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3D microtumors in vitro supported by perfused vascular networks.

Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC.

Sci Rep. 2016 Aug 23;6:31589. doi: 10.1038/srep31589.


Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Fong AH, Romero-López M, Heylman CM, Keating M, Tran D, Sobrino A, Tran AQ, Pham HH, Fimbres C, Gershon PD, Botvinick EL, George SC, Hughes CC.

Tissue Eng Part A. 2016 Aug;22(15-16):1016-25. doi: 10.1089/ten.TEA.2016.0027.


New Curculionoidea records from New Brunswick, Canada with an addition to the fauna of Nova Scotia.

Webster RP, Anderson RS, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):367-86. doi: 10.3897/zookeys.573.7444. eCollection 2016.


The Ciidae (Coleoptera) of New Brunswick, Canada: New records and new synonyms.

Lopes-Andrade C, Webster RP, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):339-66. doi: 10.3897/zookeys.573.7445. eCollection 2016.


Further contributions to the Coleoptera fauna of New Brunswick with an addition to the fauna of Nova Scotia, Canada.

Webster RP, Webster VL, Alderson CA, Hughes CC, Sweeney JD.

Zookeys. 2016 Mar 24;(573):265-338. doi: 10.3897/zookeys.573.7327. eCollection 2016.


Further contributions to the Aleocharinae (Coleoptera, Staphylinidae) fauna of New Brunswick and Canada including descriptions of 27 new species.

Webster RP, Klimaszewski J, Bourdon C, Sweeney JD, Hughes CC, Labrecque M.

Zookeys. 2016 Mar 24;(573):85-216. doi: 10.3897/zookeys.573.7016. eCollection 2016.


mTORC2 mediates CXCL12-induced angiogenesis.

Ziegler ME, Hatch MM, Wu N, Muawad SA, Hughes CC.

Angiogenesis. 2016 Jul;19(3):359-71. doi: 10.1007/s10456-016-9509-6. Epub 2016 Apr 22.


An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms.

Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP.

Lab Chip. 2016 Mar 7;16(5):868-876. doi: 10.1039/c5lc01563d.


Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.

Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP.

Lab Chip. 2016 Jan 21;16(2):282-90. doi: 10.1039/c5lc01050k.


A role for partial endothelial-mesenchymal transitions in angiogenesis?

Welch-Reardon KM, Wu N, Hughes CC.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):303-8. doi: 10.1161/ATVBAHA.114.303220. Epub 2014 Nov 25. Review.


Sioxanthin, a novel glycosylated carotenoid, reveals an unusual subclustered biosynthetic pathway.

Richter TK, Hughes CC, Moore BS.

Environ Microbiol. 2015 Jun;17(6):2158-71. doi: 10.1111/1462-2920.12669. Epub 2014 Dec 11.


A three-dimensional in vitro model of tumor cell intravasation.

Ehsan SM, Welch-Reardon KM, Waterman ML, Hughes CC, George SC.

Integr Biol (Camb). 2014 Jun;6(6):603-10. doi: 10.1039/c3ib40170g.


A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.

Heylman C, Sobrino A, Shirure VS, Hughes CC, George SC.

Exp Biol Med (Maywood). 2014 Sep;239(9):1240-54. doi: 10.1177/1535370214525295. Epub 2014 Apr 16. Review.


Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis.

Popson SA, Ziegler ME, Chen X, Holderfield MT, Shaaban CI, Fong AH, Welch-Reardon KM, Papkoff J, Hughes CC.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1011-9. doi: 10.1161/ATVBAHA.114.303352. Epub 2014 Mar 6.


Implanted cell-dense prevascularized tissues develop functional vasculature that supports reoxygenation after thrombosis.

White SM, Pittman CR, Hingorani R, Arora R, Esipova TV, Vinogradov SA, Hughes CC, Choi B, George SC.

Tissue Eng Part A. 2014 Sep;20(17-18):2316-28. doi: 10.1089/ten.TEA.2013.0311. Epub 2014 Jun 30.


Angiogenic sprouting is regulated by endothelial cell expression of Slug.

Welch-Reardon KM, Ehsan SM, Wang K, Wu N, Newman AC, Romero-Lopez M, Fong AH, George SC, Edwards RA, Hughes CC.

J Cell Sci. 2014 May 1;127(Pt 9):2017-28. doi: 10.1242/jcs.143420. Epub 2014 Feb 19.


A screen for short-range paracrine interactions.

Spencer KH, Kim MY, Hughes CC, Hui EE.

Integr Biol (Camb). 2014 Apr;6(4):382-7. doi: 10.1039/c3ib40211h. Epub 2014 Feb 13.


Purported Mcl-1 inhibitor marinopyrrole A fails to show selective cytotoxicity for Mcl-1-dependent cell lines.

Eichhorn JM, Alford SE, Hughes CC, Fenical W, Chambers TC.

Cell Death Dis. 2013 Oct 24;4:e880. doi: 10.1038/cddis.2013.411. No abstract available.


A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays.

Hsu YH, Moya ML, Hughes CC, George SC, Lee AP.

Lab Chip. 2013 Aug 7;13(15):2990-8. doi: 10.1039/c3lc50424g.

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