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Items: 1 to 20 of 171


Polycomb enables primitive endoderm lineage priming in embryonic stem cells.

Illingworth RS, Hölzenspies JJ, Roske FV, Bickmore WA, Brickman JM.

Elife. 2016 Oct 10;5. pii: e14926. doi: 10.7554/eLife.14926.


Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.

Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR.

Cancer Res. 2016 May 15;76(10):3097-108. doi: 10.1158/0008-5472.CAN-15-1910. Epub 2016 Apr 6.


Polycomb-mediated chromatin compaction weathers the STORM.

Williamson I, Bickmore WA, Illingworth RS.

Genome Biol. 2016 Feb 25;17:35. doi: 10.1186/s13059-016-0899-y.


The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development.

Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA.

Genes Dev. 2015 Sep 15;29(18):1897-902. doi: 10.1101/gad.268151.115.


Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.

Illingworth RS, Gruenewald-Schneider U, De Sousa D, Webb S, Merusi C, Kerr AR, James KD, Smith C, Walker R, Andrews R, Bird AP.

Nucleic Acids Res. 2015 Jan;43(2):732-44. doi: 10.1093/nar/gku1305. Epub 2015 Jan 8.


Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization.

Williamson I, Berlivet S, Eskeland R, Boyle S, Illingworth RS, Paquette D, Dostie J, Bickmore WA.

Genes Dev. 2014 Dec 15;28(24):2778-91. doi: 10.1101/gad.251694.114.


Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells.

Therizols P, Illingworth RS, Courilleau C, Boyle S, Wood AJ, Bickmore WA.

Science. 2014 Dec 5;346(6214):1238-42. doi: 10.1126/science.1259587.


PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.

Illingworth RS, Botting CH, Grimes GR, Bickmore WA, Eskeland R.

PLoS One. 2012;7(4):e34848. doi: 10.1371/journal.pone.0034848. Epub 2012 Apr 9.


Cell type-specific DNA methylation at intragenic CpG islands in the immune system.

Deaton AM, Webb S, Kerr AR, Illingworth RS, Guy J, Andrews R, Bird A.

Genome Res. 2011 Jul;21(7):1074-86. doi: 10.1101/gr.118703.110. Epub 2011 May 31.


Immunostaining of modified histones defines high-level features of the human metaphase epigenome.

Terrenoire E, McRonald F, Halsall JA, Page P, Illingworth RS, Taylor AM, Davison V, O'Neill LP, Turner BM.

Genome Biol. 2010;11(11):R110. doi: 10.1186/gb-2010-11-11-r110. Epub 2010 Nov 15.


Orphan CpG islands identify numerous conserved promoters in the mammalian genome.

Illingworth RS, Gruenewald-Schneider U, Webb S, Kerr AR, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.

PLoS Genet. 2010 Sep 23;6(9):e1001134. doi: 10.1371/journal.pgen.1001134.


Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP.

Mol Cell. 2010 Feb 26;37(4):457-68. doi: 10.1016/j.molcel.2010.01.030.


CpG islands--'a rough guide'.

Illingworth RS, Bird AP.

FEBS Lett. 2009 Jun 5;583(11):1713-20. doi: 10.1016/j.febslet.2009.04.012. Epub 2009 Apr 18. Review.


Why irritated?

Illingworth RS.

Arch Dis Child. 1988 May;63(5):567-8. No abstract available.


Pitfalls in developmental diagnosis.

Illingworth RS.

Arch Dis Child. 1987 Aug;62(8):860-5.


Anaemia and child health surveillance.

Illingworth RS.

Arch Dis Child. 1986 Dec;61(12):1151-2. No abstract available.


Developmental surveillance.

Illingworth RS.

Lancet. 1986 May 24;1(8491):1209. No abstract available.


Norms for development.

Illingworth RS.

Dev Med Child Neurol. 1986 Feb;28(1):122-3. No abstract available.


Infantile colic revisited.

Illingworth RS.

Arch Dis Child. 1985 Oct;60(10):981-5. No abstract available.


A paediatrician asks--why is it called birth injury?

Illingworth RS.

Br J Obstet Gynaecol. 1985 Feb;92(2):122-30. Review.


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