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Items: 18

1.

Models of global gene expression define major domains of cell type and tissue identity.

Hutchins AP, Yang Z, Li Y, He F, Fu X, Wang X, Li D, Liu K, He J, Wang Y, Chen J, Esteban MA, Pei D.

Nucleic Acids Res. 2017 Mar 17;45(5):2354-2367. doi: 10.1093/nar/gkx054.

2.

Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.

Yang J, Wang Y, Zhou T, Wong LY, Tian XY, Hong X, Lai WH, Au KW, Wei R, Liu Y, Cheng LH, Liang G, Huang Z, Fan W, Zhao P, Wang X, Ibañez DP, Luo Z, Li Y, Zhong X, Chen S, Wang D, Li L, Lai L, Qin B, Bao X, Hutchins AP, Siu CW, Huang Y, Esteban MA, Tse HF.

Stem Cell Reports. 2017 Mar 14;8(3):605-618. doi: 10.1016/j.stemcr.2017.01.027. Epub 2017 Mar 2.

3.

Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis.

Huang K, Gao J, Du J, Ma N, Zhu Y, Wu P, Zhang T, Wang W, Li Y, Chen Q, Hutchins AP, Yang Z, Zheng Y, Zhang J, Shan Y, Li X, Liao B, Liu J, Wang J, Liu B, Pan G.

Stem Cell Reports. 2016 Nov 8;7(5):854-868. doi: 10.1016/j.stemcr.2016.09.008. Epub 2016 Oct 13.

4.

The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements.

Pugacheva EM, Teplyakov E, Wu Q, Li J, Chen C, Meng C, Liu J, Robinson S, Loukinov D, Boukaba A, Hutchins AP, Lobanenkov V, Strunnikov A.

Epigenetics Chromatin. 2016 Aug 31;9(1):35. doi: 10.1186/s13072-016-0084-2. eCollection 2016.

5.

Remission for Loss of Odontogenic Potential in a New Micromilieu In Vitro.

Zheng Y, Cai J, Hutchins AP, Jia L, Liu P, Yang D, Chen S, Ge L, Pei D, Wei S.

PLoS One. 2016 Apr 6;11(4):e0152893. doi: 10.1371/journal.pone.0152893. eCollection 2016.

6.

TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells.

Wang L, Li X, Huang W, Zhou T, Wang H, Lin A, Hutchins AP, Su Z, Chen Q, Pei D, Pan G.

Sci Rep. 2016 Mar 3;6:22484. doi: 10.1038/srep22484.

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The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters.

Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF, Pei D, Wang H, Zhang B, Esteban MA.

Cell Res. 2015 Jan;25(1):80-92. doi: 10.1038/cr.2014.165. Epub 2014 Dec 16.

10.

glbase: a framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data.

Hutchins AP, Jauch R, Dyla M, Miranda-Saavedra D.

Cell Regen (Lond). 2014 Jan 24;3(1):1. doi: 10.1186/2045-9769-3-1. eCollection 2014.

11.

Where cell fate conversions meet Chinese philosophy.

Zheng H, Hutchins AP, Pan G, Li Y, Pei D, Pei G.

Cell Res. 2014 Oct;24(10):1162-3. doi: 10.1038/cr.2014.93. Epub 2014 Jul 15.

12.

Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.

Hutchins AP, Diez D, Miranda-Saavedra D.

JAKSTAT. 2013 Oct 1;2(4):e25097. doi: 10.4161/jkst.25097. Epub 2013 May 20. Review.

13.

Systematic identification of transcriptional regulatory modules from protein-protein interaction networks.

Diez D, Hutchins AP, Miranda-Saavedra D.

Nucleic Acids Res. 2014 Jan;42(1):e6. doi: 10.1093/nar/gkt913. Epub 2013 Oct 16.

14.

The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges.

Hutchins AP, Diez D, Miranda-Saavedra D.

Brief Funct Genomics. 2013 Nov;12(6):489-98. doi: 10.1093/bfgp/elt028. Epub 2013 Aug 12. Review.

15.

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW.

EMBO J. 2013 Apr 3;32(7):938-53. doi: 10.1038/emboj.2013.31. Epub 2013 Mar 8.

16.

The repertoires of ubiquitinating and deubiquitinating enzymes in eukaryotic genomes.

Hutchins AP, Liu S, Diez D, Miranda-Saavedra D.

Mol Biol Evol. 2013 May;30(5):1172-87. doi: 10.1093/molbev/mst022. Epub 2013 Feb 7.

17.

Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling.

Clarke M, Lohan AJ, Liu B, Lagkouvardos I, Roy S, Zafar N, Bertelli C, Schilde C, Kianianmomeni A, Bürglin TR, Frech C, Turcotte B, Kopec KO, Synnott JM, Choo C, Paponov I, Finkler A, Heng Tan CS, Hutchins AP, Weinmeier T, Rattei T, Chu JS, Gimenez G, Irimia M, Rigden DJ, Fitzpatrick DA, Lorenzo-Morales J, Bateman A, Chiu CH, Tang P, Hegemann P, Fromm H, Raoult D, Greub G, Miranda-Saavedra D, Chen N, Nash P, Ginger ML, Horn M, Schaap P, Caler L, Loftus BJ.

Genome Biol. 2013 Feb 1;14(2):R11. doi: 10.1186/gb-2013-14-2-r11.

18.

Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.

Hutchins AP, Diez D, Takahashi Y, Ahmad S, Jauch R, Tremblay ML, Miranda-Saavedra D.

Nucleic Acids Res. 2013 Feb 1;41(4):2155-70. doi: 10.1093/nar/gks1300. Epub 2013 Jan 7.

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