Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 108

1.

Mechanism of Fibrosis in HNF1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease.

Chan SC, Zhang Y, Shao A, Avdulov S, Herrera J, Aboudehen K, Pontoglio M, Igarashi P.

J Am Soc Nephrol. 2018 Oct;29(10):2493-2509. doi: 10.1681/ASN.2018040437. Epub 2018 Aug 10.

PMID:
30097458
2.

New insights into the role of HNF-1β in kidney (patho)physiology.

Ferrè S, Igarashi P.

Pediatr Nephrol. 2018 Jul 1. doi: 10.1007/s00467-018-3990-7. [Epub ahead of print] Review.

PMID:
29961928
3.

Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.

Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P.

J Biol Chem. 2018 Jun 15;293(24):9388-9398. doi: 10.1074/jbc.RA118.001723. Epub 2018 May 1.

PMID:
29716997
4.

Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria.

Wong DWL, Yiu WH, Chan KW, Li Y, Li B, Lok SWY, Taketo MM, Igarashi P, Chan LYY, Leung JCK, Lai KN, Tang SCW.

Kidney Int. 2018 Jun;93(6):1367-1383. doi: 10.1016/j.kint.2017.12.017. Epub 2018 Mar 28.

PMID:
29605095
5.

Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.

Wang Q, Cobo-Stark P, Patel V, Somlo S, Han PL, Igarashi P.

Kidney Int. 2018 Feb;93(2):403-415. doi: 10.1016/j.kint.2017.08.005. Epub 2017 Oct 14.

PMID:
29042084
6.

Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease.

Kompatscher A, de Baaij JHF, Aboudehen K, Hoefnagels APWM, Igarashi P, Bindels RJM, Veenstra GJC, Hoenderop JGJ.

Kidney Int. 2017 Nov;92(5):1145-1156. doi: 10.1016/j.kint.2017.03.034. Epub 2017 May 31.

PMID:
28577853
7.

Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.

Aboudehen K, Noureddine L, Cobo-Stark P, Avdulov S, Farahani S, Gearhart MD, Bichet DG, Pontoglio M, Patel V, Igarashi P.

J Am Soc Nephrol. 2017 Oct;28(10):2887-2900. doi: 10.1681/ASN.2016101095. Epub 2017 May 15.

8.

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.

Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V.

Nat Commun. 2017 Feb 16;8:14395. doi: 10.1038/ncomms14395.

9.

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.

Brzóska HŁ, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA.

Kidney Int. 2016 Dec;90(6):1274-1284. doi: 10.1016/j.kint.2016.07.011. Epub 2016 Sep 2.

10.

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease.

Lu D, Rauhauser A, Li B, Ren C, McEnery K, Zhu J, Chaki M, Vadnagara K, Elhadi S, Jetten AM, Igarashi P, Attanasio M.

Kidney Int. 2016 Jun;89(6):1307-23. doi: 10.1016/j.kint.2016.03.006.

11.

Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.

Aboudehen K, Kim MS, Mitsche M, Garland K, Anderson N, Noureddine L, Pontoglio M, Patel V, Xie Y, DeBose-Boyd R, Igarashi P.

J Am Soc Nephrol. 2016 Aug;27(8):2408-21. doi: 10.1681/ASN.2015060607. Epub 2015 Dec 28.

12.

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA.

Hajarnis SS, Patel V, Aboudehen K, Attanasio M, Cobo-Stark P, Pontoglio M, Igarashi P.

J Biol Chem. 2015 Oct 9;290(41):24793-805. doi: 10.1074/jbc.M115.670646. Epub 2015 Aug 19.

13.

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

Boddu R, Yang C, O'Connor AK, Hendrickson RC, Boone B, Cui X, Garcia-Gonzalez M, Igarashi P, Onuchic LF, Germino GG, Guay-Woodford LM.

J Mol Med (Berl). 2014 Oct;92(10):1045-56. doi: 10.1007/s00109-014-1185-7. Epub 2014 Jul 3.

14.

Filling the holes in cystic kidney disease research.

Guay-Woodford LM, Henske E, Igarashi P, Perrone RD, Reed-Gitomer B, Somlo S, Torres VE, Ketchum CJ, Star RA, Flessner MF, Rasooly RS.

Clin J Am Soc Nephrol. 2014 Oct 7;9(10):1799-801. doi: 10.2215/CJN.03410414. Epub 2014 Jun 5. Review.

15.

Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter.

Williams SS, Cobo-Stark P, Hajarnis S, Aboudehen K, Shao X, Richardson JA, Patel V, Igarashi P.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F356-68. doi: 10.1152/ajprenal.00422.2013. Epub 2014 Jun 4.

16.

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.

Ma M, Tian X, Igarashi P, Pazour GJ, Somlo S.

Nat Genet. 2013 Sep;45(9):1004-12. doi: 10.1038/ng.2715. Epub 2013 Jul 28.

17.

miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.

Patel V, Williams D, Hajarnis S, Hunter R, Pontoglio M, Somlo S, Igarashi P.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10765-70. doi: 10.1073/pnas.1301693110. Epub 2013 Jun 12.

18.

Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β.

Choi YH, McNally BT, Igarashi P.

Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F100-10. doi: 10.1152/ajprenal.00582.2012. Epub 2013 May 8.

19.

Generation and characterization of KsprtTA and KsptTA transgenic mice.

Pan X, Small EV, Igarashi P, Carroll TJ.

Genesis. 2013 Jun;51(6):430-5. doi: 10.1002/dvg.22381. Epub 2013 Mar 28.

20.

Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis.

Shao X, Yang R, Yan M, Li Y, Du Y, Raman I, Zhang B, Wakeland EK, Igarashi P, Mohan C, Li QZ.

Arthritis Rheum. 2013 Mar;65(3):780-91. doi: 10.1002/art.37798. Erratum in: Arthritis Rheum. 2013 Apr;65(4):1106. Wakeland, Ward [corrected to Wakeland, Edward K].

Supplemental Content

Loading ...
Support Center