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Items: 13

1.

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology.

Bakeer N, James J, Roy S, Wansapura J, Shanmukhappa SK, Lorenz JN, Osinska H, Backer K, Huby AC, Shrestha A, Niss O, Fleck R, Quinn CT, Taylor MD, Purevjav E, Aronow BJ, Towbin JA, Malik P.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5182-91. doi: 10.1073/pnas.1600311113. Epub 2016 Aug 8.

2.

Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice.

Huby AC, Otvos L Jr, Belin de Chantemèle EJ.

Hypertension. 2016 May;67(5):1020-8. doi: 10.1161/HYPERTENSIONAHA.115.06642. Epub 2016 Mar 7.

3.

FasL expression in cardiomyocytes activates the ERK1/2 pathway, leading to dilated cardiomyopathy and advanced heart failure.

Huby AC, Turdi S, James J, Towbin JA, Purevjav E.

Clin Sci (Lond). 2016 Feb;130(4):289-99. doi: 10.1042/CS20150624. Epub 2015 Nov 13.

PMID:
26566650
4.

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis.

Huby AC, Antonova G, Groenendyk J, Gomez-Sanchez CE, Bollag WB, Filosa JA, Belin de Chantemèle EJ.

Circulation. 2015 Dec 1;132(22):2134-45. doi: 10.1161/CIRCULATIONAHA.115.018226. Epub 2015 Sep 11.

PMID:
26362633
5.

Reviving the use of aldosterone inhibitors in treating hypertension in obesity.

Huby AC, Belin De Chantemèle EJ.

Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1065-7. doi: 10.1152/ajpregu.00133.2015. Epub 2015 Jul 8. Review.

6.

Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction.

Herren DJ, Norman JB, Anderson R, Tremblay ML, Huby AC, Belin de Chantemèle EJ.

PLoS One. 2015 May 14;10(5):e0126866. doi: 10.1371/journal.pone.0126866. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0130781. Herre, David J [corrected to Herren, David J].

7.

Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy.

Huby AC, Mendsaikhan U, Takagi K, Martherus R, Wansapura J, Gong N, Osinska H, James JF, Kramer K, Saito K, Robbins J, Khuchua Z, Towbin JA, Purevjav E.

J Am Coll Cardiol. 2014 Dec 30;64(25):2765-76. doi: 10.1016/j.jacc.2014.09.071.

8.

The RenTg mice: a powerful tool to study renin-dependent chronic kidney disease.

Huby AC, Kavvadas P, Alfieri C, Abed A, Toubas J, Rastaldi MP, Dussaule JC, Chatziantoniou C, Chadjichristos CE.

PLoS One. 2012;7(12):e52362. doi: 10.1371/journal.pone.0052362. Epub 2012 Dec 26.

9.

Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations.

Purevjav E, Arimura T, Augustin S, Huby AC, Takagi K, Nunoda S, Kearney DL, Taylor MD, Terasaki F, Bos JM, Ommen SR, Shibata H, Takahashi M, Itoh-Satoh M, McKenna WJ, Murphy RT, Labeit S, Yamanaka Y, Machida N, Park JE, Alexander PM, Weintraub RG, Kitaura Y, Ackerman MJ, Kimura A, Towbin JA.

Hum Mol Genet. 2012 May 1;21(9):2039-53. doi: 10.1093/hmg/dds022. Epub 2012 Jan 27.

10.

Alteration of connexin expression is an early signal for chronic kidney disease.

Toubas J, Beck S, Pageaud AL, Huby AC, Mael-Ainin M, Dussaule JC, Chatziantoniou C, Chadjichristos CE.

Am J Physiol Renal Physiol. 2011 Jul;301(1):F24-32. doi: 10.1152/ajprenal.00255.2010. Epub 2011 Mar 23.

11.

The role of cell plasticity in progression and reversal of renal fibrosis.

Dussaule JC, Guerrot D, Huby AC, Chadjichristos C, Shweke N, Boffa JJ, Chatziantoniou C.

Int J Exp Pathol. 2011 Jun;92(3):151-7. doi: 10.1111/j.1365-2613.2011.00760.x. Epub 2011 Feb 12. Review.

12.

[Role of cell plasticity in progression and regression of renal fibrosis].

Dussaule JC, Guerrot D, Huby AC, Boffa JJ, Chatziantoniou C.

Bull Acad Natl Med. 2009 Dec;193(9):1993-2003; discussion 2003-4. French.

PMID:
20666013
13.

Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.

Huby AC, Rastaldi MP, Caron K, Smithies O, Dussaule JC, Chatziantoniou C.

PLoS One. 2009 Aug 21;4(8):e6721. doi: 10.1371/journal.pone.0006721.

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