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Items: 1 to 20 of 136

1.

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.

Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, McCoy LE, Oom AL, Ozorowski G, Post KW, Sharma SK, Steichen JM, de Taeye SW, Tokatlian T, Torrents de la Peña A, Butera ST, LaBranche CC, Montefiori DC, Silvestri G, Wilson IA, Irvine DJ, Sanders RW, Schief WR, Ward AB, Wyatt RT, Barouch DH, Crotty S, Burton DR.

Immunity. 2017 Jun 20;46(6):1073-1088.e6. doi: 10.1016/j.immuni.2017.05.007.

2.

Delivering safer immunotherapies for cancer.

Milling L, Zhang Y, Irvine DJ.

Adv Drug Deliv Rev. 2017 May 22. pii: S0169-409X(17)30067-4. doi: 10.1016/j.addr.2017.05.011. [Epub ahead of print]

3.

Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors.

Zheng Y, Tang L, Mabardi L, Kumari S, Irvine DJ.

ACS Nano. 2017 Mar 28;11(3):3089-3100. doi: 10.1021/acsnano.7b00078. Epub 2017 Mar 1.

PMID:
28231431
4.

Nanoscience and Nanotechnology Cross Borders.

Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad O, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS.

ACS Nano. 2017 Feb 28;11(2):1123-1126. doi: 10.1021/acsnano.7b00953. Epub 2017 Feb 15. No abstract available.

PMID:
28199099
5.

Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery.

Li J, Wang W, He Y, Li Y, Yan EZ, Zhang K, Irvine DJ, Hammond PT.

ACS Nano. 2017 Mar 28;11(3):2531-2544. doi: 10.1021/acsnano.6b08447. Epub 2017 Feb 14.

PMID:
28157292
6.

Smart Radiation Therapy Biomaterials.

Ngwa W, Boateng F, Kumar R, Irvine DJ, Formenti S, Ngoma T, Herskind C, Veldwijk MR, Hildenbrand GL, Hausmann M, Wenz F, Hesser J.

Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):624-637. doi: 10.1016/j.ijrobp.2016.10.034. Epub 2016 Nov 1. Review.

PMID:
28126309
7.

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry.

Yang YS, Atukorale PU, Moynihan KD, Bekdemir A, Rakhra K, Tang L, Stellacci F, Irvine DJ.

Nat Commun. 2017 Jan 17;8:14069. doi: 10.1038/ncomms14069.

8.

Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy.

Griffiths KL, Ahmed M, Das S, Gopal R, Horne W, Connell TD, Moynihan KD, Kolls JK, Irvine DJ, Artyomov MN, Rangel-Moreno J, Khader SA.

Nat Commun. 2016 Dec 22;7:13894. doi: 10.1038/ncomms13894.

9.

Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells.

Jones RB, Mueller S, Kumari S, Vrbanac V, Genel S, Tager AM, Allen TM, Walker BD, Irvine DJ.

Biomaterials. 2017 Feb;117:44-53. doi: 10.1016/j.biomaterials.2016.11.048. Epub 2016 Nov 25.

PMID:
27936416
10.

Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy.

Tzeng A, Kauke MJ, Zhu EF, Moynihan KD, Opel CF, Yang NJ, Mehta N, Kelly RL, Szeto GL, Overwijk WW, Irvine DJ, Wittrup KD.

Cell Rep. 2016 Dec 6;17(10):2503-2511. doi: 10.1016/j.celrep.2016.11.020.

11.

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.

Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, Mehta NK, Kauke MJ, Suh H, Cochran JR, Lauffenburger DA, Wittrup KD, Irvine DJ.

Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24.

12.

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.

Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. Epub 2016 Oct 4.

13.

Synthesis of Lymph Node-Targeting Adjuvants.

Hanson MC, Irvine DJ.

Methods Mol Biol. 2017;1494:145-152.

PMID:
27718191
14.

Using Diurnal Temperature Signals to Infer Vertical Groundwater-Surface Water Exchange.

Irvine DJ, Briggs MA, Lautz LK, Gordon RP, McKenzie JM, Cartwright I.

Ground Water. 2017 Jan;55(1):10-26. doi: 10.1111/gwat.12459. Epub 2016 Oct 3. Review.

PMID:
27696430
15.

Groundwater flow estimation using temperature-depth profiles in a complex environment and a changing climate.

Irvine DJ, Kurylyk BL, Cartwright I, Bonham M, Post VE, Banks EW, Simmons CT.

Sci Total Environ. 2017 Jan 1;574:272-281. doi: 10.1016/j.scitotenv.2016.08.212. Epub 2016 Oct 14.

PMID:
27639024
16.

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.

Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, Menis S, Georgeson E, Kubitz M, Adachi Y, Jones M, Mutafyan AA, Yun DS, Mayer CT, Ward AB, Burton DR, Wilson IA, Irvine DJ, Nussenzweig MC, Schief WR.

Immunity. 2016 Sep 20;45(3):483-96. doi: 10.1016/j.immuni.2016.08.016. Epub 2016 Sep 8.

17.

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, Hartwig J, Irvine DJ, Luscinskas FW, Geha RS.

J Clin Invest. 2016 Oct 3;126(10):3837-3851. doi: 10.1172/JCI85774. Epub 2016 Sep 6.

18.

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.

Donius LR, Cheng Y, Choi J, Sun ZY, Hanson M, Zhang M, Gierahn TM, Marquez S, Uduman M, Kleinstein SH, Irvine D, Love JC, Reinherz EL, Kim M.

J Virol. 2016 Sep 12;90(19):8875-90. doi: 10.1128/JVI.01089-16. Print 2016 Oct 1.

19.

Improved Vertical Streambed Flux Estimation Using Multiple Diurnal Temperature Methods in Series.

Irvine DJ, Briggs MA, Cartwright I, Scruggs CR, Lautz LK.

Ground Water. 2017 Jan;55(1):73-80. doi: 10.1111/gwat.12436. Epub 2016 Jun 22.

PMID:
27331372
20.

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.

Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, Buzon MJ, Lichterfeld M, Irrinki A, Murry JP, Tsai A, Yu H, Geleziunas R, Trocha A, Ostrowski MA, Irvine DJ, Walker BD.

PLoS Pathog. 2016 Apr 15;12(4):e1005545. doi: 10.1371/journal.ppat.1005545. eCollection 2016 Apr.

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