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The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes-associated osteoarthritis.

Vaamonde-Garcia C, Courties A, Pigenet A, Laiguillon MC, Sautet A, Houard X, Kerdine-Römer S, Meijide R, Berenbaum F, Sellam J.

J Biol Chem. 2017 Sep 1;292(35):14505-14515. doi: 10.1074/jbc.M117.802157. Epub 2017 Jul 6.


Knee and hip intra-articular adipose tissues (IAATs) compared with autologous subcutaneous adipose tissue: a specific phenotype for a central player in osteoarthritis.

Eymard F, Pigenet A, Citadelle D, Tordjman J, Foucher L, Rose C, Flouzat Lachaniette CH, Rouault C, Clément K, Berenbaum F, Chevalier X, Houard X.

Ann Rheum Dis. 2017 Jun;76(6):1142-1148. doi: 10.1136/annrheumdis-2016-210478. Epub 2017 Mar 15.


Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.

Mével E, Merceron C, Vinatier C, Krisa S, Richard T, Masson M, Lesoeur J, Hivernaud V, Gauthier O, Abadie J, Nourissat G, Houard X, Wittrant Y, Urban N, Beck L, Guicheux J.

Sci Rep. 2016 Sep 19;6:33527. doi: 10.1038/srep33527.


Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients.

Deligne C, Casulli S, Pigenet A, Bougault C, Campillo-Gimenez L, Nourissat G, Berenbaum F, Elbim C, Houard X.

Osteoarthritis Cartilage. 2015 Nov;23(11):1843-52. doi: 10.1016/j.joca.2014.12.007.


Characterization of diabetic osteoarthritic cartilage and role of high glucose environment on chondrocyte activation: toward pathophysiological delineation of diabetes mellitus-related osteoarthritis.

Laiguillon MC, Courties A, Houard X, Auclair M, Sautet A, Capeau J, Fève B, Berenbaum F, Sellam J.

Osteoarthritis Cartilage. 2015 Sep;23(9):1513-22. doi: 10.1016/j.joca.2015.04.026. Epub 2015 May 15.


Protective role of frizzled-related protein B on matrix metalloproteinase induction in mouse chondrocytes.

Bougault C, Priam S, Houard X, Pigenet A, Sudre L, Lories RJ, Jacques C, Berenbaum F.

Arthritis Res Ther. 2014 Jul 1;16(4):R137. doi: 10.1186/ar4599.


Induction of an inflammatory and prodegradative phenotype in autologous fibroblast-like synoviocytes by the infrapatellar fat pad from patients with knee osteoarthritis.

Eymard F, Pigenet A, Citadelle D, Flouzat-Lachaniette CH, Poignard A, Benelli C, Berenbaum F, Chevalier X, Houard X.

Arthritis Rheumatol. 2014 Aug;66(8):2165-74. doi: 10.1002/art.38657.


Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis.

Laiguillon MC, Houard X, Bougault C, Gosset M, Nourissat G, Sautet A, Jacques C, Berenbaum F, Sellam J.

Arthritis Res Ther. 2014 Jan 31;16(1):R38. doi: 10.1186/ar4467.


Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain.

Pecchi E, Priam S, Gosset M, Pigenet A, Sudre L, Laiguillon MC, Berenbaum F, Houard X.

Arthritis Res Ther. 2014 Jan 20;16(1):R16. doi: 10.1186/ar4443.


Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis.

Houard X, Goldring MB, Berenbaum F.

Curr Rheumatol Rep. 2013 Nov;15(11):375. doi: 10.1007/s11926-013-0375-6. Review.


Use of autologous growth factors in aging tendon and chronic tendinopathy.

Nourissat G, Houard X, Sellam J, Duprez D, Berenbaum F.

Front Biosci (Elite Ed). 2013 Jun 1;5:911-21. Review.


Identification of soluble 14-3-3∊ as a novel subchondral bone mediator involved in cartilage degradation in osteoarthritis.

Priam S, Bougault C, Houard X, Gosset M, Salvat C, Berenbaum F, Jacques C.

Arthritis Rheum. 2013 Jul;65(7):1831-42. doi: 10.1002/art.37951.


Why subchondral bone in osteoarthritis? The importance of the cartilage bone interface in osteoarthritis.

Mahjoub M, Berenbaum F, Houard X.

Osteoporos Int. 2012 Dec;23 Suppl 8:S841-6. doi: 10.1007/s00198-012-2161-0. Epub 2012 Nov 22. Review.


Osteoarthritis, inflammation and obesity.

Berenbaum F, Eymard F, Houard X.

Curr Opin Rheumatol. 2013 Jan;25(1):114-8. doi: 10.1097/BOR.0b013e32835a9414. Review.


Stress-induced cartilage degradation does not depend on the NLRP3 inflammasome in human osteoarthritis and mouse models.

Bougault C, Gosset M, Houard X, Salvat C, Godmann L, Pap T, Jacques C, Berenbaum F.

Arthritis Rheum. 2012 Dec;64(12):3972-81. doi: 10.1002/art.34678.


Induction of the chemokine IL-8/Kc by the articular cartilage: possible influence on osteoarthritis.

Chauffier K, Laiguillon MC, Bougault C, Gosset M, Priam S, Salvat C, Mladenovic Z, Nourissat G, Jacques C, Houard X, Berenbaum F, Sellam J.

Joint Bone Spine. 2012 Dec;79(6):604-9. doi: 10.1016/j.jbspin.2011.12.013. Epub 2012 Feb 16.


Mesenchymal stem cell therapy regenerates the native bone-tendon junction after surgical repair in a degenerative rat model.

Nourissat G, Diop A, Maurel N, Salvat C, Dumont S, Pigenet A, Gosset M, Houard X, Berenbaum F.

PLoS One. 2010 Aug 18;5(8):e12248. doi: 10.1371/journal.pone.0012248.


MR imaging of iron phagocytosis in intraluminal thrombi of abdominal aortic aneurysms in humans.

Nchimi A, Defawe O, Brisbois D, Broussaud TK, Defraigne JO, Magotteaux P, Massart B, Serfaty JM, Houard X, Michel JB, Sakalihasan N.

Radiology. 2010 Mar;254(3):973-81. doi: 10.1148/radiol.09090657.


Thrombus versus wall biological activities in experimental aortic aneurysms.

Coutard M, Touat Z, Houard X, Leclercq A, Michel JB.

J Vasc Res. 2010;47(4):355-66. doi: 10.1159/000265569. Epub 2009 Dec 16.


Immaturity of microvessels in haemorrhagic plaques is associated with proteolytic degradation of angiogenic factors.

Le Dall J, Ho-Tin-Noé B, Louedec L, Meilhac O, Roncal C, Carmeliet P, Germain S, Michel JB, Houard X.

Cardiovasc Res. 2010 Jan 1;85(1):184-93. doi: 10.1093/cvr/cvp253.


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