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J Clin Oncol. 2006 Jul 10;24(20):3293-8.

Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker.

Author information

1
University of California, San Francisco, San Francisco, CA 94143-1290, USA. nola.hylton@radiology.ucsf.edu

Abstract

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is being used in oncology as a noninvasive method for measuring properties of the tumor microvasculature. There is potential for DCE-MRI to be used as an imaging biomarker to measure antiangiogenic effects of cancer treatments. This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials.

PMID:
16829653
DOI:
10.1200/JCO.2006.06.8080
[Indexed for MEDLINE]

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