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Retrospective application of transposon-directed insertion-site sequencing to investigate niche-specific virulence of Salmonella Typhimurium in cattle.

Vohra P, Chaudhuri RR, Mayho M, Vrettou C, Chintoan-Uta C, Thomson NR, Hope JC, Hopkins J, Stevens MP.

BMC Genomics. 2019 Jan 8;20(1):20. doi: 10.1186/s12864-018-5319-0.


Cytokine and Chemokine Concentrations as Biomarkers of Feline Mycobacteriosis.

O'Halloran C, McCulloch L, Rentoul L, Alexander J, Hope JC, Gunn-Moore DA.

Sci Rep. 2018 Nov 23;8(1):17314. doi: 10.1038/s41598-018-35571-5.


ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages.

Waddell LA, Lefevre L, Bush SJ, Raper A, Young R, Lisowski ZM, McCulloch MEB, Muriuki C, Sauter KA, Clark EL, Irvine KM, Pridans C, Hope JC, Hume DA.

Front Immunol. 2018 Oct 1;9:2246. doi: 10.3389/fimmu.2018.02246. eCollection 2018.


An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017).

O'Halloran C, Hope JC, Dobromylskyj M, Burr P, McDonald K, Rhodes S, Roberts T, Dampney R, De la Rua-Domenech R, Robinson N, Gunn-Moore DA.

Transbound Emerg Dis. 2018 Dec;65(6):1872-1884. doi: 10.1111/tbed.12969. Epub 2018 Jul 30.


Direct Manipulation of T Lymphocytes by Proteins of Gastrointestinal Bacterial Pathogens.

Cassady-Cain RL, Hope JC, Stevens MP.

Infect Immun. 2018 Apr 23;86(5). pii: e00683-17. doi: 10.1128/IAI.00683-17. Print 2018 May. Review.


Quantifying the Survival of Multiple Salmonella enterica Serovars In Vivo via Massively Parallel Whole-Genome Sequencing To Predict Zoonotic Risk.

Vohra P, Bugarel M, Turner F, Loneragan GH, Hope JC, Hopkins J, Stevens MP.

Appl Environ Microbiol. 2018 Jan 31;84(4). pii: e02262-17. doi: 10.1128/AEM.02262-17. Print 2018 Feb 15.


Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.

Thomson S, Hamilton CA, Hope JC, Katzer F, Mabbott NA, Morrison LJ, Innes EA.

Vet Res. 2017 Aug 11;48(1):42. doi: 10.1186/s13567-017-0447-0. Review.


Subset-Specific Expression of Toll-Like Receptors by Bovine Afferent Lymph Dendritic Cells.

Werling D, Hope JC, Siddiqui N, Widdison S, Russell C, Sopp P, Coffey TJ.

Front Vet Sci. 2017 Apr 3;4:44. doi: 10.3389/fvets.2017.00044. eCollection 2017.


Enhancing the toolbox to study IL-17A in cattle and sheep.

Wattegedera SR, Corripio-Miyar Y, Pang Y, Frew D, McNeilly TN, Palarea-Albaladejo J, McInnes CJ, Hope JC, Glass EJ, Entrican G.

Vet Res. 2017 Apr 8;48(1):20. doi: 10.1186/s13567-017-0426-5.


Frequency and phenotype of natural killer cells and natural killer cell subsets in bovine lymphoid compartments and blood.

Hamilton CA, Mahan S, Bell CR, Villarreal-Ramos B, Charleston B, Entrican G, Hope JC.

Immunology. 2017 May;151(1):89-97. doi: 10.1111/imm.12708. Epub 2017 Feb 7.


Inhibition of Antigen-Specific and Nonspecific Stimulation of Bovine T and B Cells by Lymphostatin from Attaching and Effacing Escherichia coli.

Cassady-Cain RL, Blackburn EA, Bell CR, Elshina E, Hope JC, Stevens MP.

Infect Immun. 2017 Jan 26;85(2). pii: e00845-16. doi: 10.1128/IAI.00845-16. Print 2017 Feb.


Interactions between natural killer cells and dendritic cells favour T helper1-type responses to BCG in calves.

Hamilton CA, Mahan S, Entrican G, Hope JC.

Vet Res. 2016 Aug 17;47(1):85. doi: 10.1186/s13567-016-0367-4.


Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species.

Morrison LJ, Vezza L, Rowan T, Hope JC.

Trends Parasitol. 2016 Aug;32(8):599-607. doi: 10.1016/ Epub 2016 May 8. Review.


Immunity, safety and protection of an Adenovirus 5 prime--Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calves.

Bull TJ, Vrettou C, Linedale R, McGuinnes C, Strain S, McNair J, Gilbert SC, Hope JC.

Vet Res. 2014 Oct 29;45:112. doi: 10.1186/s13567-014-0112-9.


Natural Killer Cells in Afferent Lymph Express an Activated Phenotype and Readily Produce IFN-γ.

Lund H, Boysen P, Hope JC, Sjurseth SK, Storset AK.

Front Immunol. 2013 Nov 22;4:395. doi: 10.3389/fimmu.2013.00395. eCollection 2013.


Duration of immunity against Mycobacterium bovis following neonatal vaccination with bacillus Calmette-Guérin Danish: significant protection against infection at 12, but not 24, months.

Thom ML, McAulay M, Vordermeier HM, Clifford D, Hewinson RG, Villarreal-Ramos B, Hope JC.

Clin Vaccine Immunol. 2012 Aug;19(8):1254-60. doi: 10.1128/CVI.00301-12. Epub 2012 Jun 20.


Modified vaccinia virus Ankara-based vaccine vectors induce apoptosis in dendritic cells draining from the skin via both the extrinsic and intrinsic caspase pathways, preventing efficient antigen presentation.

Guzman E, Cubillos-Zapata C, Cottingham MG, Gilbert SC, Prentice H, Charleston B, Hope JC.

J Virol. 2012 May;86(10):5452-66. doi: 10.1128/JVI.00264-12. Epub 2012 Mar 14.


Breadth of the CD4+ T cell response to Anaplasma marginale VirB9-1, VirB9-2 and VirB10 and MHC class II DR and DQ restriction elements.

Morse K, Norimine J, Hope JC, Brown WC.

Immunogenetics. 2012 Jul;64(7):507-23. doi: 10.1007/s00251-012-0606-4. Epub 2012 Feb 24.


Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.

Hope JC, Guzman E, Cubillos-Zapata C, Stephens SA, Gilbert SC, Prentice H, Sopp P, Howard CJ, Charleston B.

Vaccine. 2012 Mar 16;30(13):2357-67. doi: 10.1016/j.vaccine.2012.01.036. Epub 2012 Jan 24.


CD205 antigen targeting combined with dendritic cell recruitment factors and antigen-linked CD40L activation primes and expands significant antigen-specific antibody and CD4(+) T cell responses following DNA vaccination of outbred animals.

Njongmeta LM, Bray J, Davies CJ, Davis WC, Howard CJ, Hope JC, Palmer GH, Brown WC, Mwangi W.

Vaccine. 2012 Feb 21;30(9):1624-35. doi: 10.1016/j.vaccine.2011.12.110. Epub 2012 Jan 10.


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