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Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model.

Hao J, Tuck AR, Sjödin MOD, Lindberg J, Sand A, Niklasson B, Argyraki M, Hovatta O, Damdimopoulou P.

Toxicol Appl Pharmacol. 2018 Jan 1;338:73-82. doi: 10.1016/j.taap.2017.11.009. Epub 2017 Nov 14.


Phenotypic Screen Identifies a Small Molecule Modulating ERK2 and Promoting Stem Cell Proliferation.

Yin C, Fufa T, Chandrasekar G, Aeluri M, Zaky V, Abdelhady S, Rodríguez AB, Jakobsson J, Varnoosfaderani FS, Mahalingam J, Liu J, Larsson O, Hovatta O, Gaunitz F, Göndör A, Andäng M, Kitambi SS.

Front Pharmacol. 2017 Oct 24;8:726. doi: 10.3389/fphar.2017.00726. eCollection 2017.


A missense mutation in SLC26A3 is associated with human male subfertility and impaired activation of CFTR.

Wedenoja S, Khamaysi A, Shimshilashvili L, Anbtawe-Jomaa S, Elomaa O, Toppari J, Höglund P, Aittomäki K, Holmberg C, Hovatta O, Tapanainen JS, Ohana E, Kere J.

Sci Rep. 2017 Oct 27;7(1):14208. doi: 10.1038/s41598-017-14606-3.


Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting.

Gravholt CH, Andersen NH, Conway GS, Dekkers OM, Geffner ME, Klein KO, Lin AE, Mauras N, Quigley CA, Rubin K, Sandberg DE, Sas TCJ, Silberbach M, Söderström-Anttila V, Stochholm K, van Alfen-van derVelden JA, Woelfle J, Backeljauw PF; International Turner Syndrome Consensus Group.

Eur J Endocrinol. 2017 Sep;177(3):G1-G70. doi: 10.1530/EJE-17-0430. Review.


RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells.

Lund RJ, Rahkonen N, Malonzo M, Kauko L, Emani MR, Kivinen V, Närvä E, Kemppainen E, Laiho A, Skottman H, Hovatta O, Rasool O, Nykter M, Lähdesmäki H, Lahesmaa R.

Stem Cell Reports. 2017 May 9;8(5):1442-1454. doi: 10.1016/j.stemcr.2017.04.016.


Quality Assurance in Stem Cell Banking: Emphasis on Embryonic and Induced Pluripotent Stem Cell Banking.

Kallur T, Blomberg P, Stenfelt S, Tryggvason K, Hovatta O.

Methods Mol Biol. 2017;1590:11-16. doi: 10.1007/978-1-4939-6921-0_2.


Expression of Pluripotency Markers in Nonpluripotent Human Neural Stem and Progenitor Cells.

Vincent PH, Benedikz E, Uhlén P, Hovatta O, Sundström E.

Stem Cells Dev. 2017 Jun 15;26(12):876-887. doi: 10.1089/scd.2016.0346. Epub 2017 Mar 27.


Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells.

Panula S, Reda A, Stukenborg JB, Ramathal C, Sukhwani M, Albalushi H, Edsgärd D, Nakamura M, Söder O, Orwig KE, Yamanaka S, Reijo Pera RA, Hovatta O.

PLoS One. 2016 Oct 21;11(10):e0165268. doi: 10.1371/journal.pone.0165268. eCollection 2016.


Who benefits from putting family life into ice?

Hovatta O.

Ups J Med Sci. 2016 Oct 19:1-3. [Epub ahead of print] No abstract available.


Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems.

Nguyen MTX, Okina E, Chai X, Tan KH, Hovatta O, Ghosh S, Tryggvason K.

Stem Cell Reports. 2016 Oct 11;7(4):802-816. doi: 10.1016/j.stemcr.2016.08.017. Epub 2016 Sep 29.


Corrigendum: Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos.

Madissoon E, Jouhilahti EM, Vesterlund L, Töhönen V, Krjutškov K, Petropoulos S, Einarsdottir E, Linnarsson S, Lanner F, Månsson R, Hovatta O, Bürglin TR, Katayama S, Kere J.

Sci Rep. 2016 Sep 2;6:32053. doi: 10.1038/srep32053. No abstract available.


The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.

Jouhilahti EM, Madissoon E, Vesterlund L, Töhönen V, Krjutškov K, Plaza Reyes A, Petropoulos S, Månsson R, Linnarsson S, Bürglin T, Lanner F, Hovatta O, Katayama S, Kere J.

Development. 2016 Oct 1;143(19):3459-3469. Epub 2016 Aug 30.


The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility.

Kemiläinen H, Adam M, Mäki-Jouppila J, Damdimopoulou P, Damdimopoulos AE, Kere J, Hovatta O, Laajala TD, Aittokallio T, Adamski J, Ryberg H, Ohlsson C, Strauss L, Poutanen M.

Endocrinology. 2016 Oct;157(10):3719-3730. Epub 2016 Aug 4.


Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos.

Madissoon E, Jouhilahti EM, Vesterlund L, Töhönen V, Krjutškov K, Petropoulous S, Einarsdottir E, Linnarsson S, Lanner F, Månsson R, Hovatta O, Bürglin TR, Katayama S, Kere J.

Sci Rep. 2016 Jul 14;6:28995. doi: 10.1038/srep28995.


Microparticles reveal cell activation during IVF - a possible early marker of a prothrombotic state during the first trimester.

Olausson N, Mobarrez F, Wallen H, Westerlund E, Hovatta O, Henriksson P.

Thromb Haemost. 2016 Aug 30;116(3):517-23. doi: 10.1160/TH15-12-0970. Epub 2016 Jul 14.


Derivation of Human Skin Fibroblast Lines for Feeder Cells of Human Embryonic Stem Cells.

Unger C, Felldin U, Rodin S, Nordenskjöld A, Dilber S, Hovatta O.

Curr Protoc Stem Cell Biol. 2016 Feb 3;36:1C.7.1-11. doi: 10.1002/9780470151808.sc01c07s36. Review.


Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model.

Plaza Reyes A, Petrus-Reurer S, Antonsson L, Stenfelt S, Bartuma H, Panula S, Mader T, Douagi I, André H, Hovatta O, Lanner F, Kvanta A.

Stem Cell Reports. 2016 Jan 12;6(1):9-17. doi: 10.1016/j.stemcr.2015.11.008. Epub 2015 Dec 24.


Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines.

Puttonen KA, Ruponen M, Naumenko N, Hovatta OH, Tavi P, Koistinaho J.

Front Cell Neurosci. 2015 Dec 8;9:473. doi: 10.3389/fncel.2015.00473. eCollection 2015.


A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells.

Kjartansdóttir KR, Reda A, Panula S, Day K, Hultenby K, Söder O, Hovatta O, Stukenborg JB.

PLoS One. 2015 Dec 2;10(12):e0144029. doi: 10.1371/journal.pone.0144029. eCollection 2015.


Human embryonic stem cells.

Damdimopoulou P, Rodin S, Stenfelt S, Antonsson L, Tryggvason K, Hovatta O.

Best Pract Res Clin Obstet Gynaecol. 2016 Feb;31:2-12. doi: 10.1016/j.bpobgyn.2015.08.010. Epub 2015 Sep 11. Review.


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