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Int J Qual Health Care. 2011 Apr;23(2):117-25. doi: 10.1093/intqhc/mzq087. Epub 2011 Jan 17.

Prevention of venous thromboembolism and safe use of heparin in Spanish hospitals.

Author information

1
Preventive Medicine and Public Health, University of Murcia, Murcia, Spain. psaturno@um.es

Abstract

OBJECTIVE:

To assess compliance with basic and actionable indicators in relation to prevention of venous thromboembolism (VTE) and safe use of heparin.

DESIGN:

We built, pilot tested and measured a set of evidence-based structure (existence of guidelines) and process (risk assessment for VTE, and dose adjustment to patient weight and renal function when prescribing heparin) indicators in a nation-wide random sample of 22 hospitals. Compliance with process indicators is estimated at national level and by groups of hospitals (stratified by size). At hospital level, compliance is assessed with Lot Quality Acceptance Sampling, for 85% compliance standard (α ≤ 0.05), 55% threshold (β ≤ 0.10). Contents of existing guidelines are analyzed, and their influence on performance is assessed using logistic regression.

SETTING:

Acute care hospitals in Spain.

INTERVENTIONS:

None

MAIN OUTCOME MEASURES:

Problem identification through indicators assessment.

RESULTS:

Less than half of hospitals have guidelines and their contents are very variable and incomplete. No hospital complies with the standard for VTE prevention and only one for heparin dose adjustment. Nationally, VTE risk assessment is performed in 5.8% of patients (95% CI: 5.6-6.0), and heparin dose is explicitly adjusted in 17.5% (95% CI: 16.8-18.2). Performance is relatively higher in large hospitals and it is associated with the existence of guidelines for VTE prevention (OR: 8.3; 95% CI: 2.1-32.1).

CONCLUSIONS:

We have identified some actionable contributing factors to safety problems using evidence-based structure and process indicators. Explicit process design and key clinical interventions (risk assessment for VTE and heparin dose adjustment) should be addressed to improve the current situation.

PMID:
21242163
DOI:
10.1093/intqhc/mzq087
[Indexed for MEDLINE]

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