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Items: 1 to 20 of 60

1.

The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.

Wang B, Hom G, Zhou S, Guo M, Li B, Yang J, Monnier VM, Fan X.

Aging Cell. 2017 Apr;16(2):244-261. doi: 10.1111/acel.12548. Epub 2016 Nov 13.

2.

Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens.

Fan X, Zhou S, Wang B, Hom G, Guo M, Li B, Yang J, Vaysburg D, Monnier VM.

Mol Cell Proteomics. 2015 Dec;14(12):3211-23. doi: 10.1074/mcp.M115.050948. Epub 2015 Oct 9.

3.

MHC associations with clinical and autoantibody manifestations in European SLE.

Morris DL, Fernando MM, Taylor KE, Chung SA, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G, Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium., Vyse TJ, Criswell LA.

Genes Immun. 2014 Apr;15(4):210-7. doi: 10.1038/gene.2014.6. Epub 2014 Mar 6.

4.

Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.

Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G; International MHC and Autoimmunity Genetics Network., Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium., Criswell LA, Vyse TJ.

Am J Hum Genet. 2012 Nov 2;91(5):778-93. doi: 10.1016/j.ajhg.2012.08.026. Epub 2012 Oct 18. Erratum in: Am J Hum Genet. 2015 Sep 3;97(3):501.

5.

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Rantapää-Dahlqvist S, Baechler EC, Brown EE, Alarcón GS, Edberg JC, Ramsey-Goldman R, McGwin G Jr, Reveille JD, Vilá LM, Kimberly RP, Manzi S, Petri MA, Lee A, Gregersen PK, Seldin MF, Rönnblom L, Criswell LA, Syvänen AC, Behrens TW, Graham RR.

Nat Genet. 2009 Nov;41(11):1228-33. doi: 10.1038/ng.468. Epub 2009 Oct 18.

6.

European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus.

Chung SA, Tian C, Taylor KE, Lee AT, Ortmann WA, Hom G, Graham RR, Nititham J, Kelly JA, Morrisey J, Wu H, Yin H, Alarcón-Riquelme ME, Tsao BP, Harley JB, Gaffney PM, Moser KL, Manzi S, Petri M, Gregersen PK, Langefeld CD, Behrens TW, Seldin MF, Criswell LA.

Arthritis Rheum. 2009 Aug;60(8):2448-56. doi: 10.1002/art.24707.

7.

Review of recent genome-wide association scans in lupus.

Graham RR, Hom G, Ortmann W, Behrens TW.

J Intern Med. 2009 Jun;265(6):680-8. doi: 10.1111/j.1365-2796.2009.02096.x. Review.

8.

Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.

Ito I, Kawasaki A, Ito S, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Hom G, Graham RR, Takasaki Y, Hashimoto H, Ohashi J, Behrens TW, Sumida T, Tsuchiya N.

Arthritis Rheum. 2009 Feb;60(2):553-8. doi: 10.1002/art.24246.

9.

Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

Kawasaki A, Ito I, Hikami K, Ohashi J, Hayashi T, Goto D, Matsumoto I, Ito S, Tsutsumi A, Koga M, Arinami T, Graham RR, Hom G, Takasaki Y, Hashimoto H, Behrens TW, Sumida T, Tsuchiya N.

Arthritis Res Ther. 2008;10(5):R113. doi: 10.1186/ar2516. Epub 2008 Sep 19.

10.

Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, Seldin MF, Gregersen PK, Behrens TW, Criswell LA.

PLoS Genet. 2008 May 30;4(5):e1000084. doi: 10.1371/journal.pgen.1000084.

11.

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, Lee AT, Chung SA, Ferreira RC, Pant PV, Ballinger DG, Kosoy R, Demirci FY, Kamboh MI, Kao AH, Tian C, Gunnarsson I, Bengtsson AA, Rantapää-Dahlqvist S, Petri M, Manzi S, Seldin MF, Rönnblom L, Syvänen AC, Criswell LA, Gregersen PK, Behrens TW.

N Engl J Med. 2008 Feb 28;358(9):900-9. doi: 10.1056/NEJMoa0707865. Epub 2008 Jan 20.

12.
13.

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus.

Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, de Bakker PI, Le JM, Lee HS, Batliwalla F, Li W, Masters SL, Booty MG, Carulli JP, Padyukov L, Alfredsson L, Klareskog L, Chen WV, Amos CI, Criswell LA, Seldin MF, Kastner DL, Gregersen PK.

N Engl J Med. 2007 Sep 6;357(10):977-86.

14.

Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor.

Guo T, Agaram NP, Wong GC, Hom G, D'Adamo D, Maki RG, Schwartz GK, Veach D, Clarkson BD, Singer S, DeMatteo RP, Besmer P, Antonescu CR.

Clin Cancer Res. 2007 Aug 15;13(16):4874-81.

15.

Ocular effects of exposure to industrial chemicals: clinical management and proteomic approaches to damage assessment.

Bhattacharya SK, Hom GG, Fernandez C, Hom LG.

Cutan Ocul Toxicol. 2007;26(3):203-25. Review.

PMID:
17687686
16.

Full-sequence computational design and solution structure of a thermostable protein variant.

Shah PS, Hom GK, Ross SA, Lassila JK, Crowhurst KA, Mayo SL.

J Mol Biol. 2007 Sep 7;372(1):1-6. Epub 2007 Jun 16. Review.

PMID:
17628593
17.

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell LA, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6758-63. Epub 2007 Apr 5.

18.

A search algorithm for fixed-composition protein design.

Hom GK, Mayo SL.

J Comput Chem. 2006 Feb;27(3):375-8.

PMID:
16380943
19.

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation.

Antonescu CR, Besmer P, Guo T, Arkun K, Hom G, Koryotowski B, Leversha MA, Jeffrey PD, Desantis D, Singer S, Brennan MF, Maki RG, DeMatteo RP.

Clin Cancer Res. 2005 Jun 1;11(11):4182-90.

20.

Dioxane contributes to the altered conformation and oligomerization state of a designed engrailed homeodomain variant.

Hom GK, Lassila JK, Thomas LM, Mayo SL.

Protein Sci. 2005 Apr;14(4):1115-9. Epub 2005 Mar 1.

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