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Items: 1 to 20 of 97

1.

Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation.

Fujimori T, Suno R, Iemura SI, Natsume T, Wada I, Hosokawa N.

Genes Cells. 2017 Jun 9. doi: 10.1111/gtc.12506. [Epub ahead of print]

PMID:
28597544
2.

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

Kotani Y, Morito D, Sakata K, Ainuki S, Sugihara M, Hatta T, Iemura SI, Takashima S, Natsume T, Nagata K.

Sci Rep. 2017 Mar 9;7:44293. doi: 10.1038/srep44293.

3.

Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion.

Ohishi T, Yoshida H, Katori M, Migita T, Muramatsu Y, Miyake M, Ishikawa Y, Saiura A, Iemura SI, Natsume T, Seimiya H.

Cancer Res. 2017 May 1;77(9):2328-2338. doi: 10.1158/0008-5472.CAN-16-1846. Epub 2017 Feb 15.

PMID:
28202517
4.

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.

Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI.

Biochem Biophys Res Commun. 2017 Mar 11;484(3):522-528. doi: 10.1016/j.bbrc.2017.01.101. Epub 2017 Jan 23.

PMID:
28126338
5.

TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.

Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S.

J Biol Chem. 2017 Mar 10;292(10):4099-4112. doi: 10.1074/jbc.M116.769109. Epub 2017 Jan 23.

PMID:
28115518
6.

Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.

Ishida N, Nakagawa T, Iemura SI, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K.

Mol Cell Biol. 2017 Feb 1;37(4). pii: e00347-16. doi: 10.1128/MCB.00347-16. Print 2017 Feb 15.

PMID:
27895153
7.

WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway.

Goto T, Matsuzawa J, Iemura S, Natsume T, Shibuya H.

FEBS Lett. 2016 May;590(9):1291-303. doi: 10.1002/1873-3468.12180. Epub 2016 May 3.

8.

Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission.

Saita S, Ishihara T, Maeda M, Iemura S, Natsume T, Mihara K, Ishihara N.

Genes Cells. 2016 May;21(5):408-24. doi: 10.1111/gtc.12351. Epub 2016 Mar 3.

9.

Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi.

Fukuzono T, Pastuhov SI, Fukushima O, Li C, Hattori A, Iemura S, Natsume T, Shibuya H, Hanafusa H, Matsumoto K, Hisamoto N.

Genes Cells. 2016 Apr;21(4):311-24. doi: 10.1111/gtc.12338. Epub 2016 Feb 8.

10.

The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.

Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.

Sci Signal. 2015 Nov 24;8(404):ra120. doi: 10.1126/scisignal.aad0667.

PMID:
26602019
11.

TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress.

Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.

J Cell Biochem. 2016 Feb;117(2):500-9. doi: 10.1002/jcb.25301.

PMID:
26239904
12.

CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.

Kigoshi Y, Fukuda T, Endo T, Hayasaka N, Iemura S, Natsume T, Tsuruta F, Chiba T.

Sci Rep. 2015 Aug 4;5:12857. doi: 10.1038/srep12857.

13.

The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.

Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.

Biochem Biophys Res Commun. 2015 Jul 10;462(4):383-8. doi: 10.1016/j.bbrc.2015.04.144. Epub 2015 May 12.

PMID:
25976671
14.

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.

Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S.

Nat Commun. 2015 Apr 16;6:6780. doi: 10.1038/ncomms7780.

PMID:
25879670
15.

TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.

Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.

PLoS One. 2014 Nov 13;9(11):e112761. doi: 10.1371/journal.pone.0112761. eCollection 2014.

16.

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.

Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T.

Nucleic Acids Res. 2014 Sep;42(15):10037-49. doi: 10.1093/nar/gku652. Epub 2014 Aug 8.

17.

Structure-activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201.

Hayakawa N, Noguchi M, Takeshita S, Eviryanti A, Seki Y, Nishio H, Yokoyama R, Noguchi M, Shuto M, Shima Y, Kuribayashi K, Kageyama S, Eda H, Suzuki M, Hatta T, Iemura S, Natsume T, Tanabe I, Nakagawa R, Shiozaki M, Sakurai K, Shoji M, Andou A, Yamamoto T.

Bioorg Med Chem. 2014 Jun 1;22(11):3021-9. doi: 10.1016/j.bmc.2014.03.036. Epub 2014 Apr 13.

PMID:
24767819
18.

IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling.

Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H.

J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6.

19.

Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes.

Hoshi T, Tezuka T, Yokoyama K, Iemura S, Natsume T, Yamanashi Y.

FEBS Lett. 2013 Nov 29;587(23):3749-54. doi: 10.1016/j.febslet.2013.10.001. Epub 2013 Oct 15.

20.

Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases.

Araki K, Iemura S, Kamiya Y, Ron D, Kato K, Natsume T, Nagata K.

J Cell Biol. 2013 Sep 16;202(6):861-74. doi: 10.1083/jcb.201303027.

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