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Items: 1 to 20 of 279

1.

Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies.

Klein RD, Hultgren SJ.

Nat Rev Microbiol. 2020 Feb 18. doi: 10.1038/s41579-020-0324-0. [Epub ahead of print] Review.

PMID:
32071440
2.

High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration.

Walker JN, Flores-Mireles AL, Lynch AJL, Pinkner C, Caparon MG, Hultgren SJ, Desai A.

World J Urol. 2019 Dec 2. doi: 10.1007/s00345-019-03027-8. [Epub ahead of print]

PMID:
31792577
3.

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence.

Yu L, O'Brien VP, Livny J, Dorsey D, Bandyopadhyay N, Colonna M, Caparon MG, Roberson ED, Hultgren SJ, Hannan TJ.

Elife. 2019 Aug 20;8. pii: e46677. doi: 10.7554/eLife.46677.

4.

(p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection.

Colomer-Winter C, Flores-Mireles AL, Kundra S, Hultgren SJ, Lemos JA.

mSphere. 2019 Jul 24;4(4). pii: e00392-19. doi: 10.1128/mSphere.00392-19.

5.

Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma.

Walker JN, Hanson BM, Pinkner CL, Simar SR, Pinkner JS, Parikh R, Clemens MW, Hultgren SJ, Myckatyn TM.

Sci Rep. 2019 Jul 17;9(1):10393. doi: 10.1038/s41598-019-46535-8.

6.

Establishment and Characterization of Bacterial Infection of Breast Implants in a Murine Model.

Walker JN, Poppler L, Pinkner CL, Hultgren SJ, Myckatyn T.

Aesthet Surg J. 2019 Jul 1. pii: sjz190. doi: 10.1093/asj/sjz190. [Epub ahead of print]

PMID:
31259380
7.

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes.

Di Venanzio G, Flores-Mireles AL, Calix JJ, Haurat MF, Scott NE, Palmer LD, Potter RF, Hibbing ME, Friedman L, Wang B, Dantas G, Skaar EP, Hultgren SJ, Feldman MF.

Nat Commun. 2019 Jun 24;10(1):2763. doi: 10.1038/s41467-019-10706-y.

8.

Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae.

Ambite I, Butler DSC, Stork C, Grönberg-Hernández J, Köves B, Zdziarski J, Pinkner J, Hultgren SJ, Dobrindt U, Wullt B, Svanborg C.

PLoS Pathog. 2019 Jun 10;15(6):e1007671. doi: 10.1371/journal.ppat.1007671. eCollection 2019 Jun.

9.

Reaching the End of the Line: Urinary Tract Infections.

Tamadonfar KO, Omattage NS, Spaulding CN, Hultgren SJ.

Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0014-2019.

PMID:
31172909
10.

Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.

Flentie K, Harrison GA, Tükenmez H, Livny J, Good JAD, Sarkar S, Zhu DX, Kinsella RL, Weiss LA, Solomon SD, Schene ME, Hansen MR, Cairns AG, Kulén M, Wixe T, Lindgren AEG, Chorell E, Bengtsson C, Krishnan KS, Hultgren SJ, Larsson C, Almqvist F, Stallings CL.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10510-10517. doi: 10.1073/pnas.1818009116. Epub 2019 May 6.

11.

Deposition of Host Matrix Proteins on Breast Implant Surfaces Facilitates Staphylococcus Epidermidis Biofilm Formation: In Vitro Analysis.

Walker JN, Pinkner CL, Lynch AJL, Ortbal S, Pinkner JS, Hultgren SJ, Myckatyn TM.

Aesthet Surg J. 2020 Feb 17;40(3):281-295. doi: 10.1093/asj/sjz099.

PMID:
30953053
12.

The Detection of Bacteria and Matrix Proteins on Clinically Benign and Pathologic Implants.

Walker JN, Pinkner CL, Pinkner JS, Hultgren SJ, Myckatyn TM.

Plast Reconstr Surg Glob Open. 2019 Feb 8;7(2):e2037. doi: 10.1097/GOX.0000000000002037. eCollection 2019 Feb.

13.

Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner.

O'Brien VP, Dorsey DA, Hannan TJ, Hultgren SJ.

PLoS Pathog. 2018 Dec 13;14(12):e1007457. doi: 10.1371/journal.ppat.1007457. eCollection 2018 Dec.

14.

Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design.

Maddirala AR, Klein R, Pinkner JS, Kalas V, Hultgren SJ, Janetka JW.

J Med Chem. 2019 Jan 24;62(2):467-479. doi: 10.1021/acs.jmedchem.8b01561. Epub 2019 Jan 2.

15.

Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.

Omattage NS, Deng Z, Pinkner JS, Dodson KW, Almqvist F, Yuan P, Hultgren SJ.

Nat Microbiol. 2018 Dec;3(12):1362-1368. doi: 10.1038/s41564-018-0255-y. Epub 2018 Oct 1.

16.

Manganese acquisition is essential for virulence of Enterococcus faecalis.

Colomer-Winter C, Flores-Mireles AL, Baker SP, Frank KL, Lynch AJL, Hultgren SJ, Kitten T, Lemos JA.

PLoS Pathog. 2018 Sep 20;14(9):e1007102. doi: 10.1371/journal.ppat.1007102. eCollection 2018 Sep.

17.

Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation.

Klein RD, Shu Q, Cusumano ZT, Nagamatsu K, Gualberto NC, Lynch AJL, Wu C, Wang W, Jain N, Pinkner JS, Amarasinghe GK, Hultgren SJ, Frieden C, Chapman MR.

mBio. 2018 Jul 17;9(4). pii: e01349-18. doi: 10.1128/mBio.01349-18.

18.

Differential Regulation of Escherichia coli fim Genes following Binding to Mannose Receptors.

Schwan WR, Beck MT, Hung CS, Hultgren SJ.

J Pathog. 2018 May 22;2018:2897581. doi: 10.1155/2018/2897581. eCollection 2018.

19.

Hydrogen Sulfide Sensing through Reactive Sulfur Species (RSS) and Nitroxyl (HNO) in Enterococcus faecalis.

Shen J, Walsh BJC, Flores-Mireles AL, Peng H, Zhang Y, Zhang Y, Trinidad JC, Hultgren SJ, Giedroc DP.

ACS Chem Biol. 2018 Jun 15;13(6):1610-1620. doi: 10.1021/acschembio.8b00230. Epub 2018 May 17.

20.

Precision antimicrobial therapeutics: the path of least resistance?

Spaulding CN, Klein RD, Schreiber HL 4th, Janetka JW, Hultgren SJ.

NPJ Biofilms Microbiomes. 2018 Feb 27;4:4. doi: 10.1038/s41522-018-0048-3. eCollection 2018. Review.

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