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COPD, stage and treatment in a large outpatient clinic.

Holm CP, Holm J, Nørgaard A, Godtfredsen N.

Eur Clin Respir J. 2017 Jan 4;4(1):1267470. doi: 10.1080/20018525.2017.1267470. eCollection 2017.


IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.

Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR.

Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391.


Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue.

Cavalera M, Axling U, Berger K, Holm C.

Nutr Metab (Lond). 2016 Dec 6;13:91. eCollection 2016.


White Adipose Tissue Browning in the R6/2 Mouse Model of Huntington's Disease.

McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M.

PLoS One. 2016 Aug 3;11(8):e0159870. doi: 10.1371/journal.pone.0159870. eCollection 2016.


Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice.

Heyman-Lindén L, Kotowska D, Sand E, Bjursell M, Plaza M, Turner C, Holm C, Fåk F, Berger K.

Food Nutr Res. 2016 Apr 27;60:29993. doi: 10.3402/fnr.v60.29993. eCollection 2016.


Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma.

Nezgovorova V, Liu Q, Hu B, Villalobos JL, Yan X, Niu N, Holm C, Grant NP, Marone S, Ravage-Mass L, Lee CG, Elias JA, Cohn L, Chupp GL.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S96-7. doi: 10.1513/AnnalsATS.201509-611MG.


Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma.

Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, Weiss ST, Raby BA, Cohn L, Chupp GL.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S104-5. doi: 10.1513/AnnalsATS.201510-681MG.


Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, Hornung V, Lebbink RJ, Duch M, Fitzgerald KA, Bahrami S, Mikkelsen JG, Hartmann R, Paludan SR.

Nat Commun. 2016 Feb 19;7:10680. doi: 10.1038/ncomms10680.


Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial.

Katona G, Sultész M, Farkas Z, Gyimesi A, Hirschberg A, Huszka J, Radvánszky F, Simon Á, Fülöp G, Láng J, Ablonczy M, Nirnberger G, Holm C.

Clin Transl Allergy. 2015 Nov 4;5:38. doi: 10.1186/s13601-015-0084-5. eCollection 2015.


Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines.

Boström EA, Kindstedt E, Sulniute R, Palmqvist P, Majster M, Holm CK, Zwicker S, Clark R, Önell S, Johansson I, Lerner UH, Lundberg P.

PLoS One. 2015 Aug 4;10(8):e0134608. doi: 10.1371/journal.pone.0134608. eCollection 2015.


Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus.

Rasmussen TK, Andersen T, Bak RO, Yiu G, Sørensen CM, Stengaard-Pedersen K, Mikkelsen JG, Utz PJ, Holm CK, Deleuran B.

Arthritis Res Ther. 2015 Jun 9;17:154. doi: 10.1186/s13075-015-0660-z.


Efficacy and safety of nicoboxil/nonivamide ointment for the treatment of acute pain in the low back - A randomized, controlled trial.

Gaubitz M, Schiffer T, Holm C, Richter E, Pisternick-Ruf W, Weiser T.

Eur J Pain. 2016 Feb;20(2):263-73. doi: 10.1002/ejp.719. Epub 2015 Apr 30.


Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma.

Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, Weiss ST, Raby BA, Cohn L, Chupp GL.

Am J Respir Crit Care Med. 2015 May 15;191(10):1116-25. doi: 10.1164/rccm.201408-1440OC.


Toll-like receptor 2 and 4 induced interleukin-19 dampens immune reactions and associates inversely with spondyloarthritis disease activity.

Kragstrup TW, Andersen T, Holm C, Schiøttz-Christensen B, Jurik AG, Hvid M, Deleuran B.

Clin Exp Immunol. 2015 May;180(2):233-42. doi: 10.1111/cei.12577.


Validity and Agreement between the 28-Joint Disease Activity Score Based on C-Reactive Protein and Erythrocyte Sedimentation Rate in Patients with Rheumatoid Arthritis.

Nielung L, Christensen R, Danneskiold-Samsøe B, Bliddal H, Holm CC, Ellegaard K, Slott Jensen H, Bartels EM.

Arthritis. 2015;2015:401690. doi: 10.1155/2015/401690. Epub 2015 Jan 14.


Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.

Gomez JL, Crisafi GM, Holm CT, Meyers DA, Hawkins GA, Bleecker ER, Jarjour N; Severe Asthma Research Program (SARP) Investigators., Cohn L, Chupp GL.

J Allergy Clin Immunol. 2015 Jul;136(1):51-58.e10. doi: 10.1016/j.jaci.2014.11.027. Epub 2015 Jan 13.


Mobile- vs. fixed-bearing total knee replacement.

Tjørnild M, Søballe K, Hansen PM, Holm C, Stilling M.

Acta Orthop. 2015 Apr;86(2):208-14. doi: 10.3109/17453674.2014.968476. Epub 2014 Oct 3.


Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL/6J Mice.

Heyman L, Axling U, Blanco N, Sterner O, Holm C, Berger K.

J Nutr Metab. 2014;2014:403041. doi: 10.1155/2014/403041. Epub 2014 Jan 14.


T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication.

Berg RK, Rahbek SH, Kofod-Olsen E, Holm CK, Melchjorsen J, Jensen DG, Hansen AL, Jørgensen LB, Ostergaard L, Tolstrup M, Larsen CS, Paludan SR, Jakobsen MR, Mogensen TH.

PLoS One. 2014 Jan 3;9(1):e84513. doi: 10.1371/journal.pone.0084513. eCollection 2014.

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