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Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.

Sun Y, Peng I, Webster JD, Suto E, Lesch J, Wu X, Senger K, Francis G, Barrett K, Collier JL, Burch JD, Zhou M, Chen Y, Chan C, Eastham-Anderson J, Ngu H, Li O, Staton T, Havnar C, Jaochico A, Jackman J, Jeet S, Riol-Blanco L, Wu LC, Choy DF, Arron JR, McKenzie BS, Ghilardi N, Ismaili MH, Pei Z, DeVoss J, Austin CD, Lee WP, Zarrin AA.

Sci Signal. 2015 Dec 1;8(405):ra122. doi: 10.1126/scisignal.aab0949.


Thermophilic bacteria in Moroccan hot springs, salt marshes and desert soils.

Aanniz T, Ouadghiri M, Melloul M, Swings J, Elfahime E, Ibijbijen J, Ismaili M, Amar M.

Braz J Microbiol. 2015 Jun 1;46(2):443-53. doi: 10.1590/S1517-838246220140219. eCollection 2015 Jun.


Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.

Burch JD, Barrett K, Chen Y, DeVoss J, Eigenbrot C, Goldsmith R, Ismaili MH, Lau K, Lin Z, Ortwine DF, Zarrin AA, McEwan PA, Barker JJ, Ellebrandt C, Kordt D, Stein DB, Wang X, Chen Y, Hu B, Xu X, Yuen PW, Zhang Y, Pei Z.

J Med Chem. 2015 May 14;58(9):3806-16. doi: 10.1021/jm501998m. Epub 2015 Apr 16.


[Intestinal hemangioma: an unusual cause of unexplained gastrointestinal bleeding, a case report].

Kharrasse G, Hadjkacem H, Azouguagh R, Soufi M, El Malki O, Ismaili ME, Mohcine R, Ifrine L, Belkouchi A.

Pan Afr Med J. 2014 Sep 24;19:64. doi: 10.11604/pamj.2014.19.64.4665. eCollection 2014. French. No abstract available.


Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK).

Trani G, Barker JJ, Bromidge SM, Brookfield FA, Burch JD, Chen Y, Eigenbrot C, Heifetz A, Ismaili MH, Johnson A, Krülle TM, MacKinnon CH, Maghames R, McEwan PA, Montalbetti CA, Ortwine DF, Pérez-Fuertes Y, Vaidya DG, Wang X, Zarrin AA, Pei Z.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5818-23. doi: 10.1016/j.bmcl.2014.10.020. Epub 2014 Oct 12.


Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.

Burch JD, Lau K, Barker JJ, Brookfield F, Chen Y, Chen Y, Eigenbrot C, Ellebrandt C, Ismaili MH, Johnson A, Kordt D, MacKinnon CH, McEwan PA, Ortwine DF, Stein DB, Wang X, Winkler D, Yuen PW, Zhang Y, Zarrin AA, Pei Z.

J Med Chem. 2014 Jul 10;57(13):5714-27. doi: 10.1021/jm500550e. Epub 2014 Jun 27.


Influence of surface anchoring conditions on the dielectric and electro-optical properties of nematic droplets dispersed in a polymer network.

Boussoualem M, Ismaili M, Roussel F.

Soft Matter. 2014 Jan 14;10(2):367-73. doi: 10.1039/c3sm52573b.


Spontaneous rupture of subclavian intraport catheter with cardiac and pulmonary embolism.

Ababou A, Ztot S, Ismaili MH, Elhassani A.

J Cardiothorac Vasc Anesth. 2013 Apr;27(2):e10-1. doi: 10.1053/j.jvca.2012.10.012. Epub 2013 Jan 10. No abstract available.


Prevention of Intra-operative Cerebral Ischemia during Carotid Endarterectomy, Loco-regional versus General Anesthesia.

Tawfic QA, Ismaili MA, Ahmed MA.

Oman Med J. 2012 May;27(3):254-5. doi: 10.5001/omj.2012.59.


Linear and non-linear dielectric properties of a short-pitch ferroelectric liquid crystal stabilized by a polymer network.

Cherfi Y, Hemine J, Douali R, Beldjoudi N, Ismaili M, Leblond JM, Legrand C, Daoudi A.

Eur Phys J E Soft Matter. 2010 Dec;33(4):335-42. doi: 10.1140/epje/i2010-10679-x. Epub 2010 Nov 25.


Anthracycline and concurrent radiotherapy as adjuvant treatment of operable breast cancer: a retrospective cohort study in a single institution.

Ismaili N, Elmajjaoui S, Lalya I, Boulaamane L, Belbaraka R, Abahssain H, Aassab R, Benjaafar N, El Guddari Bel K, El Mesbahi O, Sbitti Y, Ismaili M, Errihani H.

BMC Res Notes. 2010 Oct 4;3:247. doi: 10.1186/1756-0500-3-247.


Factors of interrupting chemotherapy in patients with Advanced Non-Small-Cell Lung Cancer.

Belbaraka R, Trédan O, Ray-Coquard I, Chvetzoff G, Bajard A, Pérol D, Ismaili N, Ismaili M, Errihani H, Bachelot T, Rebattu P.

BMC Res Notes. 2010 Jun 10;3:164. doi: 10.1186/1756-0500-3-164.


Primary Nasopharyngeal non-Hodgkin lymphomas: a retrospective review of 26 Moroccan patients.

Allam W, Ismaili N, Elmajjaoui S, Elgueddari BK, Ismaili M, Errihani H.

BMC Ear Nose Throat Disord. 2009 Nov 17;9:11. doi: 10.1186/1472-6815-9-11.


Outcome of recurrent and metastatic small cell carcinoma of the bladder.

Ismaili N, Heudel PE, Elkarak F, Kaikani W, Bajard A, Ismaili M, Errihani H, Droz JP, Flechon A.

BMC Urol. 2009 Jun 6;9:4. doi: 10.1186/1471-2490-9-4.


Effect of the network density on dynamics of the soft and the Goldstone modes in short-pitch ferroelectric liquid crystals stabilized by an anisotropic polymer network.

Petit M, Hemine J, Daoudi A, Ismaili M, Buisine JM, Da Costa A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Mar;79(3 Pt 1):031705. Epub 2009 Mar 30.


Concurrent chemoradiotherapy in adjuvant treatment of breast cancer.

Ismaili N, Mellas N, Masbah O, Elmajjaoui S, Arifi S, Bekkouch I, Ahid S, Bazid Z, Tazi MA, Erraki A, El Mesbahi O, Benjaafar N, El Gueddari Bel K, Ismaili M, Afqir S, Errihani H.

Radiat Oncol. 2009 Apr 7;4:12. doi: 10.1186/1748-717X-4-12.


Mechanisms of morphine enhancement of spontaneous seizure activity.

Saboory E, Derchansky M, Ismaili M, Jahromi SS, Brull R, Carlen PL, El Beheiry H.

Anesth Analg. 2007 Dec;105(6):1729-35, table of contents.


Electroclinic effect in a chiral smectic-A liquid crystal stabilized by an anisotropic polymer network.

Petit M, Daoudi A, Ismaili M, Buisine JM.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Dec;74(6 Pt 1):061707. Epub 2006 Dec 27.


Distortion and unwinding of the helical structure in polymer-stabilized short-pitch ferroelectric liquid crystal.

Petit M, Daoudi A, Ismaili M, Buisine JM.

Eur Phys J E Soft Matter. 2006 Jul;20(3):327-33. Epub 2006 Jul 25.


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