarnowski T, Tulidowicz-Bielak M, Zarnowska I, Mitosek-Szewczyk K, Wnorowski A, Jozwiak K, Gasior M, Turski WA.

Curr Med Chem. 2017;24(32):3547-3558. doi: 10.2174/0929867324666170509120257. Review.

PMID:
28486923
17.

A vital region for human glycoprotein hormone trafficking revealed by an LHB mutation.

Potorac I, Rivero-Müller A, Trehan A, Kiełbus M, Jozwiak K, Pralong F, Hafidi A, Thiry A, Ménagé JJ, Huhtaniemi I, Beckers A, Daly AF.

J Endocrinol. 2016 Dec;231(3):197-207. Epub 2016 Sep 21.

18.

The impact of multiple sclerosis relapse treatment on migration of effector T cells--Preliminary study.

Jatczak-Pawlik I, Książek-Winiarek D, Wojkowska D, Jóźwiak K, Jastrzębski K, Pietruczuk M, Głąbiński A.

Neurol Neurochir Pol. 2016;50(3):155-62. doi: 10.1016/j.pjnns.2016.02.003. Epub 2016 Feb 20.

PMID:
27154441
19.

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

Arias HR, Ravazzini F, Targowska-Duda KM, Kaczor AA, Feuerbach D, Boffi JC, Draczkowski P, Montag D, Brown BM, Elgoyhen AB, Jozwiak K, Puia G.

Int J Biochem Cell Biol. 2016 Jul;76:19-30. doi: 10.1016/j.biocel.2016.04.015. Epub 2016 Apr 26.

PMID:
27129924
20.

Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells.

Singh NS, Rutkowska E, Plazinska A, Khadeer M, Moaddel R, Jozwiak K, Bernier M, Wainer IW.

PLoS One. 2016 Apr 20;11(4):e0149499. doi: 10.1371/journal.pone.0149499. eCollection 2016.

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