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Logistical challenges and design considerations for studies using acute anterior cruciate ligament injury as a potential model for early posttraumatic osteoarthritis.

Lattermann C, Jacobs CA, Bunnell MP, Jochimsen KN, Abt JP, Reinke EK, Gammon LG, Huebner JL, Kraus VB, Spindler KP.

J Orthop Res. 2016 Jun 9. doi: 10.1002/jor.23329. [Epub ahead of print]


Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation.

Huebner JL, Landerman LR, Somers TJ, Keefe FJ, Guilak F, Blumenthal JA, Caldwell DS, Kraus VB.

Osteoarthritis Cartilage. 2016 Sep;24(9):1528-34. doi: 10.1016/j.joca.2016.04.002. Epub 2016 Apr 16.


Direct in vivo evidence of activated macrophages in human osteoarthritis.

Kraus VB, McDaniel G, Huebner JL, Stabler TV, Pieper CF, Shipes SW, Petry NA, Low PS, Shen J, McNearney TA, Mitchell P.

Osteoarthritis Cartilage. 2016 Sep;24(9):1613-21. doi: 10.1016/j.joca.2016.04.010. Epub 2016 Apr 12.


Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al.

Olson SA, Furman BD, Kraus VB, Huebner JL, Guilak F.

J Orthop Res. 2016 Jan;34(1):15-6. doi: 10.1002/jor.23095. Epub 2015 Dec 8. No abstract available.


Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats.

Fu Y, Huebner JL, Kraus VB, Griffin TM.

J Gerontol A Biol Sci Med Sci. 2016 Sep;71(9):1131-40. doi: 10.1093/gerona/glv151. Epub 2015 Oct 8.


Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture.

Adams SB, Setton LA, Bell RD, Easley ME, Huebner JL, Stabler T, Kraus VB, Leimer EM, Olson SA, Nettles DL.

Foot Ankle Int. 2015 Nov;36(11):1264-71. doi: 10.1177/1071100715611176. Epub 2015 Oct 8.


In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy.

Bowles RD, Karikari IO, VanDerwerken DN, Sinclair MS, Bell RD, Riebe KJ, Huebner JL, Kraus VB, Sempowski GD, Setton LA.

Eur J Pain. 2016 Mar;20(3):365-76. doi: 10.1002/ejp.732. Epub 2015 May 29.


Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.

Olson SA, Furman BD, Kraus VB, Huebner JL, Guilak F.

J Orthop Res. 2015 Sep;33(9):1266-77. doi: 10.1002/jor.22940. Epub 2015 Jun 7.


Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines.

Furman BD, Kimmerling KA, Zura RD, Reilly RM, Zlowodzki MP, Huebner JL, Kraus VB, Guilak F, Olson SA.

Arthritis Rheumatol. 2015 May;67(5):1234-9. doi: 10.1002/art.39064.


Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.

Kimmerling KA, Furman BD, Mangiapani DS, Moverman MA, Sinclair SM, Huebner JL, Chilkoti A, Kraus VB, Setton LA, Guilak F, Olson SA.

Eur Cell Mater. 2015 Jan 31;29:124-39; discussion 139-40.


A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls.

Bartlett DB, Connelly MA, AbouAssi H, Bateman LA, Tune KN, Huebner JL, Kraus VB, Winegar DA, Otvos JD, Kraus WE, Huffman KM.

Arthritis Res Ther. 2016 Apr 12;18:86. doi: 10.1186/s13075-016-0982-5.


Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury.

Wu CL, Jain D, McNeill JN, Little D, Anderson JA, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Guilak F.

Ann Rheum Dis. 2015 Nov;74(11):2076-83. doi: 10.1136/annrheumdis-2014-205601. Epub 2014 Jul 10.


Adipose depots, not disease-related factors, account for skeletal muscle insulin sensitivity in established and treated rheumatoid arthritis.

AbouAssi H, Tune KN, Gilmore B, Bateman LA, McDaniel G, Muehlbauer M, Huebner JL, Hoenig HM, Kraus VB, St Clair EW, Kraus WE, Huffman KM.

J Rheumatol. 2014 Oct;41(10):1974-9. doi: 10.3899/jrheum.140224. Epub 2014 Jul 1.


Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.

Furman BD, Mangiapani DS, Zeitler E, Bailey KN, Horne PH, Huebner JL, Kraus VB, Guilak F, Olson SA.

Arthritis Res Ther. 2014 Jun 25;16(3):R134. doi: 10.1186/ar4591.


Alpha C-telopeptide of type I collagen is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis.

Huebner JL, Bay-Jensen AC, Huffman KM, He Y, Leeming DJ, McDaniel GE, Karsdal MA, Kraus VB.

Arthritis Rheumatol. 2014 Sep;66(9):2440-9. doi: 10.1002/art.38739.


In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis.

Bowles RD, Mata BA, Bell RD, Mwangi TK, Huebner JL, Kraus VB, Setton LA.

Arthritis Rheumatol. 2014 Mar;66(3):637-46. doi: 10.1002/art.38279.


Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: results from a randomized controlled pilot study.

Hunt MA, Pollock CL, Kraus VB, Saxne T, Peters S, Huebner JL, Sayre EC, Cibere J.

BMC Musculoskelet Disord. 2013 Mar 27;14:115. doi: 10.1186/1471-2474-14-115.


Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.

Lewis JS Jr, Furman BD, Zeitler E, Huebner JL, Kraus VB, Guilak F, Olson SA.

Arthritis Rheum. 2013 Mar;65(3):660-70. doi: 10.1002/art.37796.


Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy.

Hwang PY, Allen KD, Shamji MF, Jing L, Mata BA, Gabr MA, Huebner JL, Kraus VB, Richardson WJ, Setton LA.

Open Orthop J. 2012;6:383-91. doi: 10.2174/1874325001206010383. Epub 2012 Sep 3.


Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis.

Diekman BO, Wu CL, Louer CR, Furman BD, Huebner JL, Kraus VB, Olson SA, Guilak F.

Cell Transplant. 2013;22(8):1395-408. doi: 10.3727/096368912X653264. Epub 2012 Aug 10.

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