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Items: 1 to 20 of 199

1.

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT.

Elife. 2017 Oct 31;6. pii: e26116. doi: 10.7554/eLife.26116. [Epub ahead of print]

2.

Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons.

Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, Chang HY.

Cell Rep. 2017 Sep 26;20(13):3236-3247. doi: 10.1016/j.celrep.2017.09.011.

3.

Mechanistic insights in X-chromosome inactivation.

Lu Z, Carter AC, Chang HY.

Philos Trans R Soc Lond B Biol Sci. 2017 Nov 5;372(1733). pii: 20160356. doi: 10.1098/rstb.2016.0356. Review.

PMID:
28947655
4.

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY.

Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25.

PMID:
28945252
5.

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30.

6.

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, Orloff LA, Risca VI, Kundaje A, Khavari PA, Montine TJ, Greenleaf WJ, Chang HY.

Nat Methods. 2017 Oct;14(10):959-962. doi: 10.1038/nmeth.4396. Epub 2017 Aug 28.

7.

Gene regulation in the immune system by long noncoding RNAs.

Chen YG, Satpathy AT, Chang HY.

Nat Immunol. 2017 Aug 22;18(9):962-972. doi: 10.1038/ni.3771. Review.

PMID:
28829444
8.

Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.

Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, Snyder M, Chang HY, Fraser P, Khavari PA.

Nat Genet. 2017 Oct;49(10):1522-1528. doi: 10.1038/ng.3935. Epub 2017 Aug 14.

PMID:
28805829
9.

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.

Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA.

Nature. 2017 Aug 17;548(7667):338-342. doi: 10.1038/nature23450. Epub 2017 Aug 9.

PMID:
28792938
10.

IL-4Rα Inhibitor for Atopic Disease.

Chang HY, Nadeau KC.

Cell. 2017 Jul 13;170(2):222. doi: 10.1016/j.cell.2017.06.046.

PMID:
28708993
11.

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs.

Liu Q, Jiang C, Xu J, Zhao MT, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP.

Circ Res. 2017 Aug 4;121(4):376-391. doi: 10.1161/CIRCRESAHA.116.310456. Epub 2017 Jun 29.

PMID:
28663367
12.

Transcription coactivator and lncRNA duet evoke Hox genes.

Wang KC, Chang HY.

PLoS Genet. 2017 Jun 29;13(6):e1006797. doi: 10.1371/journal.pgen.1006797. eCollection 2017 Jun. No abstract available.

13.

Sensing Self and Foreign Circular RNAs by Intron Identity.

Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY.

Mol Cell. 2017 Jul 20;67(2):228-238.e5. doi: 10.1016/j.molcel.2017.05.022. Epub 2017 Jun 15.

14.

Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors.

Qu K, Zaba LC, Satpathy AT, Giresi PG, Li R, Jin Y, Armstrong R, Jin C, Schmitt N, Rahbar Z, Ueno H, Greenleaf WJ, Kim YH, Chang HY.

Cancer Cell. 2017 Jul 10;32(1):27-41.e4. doi: 10.1016/j.ccell.2017.05.008. Epub 2017 Jun 15.

PMID:
28625481
15.

The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.

Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M.

Cell. 2017 Jun 1;169(6):1051-1065.e18. doi: 10.1016/j.cell.2017.05.022.

PMID:
28575669
16.

Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY.

Nat Genet. 2017 May 26;49(6):970. doi: 10.1038/ng0617-970a. No abstract available.

PMID:
28546577
17.

Generation of pure GABAergic neurons by transcription factor programming.

Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, Buylla AA, Südhof TC, Wernig M.

Nat Methods. 2017 Jun;14(6):621-628. doi: 10.1038/nmeth.4291. Epub 2017 May 15.

18.

Two-Stage Explantation of a Magnetic Lower Esophageal Sphincter Augmentation Device Due to Esophageal Erosion.

Parmar AD, Tessler RA, Chang HY, Svahn JD.

J Laparoendosc Adv Surg Tech A. 2017 Aug;27(8):829-833. doi: 10.1089/lap.2017.0153. Epub 2017 May 10.

PMID:
28488920
19.

Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.

Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ.

Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13.

20.

Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology.

Schmitt AM, Chang HY.

Cold Spring Harb Perspect Med. 2017 Jul 5;7(7). pii: a026492. doi: 10.1101/cshperspect.a026492. Review.

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