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Items: 1 to 20 of 202


Fear Learning Regulates Cortical Sensory Representations by Suppressing Habituation.

Gillet SN, Kato HK, Justen MA, Lai M, Isaacson JS.

Front Neural Circuits. 2018 Jan 10;11:112. doi: 10.3389/fncir.2017.00112. eCollection 2017.


PSMA-targeted bispecific Fab conjugates that engage T cells.

Patterson JT, Isaacson J, Kerwin L, Atassi G, Duggal R, Bresson D, Zhu T, Zhou H, Fu Y, Kaufmann GF.

Bioorg Med Chem Lett. 2017 Dec 15;27(24):5490-5495. doi: 10.1016/j.bmcl.2017.09.065. Epub 2017 Oct 6.


Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial.

Coleman RL, Oza AM, Lorusso D, Aghajanian C, Oaknin A, Dean A, Colombo N, Weberpals JI, Clamp A, Scambia G, Leary A, Holloway RW, Gancedo MA, Fong PC, Goh JC, O'Malley DM, Armstrong DK, Garcia-Donas J, Swisher EM, Floquet A, Konecny GE, McNeish IA, Scott CL, Cameron T, Maloney L, Isaacson J, Goble S, Grace C, Harding TC, Raponi M, Sun J, Lin KK, Giordano H, Ledermann JA; ARIEL3 investigators.

Lancet. 2017 Oct 28;390(10106):1949-1961. doi: 10.1016/S0140-6736(17)32440-6. Epub 2017 Sep 12.


Digest: Premating barriers drive reproductive isolation between two damselfly species.

Isaacson J.

Evolution. 2017 Oct;71(10):2541-2542. doi: 10.1111/evo.13331. Epub 2017 Sep 13. No abstract available.


Digest: Does intralocus sexual conflict affect cricket nutrition?

Isaacson J.

Evolution. 2017 Sep;71(9):2271-2272. doi: 10.1111/evo.13319. Epub 2017 Aug 9. No abstract available.


Network-Level Control of Frequency Tuning in Auditory Cortex.

Kato HK, Asinof SK, Isaacson JS.

Neuron. 2017 Jul 19;95(2):412-423.e4. doi: 10.1016/j.neuron.2017.06.019. Epub 2017 Jul 6.


A Professionalism Curricular Model to Promote Transformative Learning Among Residents.

Foshee CM, Mehdi A, Bierer SB, Traboulsi EI, Isaacson JH, Spencer A, Calabrese C, Burkey BB.

J Grad Med Educ. 2017 Jun;9(3):351-356. doi: 10.4300/JGME-D-16-00421.1.


Training internal medicine residents to manage chronic pain and prescription opioid misuse.

Ruff AL, Alford DP, Butler R, Isaacson JH.

Subst Abus. 2017 Apr-Jun;38(2):200-204. doi: 10.1080/08897077.2017.1296526. Epub 2017 Apr 10.


A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors.

Kristeleit R, Shapiro GI, Burris HA, Oza AM, LoRusso P, Patel MR, Domchek SM, BalmaƱa J, Drew Y, Chen LM, Safra T, Montes A, Giordano H, Maloney L, Goble S, Isaacson J, Xiao J, Borrow J, Rolfe L, Shapira-Frommer R.

Clin Cancer Res. 2017 Aug 1;23(15):4095-4106. doi: 10.1158/1078-0432.CCR-16-2796. Epub 2017 Mar 6.


Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.

Swisher EM, Lin KK, Oza AM, Scott CL, Giordano H, Sun J, Konecny GE, Coleman RL, Tinker AV, O'Malley DM, Kristeleit RS, Ma L, Bell-McGuinn KM, Brenton JD, Cragun JM, Oaknin A, Ray-Coquard I, Harrell MI, Mann E, Kaufmann SH, Floquet A, Leary A, Harding TC, Goble S, Maloney L, Isaacson J, Allen AR, Rolfe L, Yelensky R, Raponi M, McNeish IA.

Lancet Oncol. 2017 Jan;18(1):75-87. doi: 10.1016/S1470-2045(16)30559-9. Epub 2016 Nov 29.


Clinicians' Perspectives and Experiences Regarding Maternity Care in Women With Vulvodynia.

Smith KB, Sadownik LA, Basson R, Isaacson J, Brotto LA.

J Obstet Gynaecol Can. 2016 Sep;38(9):811-819. doi: 10.1016/j.jogc.2016.04.008. Epub 2016 Jun 11.


Flexible Sensory Representations in Auditory Cortex Driven by Behavioral Relevance.

Kato HK, Gillet SN, Isaacson JS.

Neuron. 2015 Dec 2;88(5):1027-1039. doi: 10.1016/j.neuron.2015.10.024. Epub 2015 Nov 12.


A 79-year-old with acute portal vein thrombosis.

Zhu L, Gornik H, Isaacson JH.

Cleve Clin J Med. 2015 May;82(5):287-93. doi: 10.3949/ccjm.82a.14028. No abstract available.


Rociletinib in EGFR-mutated non-small-cell lung cancer.

Sequist LV, Soria JC, Goldman JW, Wakelee HA, Gadgeel SM, Varga A, Papadimitrakopoulou V, Solomon BJ, Oxnard GR, Dziadziuszko R, Aisner DL, Doebele RC, Galasso C, Garon EB, Heist RS, Logan J, Neal JW, Mendenhall MA, Nichols S, Piotrowska Z, Wozniak AJ, Raponi M, Karlovich CA, Jaw-Tsai S, Isaacson J, Despain D, Matheny SL, Rolfe L, Allen AR, Camidge DR.

N Engl J Med. 2015 Apr 30;372(18):1700-9. doi: 10.1056/NEJMoa1413654.


Physiology of Mechanotransduction: How Do Muscle and Bone "Talk" to One Another?

Isaacson J, Brotto M.

Clin Rev Bone Miner Metab. 2014 Jun;12(2):77-85.


Somatostatin cells regulate sensory response fidelity via subtractive inhibition in olfactory cortex.

Sturgill JF, Isaacson JS.

Nat Neurosci. 2015 Apr;18(4):531-5. doi: 10.1038/nn.3971. Epub 2015 Mar 9.


Broadcasting of cortical activity to the olfactory bulb.

Boyd AM, Kato HK, Komiyama T, Isaacson JS.

Cell Rep. 2015 Feb 24;10(7):1032-9. doi: 10.1016/j.celrep.2015.01.047. Epub 2015 Feb 19.


Creatine phosphokinase elevation exacerbated by levetiracetam therapy.

Isaacson JE, Choe DJ, Doherty MJ.

Epilepsy Behav Case Rep. 2014 Oct 22;2:189-91. doi: 10.1016/j.ebcr.2014.09.008. eCollection 2014.


Single dendrite-targeting interneurons generate branch-specific inhibition.

Stokes CC, Teeter CM, Isaacson JS.

Front Neural Circuits. 2014 Nov 25;8:139. doi: 10.3389/fncir.2014.00139. eCollection 2014.


Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.

Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, Guicherit O, Wouters BG, O'Brien CA, Shields D, Olson P, VanArsdale T, Weinrich SL, Rejto P, Christensen JG, Fantin VR, Hung KE, Martin ES.

Sci Signal. 2014 Nov 11;7(351):ra107. doi: 10.1126/scisignal.2005516.


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