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Items: 1 to 20 of 427

1.

Sample Size Estimation for Alzheimer's Disease Trials from Japanese ADNI Serial Magnetic Resonance Imaging.

Fujishima M, Kawaguchi A, Maikusa N, Kuwano R, Iwatsubo T, Matsuda H; Japanese Alzheimer’s Disease Neuroimaging Initiative (ADNI).; Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI)..

J Alzheimers Dis. 2016 Nov 28. [Epub ahead of print]

PMID:
27911297
2.

Phantom criteria for qualification of brain FDG and amyloid PET across different cameras.

Ikari Y, Akamatsu G, Nishio T, Ishii K, Ito K, Iwatsubo T, Senda M.

EJNMMI Phys. 2016 Dec;3(1):23.

3.

Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.

Matsukawa K, Hashimoto T, Matsumoto T, Ihara R, Chihara T, Miura M, Wakabayashi T, Iwatsubo T.

J Biol Chem. 2016 Nov 4;291(45):23464-23476.

PMID:
27634045
4.

Partial loss of CALM function reduces Aβ42 production and amyloid deposition in vivo.

Kanatsu K, Hori Y, Takatori S, Watanabe T, Iwatsubo T, Tomita T.

Hum Mol Genet. 2016 Jul 27. pii: ddw239. [Epub ahead of print]

PMID:
27466196
5.

LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts.

Kuwahara T, Inoue K, D'Agati VD, Fujimoto T, Eguchi T, Saha S, Wolozin B, Iwatsubo T, Abeliovich A.

Sci Rep. 2016 Jul 18;6:29945. doi: 10.1038/srep29945.

6.

BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.

Miyagawa T, Ebinuma I, Morohashi Y, Hori Y, Young Chang M, Hattori H, Maehara T, Yokoshima S, Fukuyama T, Tsuji S, Iwatsubo T, Prendergast GC, Tomita T.

Hum Mol Genet. 2016 Jul 15;25(14):2948-2958.

PMID:
27179792
7.

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

Hayashi Y, Nishimune H, Hozumi K, Saga Y, Harada A, Yuzaki M, Iwatsubo T, Kopan R, Tomita T.

Sci Rep. 2016 Apr 4;6:23969. doi: 10.1038/srep23969.

8.

Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production.

Tominaga A, Cai T, Takagi-Niidome S, Iwatsubo T, Tomita T.

J Neurosci. 2016 Jan 27;36(4):1362-72. doi: 10.1523/JNEUROSCI.5090-14.2016.

9.

Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.

Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M.

Acta Neuropathol. 2016 Feb;131(2):267-80. doi: 10.1007/s00401-015-1503-3.

10.

Efficacy of recombinant human soluble thrombomodulin in preventing walled-off necrosis in severe acute pancreatitis patients.

Eguchi T, Tsuji Y, Yamashita H, Fukuchi T, Kanamori A, Matsumoto K, Hasegawa T, Koizumi A, Kitada R, Tsujimae M, Iwatsubo T, Koyama S, Ubukata S, Fujita M, Okada A.

Pancreatology. 2015 Sep-Oct;15(5):485-90. doi: 10.1016/j.pan.2015.08.002.

11.

Novel Prokinetic Acotiamide Reduces Transient Lower Esophageal Sphincter Relaxation in Healthy Subjects.

Yamashita H, Kanamori A, Fukuchi T, Tsujimae M, Koizumi A, Iwatsubo T, Koyama S, Eguchi T, Ubukata S, Fujita M, Okada A.

Digestion. 2015;92(2):90-8. doi: 10.1159/000437301.

PMID:
26279051
12.

The Worldwide Alzheimer's Disease Neuroimaging Initiative: An update.

Hendrix JA, Finger B, Weiner MW, Frisoni GB, Iwatsubo T, Rowe CC, Kim SY, Guinjoan SM, Sevlever G, Carrillo MC.

Alzheimers Dement. 2015 Jul;11(7):850-9. doi: 10.1016/j.jalz.2015.05.008. Review.

PMID:
26194318
13.

Formation of Hydroxyapatite Skeletal Materials from Hydrogel Matrices via Artificial Biomineralization.

Iwatsubo T, Kishi R, Miura T, Ohzono T, Yamaguchi T.

J Phys Chem B. 2015 Jul 16;119(28):8793-9. doi: 10.1021/acs.jpcb.5b03181.

PMID:
26101802
14.

Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease.

Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS; Alzheimer’s Disease Cooperative Study..

Alzheimers Res Ther. 2015 Jun 10;7(1):36. doi: 10.1186/s13195-015-0121-6.

15.

Chronic optogenetic activation augments aβ pathology in a mouse model of Alzheimer disease.

Yamamoto K, Tanei Z, Hashimoto T, Wakabayashi T, Okuno H, Naka Y, Yizhar O, Fenno LE, Fukayama M, Bito H, Cirrito JR, Holtzman DM, Deisseroth K, Iwatsubo T.

Cell Rep. 2015 May 12;11(6):859-65. doi: 10.1016/j.celrep.2015.04.017.

16.

Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO.

Hori Y, Hashimoto T, Nomoto H, Hyman BT, Iwatsubo T.

J Biol Chem. 2015 Jun 12;290(24):15163-74. doi: 10.1074/jbc.M114.622209.

17.

Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.

Kukharsky MS, Quintiero A, Matsumoto T, Matsukawa K, An H, Hashimoto T, Iwatsubo T, Buchman VL, Shelkovnikova TA.

Mol Neurodegener. 2015 Apr 10;10:20. doi: 10.1186/s13024-015-0014-y.

18.

Cooperative roles of hydrophilic loop 1 and the C-terminus of presenilin 1 in the substrate-gating mechanism of γ-secretase.

Takagi-Niidome S, Sasaki T, Osawa S, Sato T, Morishima K, Cai T, Iwatsubo T, Tomita T.

J Neurosci. 2015 Feb 11;35(6):2646-56. doi: 10.1523/JNEUROSCI.3164-14.2015.

19.

Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity.

Takasugi N, Sasaki T, Shinohara M, Iwatsubo T, Tomita T.

Biochem Biophys Res Commun. 2015 Feb 6;457(2):194-9. doi: 10.1016/j.bbrc.2014.12.087.

PMID:
25545059
20.

Imago Mundi, Imago AD, Imago ADNI.

Villemagne VL, Kim SY, Rowe CC, Iwatsubo T.

Alzheimers Res Ther. 2014 Aug 29;6(5):62. doi: 10.1186/s13195-014-0062-5. Review.

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