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Items: 1 to 20 of 205

1.

Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry.

deVeber GA, Kirton A, Booth FA, Yager JY, Wirrell EC, Wood E, Shevell M, Surmava AM, McCusker P, Massicotte MP, MacGregor D, MacDonald EA, Meaney B, Levin S, Lemieux BG, Jardine L, Humphreys P, David M, Chan AK, Buckley DJ, Bjornson BH.

Pediatr Neurol. 2017 Apr;69:58-70. doi: 10.1016/j.pediatrneurol.2017.01.016. Epub 2017 Jan 26.

PMID:
28254555
2.

Floc Formation Reduces the pH Stress Experienced by Microorganisms Living in Alkaline Environments.

Charles CJ, Rout SP, Patel KA, Akbar S, Laws AP, Jackson BR, Boxall SA, Humphreys PN.

Appl Environ Microbiol. 2017 Mar 2;83(6). pii: e02985-16. doi: 10.1128/AEM.02985-16. Print 2017 Mar 15.

PMID:
28087527
3.

Draft Whole-Genome Sequence of the Alkaliphilic Alishewanella aestuarii Strain HH-ZS, Isolated from Historical Lime Kiln Waste-Contaminated Soil.

Salah ZB, Rout SP, Humphreys PN.

Genome Announc. 2016 Dec 29;4(6). pii: e01447-16. doi: 10.1128/genomeA.01447-16.

4.

Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe.

Humphreys PG, Bamborough P, Chung CW, Craggs PD, Gordon L, Grandi P, Hayhow TG, Hussain J, Jones KL, Lindon M, Michon AM, Renaux JF, Suckling CJ, Tough DF, Prinjha RK.

J Med Chem. 2017 Jan 26;60(2):695-709. doi: 10.1021/acs.jmedchem.6b01566. Epub 2017 Jan 9.

PMID:
28002667
5.

A Novel Rhamnose-Rich Hetero-exopolysaccharide Isolated from Lactobacillus paracasei DG Activates THP-1 Human Monocytic Cells.

Balzaretti S, Taverniti V, Guglielmetti S, Fiore W, Minuzzo M, Ngo HN, Ngere JB, Sadiq S, Humphreys PN, Laws AP.

Appl Environ Microbiol. 2017 Jan 17;83(3). pii: e02702-16. doi: 10.1128/AEM.02702-16. Print 2017 Feb 1.

PMID:
27913418
6.

Microbial Community Evolution Is Significantly Impacted by the Use of Calcium Isosaccharinic Acid as an Analogue for the Products of Alkaline Cellulose Degradation.

Kyeremeh IA, Charles CJ, Rout SP, Laws AP, Humphreys PN.

PLoS One. 2016 Nov 2;11(11):e0165832. doi: 10.1371/journal.pone.0165832. eCollection 2016 Nov 2.

7.

Activity and MeCP2-dependent regulation of nNOS levels in enteric neurons.

Wahba G, Schock SC, Cudd S, Grynspan D, Humphreys P, Staines WA.

Neurogastroenterol Motil. 2016 Nov;28(11):1723-1730. doi: 10.1111/nmo.12873. Epub 2016 Jun 2.

PMID:
27254746
8.

Quantum memories: emerging applications and recent advances.

Heshami K, England DG, Humphreys PC, Bustard PJ, Acosta VM, Nunn J, Sussman BJ.

J Mod Opt. 2016 Nov 12;63(20):2005-2028. Epub 2016 Mar 16. Review.

9.

Viability of Lucilia sericata maggots after exposure to wound antiseptics.

Daeschlein G, Napp M, Assadian O, von Podewils S, Reese K, Hinz P, Matiasek J, Spitzmueller R, Humphreys P, Jünger M, Kramer A.

Int Wound J. 2016 Jul 11. doi: 10.1111/iwj.12637. [Epub ahead of print]

PMID:
27396987
10.

Evolution of an audit and monitoring tool into an infection prevention and control process.

Denton A, Topping A, Humphreys P.

J Hosp Infect. 2016 Sep;94(1):32-40. doi: 10.1016/j.jhin.2016.04.017. Epub 2016 May 12.

PMID:
27313140
11.

Clinical progress and pharmacology of small molecule bromodomain inhibitors.

Theodoulou NH, Tomkinson NC, Prinjha RK, Humphreys PG.

Curr Opin Chem Biol. 2016 Aug;33:58-66. doi: 10.1016/j.cbpa.2016.05.028. Epub 2016 Jun 10. Review.

PMID:
27295577
12.

Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics.

Joberty G, Boesche M, Brown JA, Eberhard D, Garton NS, Humphreys PG, Mathieson T, Muelbaier M, Ramsden NG, Reader V, Rueger A, Sheppard RJ, Westaway SM, Bantscheff M, Lee K, Wilson DM, Prinjha RK, Drewes G.

ACS Chem Biol. 2016 Jul 15;11(7):2002-10. doi: 10.1021/acschembio.6b00080. Epub 2016 May 19.

PMID:
27197014
13.
14.

The Incidence and Evolution of Parkinsonian Rigidity in Rett Syndrome: A Pilot Study.

Humphreys P, Barrowman N.

Can J Neurol Sci. 2016 Jul;43(4):567-73. doi: 10.1017/cjn.2016.8. Epub 2016 Apr 6.

PMID:
27050783
15.

Clinical Guidelines for Management of Bone Health in Rett Syndrome Based on Expert Consensus and Available Evidence.

Jefferson A, Leonard H, Siafarikas A, Woodhead H, Fyfe S, Ward LM, Munns C, Motil K, Tarquinio D, Shapiro JR, Brismar T, Ben-Zeev B, Bisgaard AM, Coppola G, Ellaway C, Freilinger M, Geerts S, Humphreys P, Jones M, Lane J, Larsson G, Lotan M, Percy A, Pineda M, Skinner S, Syhler B, Thompson S, Weiss B, Witt Engerström I, Downs J.

PLoS One. 2016 Feb 5;11(2):e0146824. doi: 10.1371/journal.pone.0146824. eCollection 2016 Feb 5.

16.

Isolation of sophorose during sophorolipid production and studies of its stability in aqueous alkali: epimerisation of sophorose to 2-O-β-D-glucopyranosyl-D-mannose.

Al-Jasim A, Davis M, Cossar D, Miller T, Humphreys P, Laws AP.

Carbohydr Res. 2016 Feb 8;421:46-54. doi: 10.1016/j.carres.2015.12.001. Epub 2016 Jan 7.

PMID:
26774878
17.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Drewes G, Eagle R, Garton N, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Pemberton M, Rioja I, Seal GA, Shipley T, Singh O, Suckling CJ, Taylor J, Thomas P, Wilson DM, Lee K, Prinjha RK.

J Med Chem. 2016 Feb 25;59(4):1370-87. doi: 10.1021/acs.jmedchem.5b01538. Epub 2016 Jan 15.

PMID:
26771203
18.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Diallo H, Douault C, Drewes G, Eagle R, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Liddle J, Mosley J, Muelbaier M, Randle R, Rioja I, Rueger A, Seal GA, Sheppard RJ, Singh O, Taylor J, Thomas P, Thomson D, Wilson DM, Lee K, Prinjha RK.

J Med Chem. 2016 Feb 25;59(4):1357-69. doi: 10.1021/acs.jmedchem.5b01537. Epub 2016 Jan 15.

PMID:
26771107
19.

Progress in the Development of non-BET Bromodomain Chemical Probes.

Theodoulou NH, Tomkinson NC, Prinjha RK, Humphreys PG.

ChemMedChem. 2016 Mar 4;11(5):477-87. doi: 10.1002/cmdc.201500540. Epub 2016 Jan 8. Review.

PMID:
26749027
20.

What are the reasons for improved survival following spine fusion for severe scoliosis in Rett syndrome?

Humphreys P.

Dev Med Child Neurol. 2016 Jun;58(6):538-9. doi: 10.1111/dmcn.12993. Epub 2015 Dec 11. No abstract available.

PMID:
26661711

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